A5088619239- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Invertebrate Immune Response Mechanisms
- Aquaculture Nutrition and Growth
- Identification and Quantification in Food
- Immune Response and Inflammation
- Neurobiology and Insect Physiology Research
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Microbial infections and disease research
- Antimicrobial Peptides and Activities
- Bacteriophages and microbial interactions
- Fish Biology and Ecology Studies
- Animal Genetics and Reproduction
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- Escherichia coli research studies
- Clostridium difficile and Clostridium perfringens research
- Animal Virus Infections Studies
- Crustacean biology and ecology
- Advanced biosensing and bioanalysis techniques
- Conducting polymers and applications
- Metal-Organic Frameworks: Synthesis and Applications
- Ginger and Zingiberaceae research
- Cancer-related Molecular Pathways
Nanjing Medical University
2025
Jimei University
2015-2024
Guangxi University
2024
Johns Hopkins University
2024
Ministry of Agriculture and Rural Affairs
2016-2023
Ministry of Education of the People's Republic of China
2019
Ministry of Agriculture Livestock and Fisheries
2017
Ministry of Agriculture and Agro Based Industry
2017
Ministry of Agriculture & Farmers Welfare
2017
State Key Laboratory of Food Science and Technology
2009-2011
Vibrio harveyi is commonly found in salt and brackish water recognized as a serious bacterial pathogen aquaculture worldwide. In this study, we cloned the ferric uptake regulator (fur) gene from V. wild-type strain HA_1, which was isolated diseased American eels (Anguilla rostrata) has length of 450 bp, encoding 149 amino acids. Then, mutant strain, HA_1-Δfur, constructed through homologous recombination suicide plasmid (pCVD442). The HA_1-Δfur exhibited weaker biofilm formation swarming...
Genome-wide association studies have identified thousands of genetic variants associated with non-small cell lung cancer (NSCLC), however, it is still challenging to determine the causal and improve disease risk prediction. Here, we applied massively parallel reporter assays perform NSCLC variant-to-function mapping at scale. A total 1249 candidate were evaluated, 30 potential within 12 loci identified. Accordingly, proposed three architectures underlying susceptibility: multiple in a single...
To develop a vaccine, which can simultaneously prevent the diseases caused by various pathogenic bacteria in fish, we try to find conserved outer membrane protein (OMP) antigen from different bacterial pathogens. In this study, an OMP fragment of 747 bp (named as Omp-G), was highly seven Aeromonas sequences NCBI database, amplified PCR one sobria strain (B10) and two hydrophila strains (B27 B33) with designed specific primers. The sequence cloned into pGEX-2T (6 × His-tag) vector, expressed...
Abstract The OMPs A (OmpA)—of Edwardsiella anguillarum and OmpU of V. vulnificus have been proven to be good antigens. In this study, after construction a vector, new recombinant Omp (rOMP) containing both OmpA was expressed purified. Then, the Japanese eels ( Anguilla japonica ) were intraperitoneally (i.p.) injected with phosphate‐buffered saline (PBS group), formalin‐killed‐cell (FKC group) or (rOMP group). stimulation index whole blood cells in from FKC group significantly higher than...