A5077813452- Endometrial and Cervical Cancer Treatments
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Lung Cancer Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer survivorship and care
- Cancer Immunotherapy and Biomarkers
- Advances in Oncology and Radiotherapy
- Cancer, Hypoxia, and Metabolism
- Oral health in cancer treatment
- MRI in cancer diagnosis
- Medical Imaging and Analysis
- Salivary Gland Disorders and Functions
- Radiation Therapy and Dosimetry
- Patient-Provider Communication in Healthcare
- Dysphagia Assessment and Management
- Uterine Myomas and Treatments
- Tracheal and airway disorders
- Advanced X-ray and CT Imaging
- Breast Implant and Reconstruction
McMaster University
2024
University of Washington
2019-2024
Legacy Health
2022-2023
University of California, Davis
2015-2021
UC Davis Comprehensive Cancer Center
2015-2021
University of Washington Medical Center
2020-2021
University of California Davis Medical Center
2017-2020
Seattle Cancer Care Alliance
2020
Florida College
2016
University of Florida
2016
Breast imaging technology plays an important role in breast cancer planning and treatment. Recently, three-dimensional (3D) printing has become a trending issue phantom constructions for medical applications, with its advantages of being customizable cost-efficient. However, there is no current practice the field multi-purpose quality control (QC) multi-modalities imaging. The purpose this study was to fabricate tissue-equivalent materials via 3D technique QC imaging.We used polyvinyl...
Abstract Background Impaired function of masticatory muscles will lead to trismus. Routine delineation these during planning may improve dose tracking and facilitate reduction resulting in decreased radiation-related This study aimed compare a deep learning model with commercial atlas-based for fast auto-segmentation the on head neck computed tomography (CT) images. Material methods Paired masseter (M), temporalis (T), medial lateral pterygoid (MP, LP) were manually segmented 56 CT images...
Abstract To improve image quality and CT number accuracy of fast-scan low-dose cone-beam computed tomography (CBCT) through a deep-learning convolutional neural network (CNN) methodology for head-and-neck (HN) radiotherapy. Fifty-five paired CBCT images from HN patients were retrospectively analysed. Among them, 15 underwent adaptive replanning during treatment, thus had same-day CT/CBCT pairs. The remaining 40 (post-operative) planning 1st fraction with minimal anatomic changes. A 2D U-Net...
Cone-beam computed tomography (CBCT) images acquired during radiotherapy may allow early response assessment. Previous studies have reported inconsistent findings on an association of CBCT-measured tumor volume changes with clinical outcomes. The purpose this pilot study was twofold: (1) to characterize in CBCT-based radiomics features treatment; and (2) quantify the potential delta-radiomics overall survival locally advanced lung cancer. We retrospectively identified 23 patients calculated...
The purpose of this study was to highlight the importance timely brachytherapy treatment for patients with gynecologic, breast, and prostate malignancies, provide a framework clinical practice management in response COVID-19 pandemic.We review amassing evidence help guide timing cancers. Where concrete data could not be found, peer-reviewed expert opinion is provided.There may significant negative impact on oncologic outcomes gynecologic malignancies who have delay completion therapy. Delay...
Polyvinyl chloride (PVC) is a commonly used tissue-mimicking material (TMM) for phantom construction using 3D printing technology. PVC-based TMMs consist of mixture PVC powder and dioctyl terephthalate as softener. In order to allow the clinical use across CT magnetic resonance imaging (MRI) platforms, we evaluated mechanical physical characteristics ten samples. The samples were made with different PVC-softener ratios optimize bioequivalence physiologic human tissue. Phantom...
The recent global events related to the coronavirus disease of 2019 pandemic have significantly changed medical landscape and led a shift in oncologic treatment perspectives. There is renewed focus on preserving outcomes while maintaining accessibility decreasing resource utilization. Brachytherapy, which vital part course many cancers (particularly prostate gynecologic cancers), has ability deliver hypofractionated radiation thus shorten time. Studies early 2000s demonstrated decline...
The aim of this study was to determine the interdisciplinary agreement in identifying post-operative tumor bed.Three radiation oncologists (ROs), four surgeons, and three radiologists segmented nodal beds for patients with oral cavity cancer. Specialty cohort composite contours were created by STAPLE algorithm implementation results interspecialty comparison. Dice similarity coefficient Hausdorff distance utilized compare spatial differentials between specialties.There significant...
Purpose: To evaluate the accuracy of deep-learning-based auto-segmentation superior constrictor, middle inferior and larynx in comparison with a traditional multi-atlas-based method. Methods Materials: One hundred five computed tomography image datasets from 83 head neck cancer patients were retrospectively collected analyzed for deep-learning versus segmentation. Eighty-three images (40 diagnostic 43 planning tomography) used training convolutional neural network, atlas-based model...
This work presents a comprehensive methodology for constructing tissue equivalent mouse phantom using image modeling and 3D printing technology. The can be used in multimodality imaging irradiation experiments, quality control, management. Computed tomography (CT) images of were acquired imported into software. A skeleton skin shell models segmented the software manufactured bone model was constructed with VERO-WHITE material additional ingredients, including photosensitive resin,...
Larynx may alternatively serve as a target or organs at risk (OAR) in head and neck cancer (HNC) image‐guided radiotherapy (IGRT). The objective of this study was to estimate IGRT parameters required for larynx positional error independent isocentric alignment suggest population‐based compensatory margins. Ten HNC patients receiving (RT) with daily CT on‐rails imaging were assessed. Seven landmark points placed on each scan. Taking the most superior‐anterior point C5 vertebra reference...
Purpose: To assess image quality and uncertainty in organ-at-risk segmentation on cone beam computed tomography (CBCT) enhanced by deep-learning convolutional neural network (DCNN) for head neck cancer. Methods: An in-house DCNN was trained using forty post-operative cancer patients with their planning CT first-fraction CBCT images. Additional fifteen repeat simulation (rCT) scan taken the same day (oCBCT) were used validation clinical utility assessment. Enhanced (eCBCT) images generated...
Purpose: To develop a method for constructing customizable, multimodal quality control (QC) imaging phantoms based on 3D printing technology. Materials and Methods: Four were designed constructed through technology using three unique materials. Physical parameters of the printed materials evaluated, including density, shore hardness, porosity, deformation temperature, computed tomography (CT) number, absorption coefficient, accuracy. Imaging performance was studied MRI, CT, PET/MR, PET/CT,...
Background Physician explanation of gynecologic brachytherapy can be overwhelming or induce patient anxiety, and may time-constrained given clinical limitations. We report the first randomized trial an educational video intervention in on patient-reported outcomes. Methods Between February 2020 January 2022, 80 cancer patients prescribed were randomly assigned to either standard informed consent (Arm A) a supplemental 16 min ( https://vimeo.com/403385455/d0716e3cc8 ) via internet B). Primary...
Skin cancer is the most commonly diagnosed malignancy in United States, and invasive cutaneous melanoma responsible for vast majority of skin cancer-related deaths. Treatment options patients with regional nodal disease, in-transit metastases, or locally advanced distant metastatic disease are challenging. Historically survival rates this patient population dismal. Improved systemic control possible using targeted agents checkpoint inhibitors have redefined treatment outcomes. Furthermore,...