A5078562721- SARS-CoV-2 and COVID-19 Research
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Navier-Stokes equation solutions
- Tuberculosis Research and Epidemiology
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS Research and Interventions
- Advanced Mathematical Physics Problems
- Data-Driven Disease Surveillance
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Stability and Controllability of Differential Equations
- Hepatitis C virus research
- Geometric Analysis and Curvature Flows
- Long-Term Effects of COVID-19
- Mathematical Dynamics and Fractals
- Folate and B Vitamins Research
- Liver Disease and Transplantation
- Respiratory viral infections research
- Liver Diseases and Immunity
- Heparin-Induced Thrombocytopenia and Thrombosis
- Nonlinear Differential Equations Analysis
- Neonatal Health and Biochemistry
Hangzhou Xixi hospital
2019-2024
Central South University
2023-2024
Northwest University
2021
National Center for AIDS/STD Control and Prevention,China CDC
2018-2020
Chinese Center For Disease Control and Prevention
2016-2020
Hangzhou Seventh Peoples Hospital
2020
To investigate the diagnostic value of serological testing and dynamic variance serum antibody in coronavirus disease 2019 (COVID-19).
Abstract Background The ongoing benefits of coronavirus disease 2019 (COVID-19) nonpharmaceutical interventions (NPIs) for respiratory infectious diseases in China are still unclear. We aimed to explore the changes seven before, during, and after COVID-19 from 2010 2021. Methods monthly case numbers were extracted construct autoregressive integrated moving average (ARIMA) models. Eight indicators NPIs chosen Government Response Tracker system. eight used establish Multivariable generalized...
Background China's National Free Antiretroviral Treatment Program (NFATP) has substantially increased the survival rate since 2002. However, emergence of HIV drug resistance (HIVDR) limits durability and effectiveness antiretroviral treatment (ART) in at risk patients. Method A cross-sectional survey was conducted among patients having received a median 13.9 months ART eight provinces China. Demographic clinical information collected, venous blood sampled for CD4 cell counts, measurement...
Abstract To investigate the prevalence and temporal trend of transmitted drug resistance (TDR), a nationwide cross-sectional survey was conducted among 5627 ART naïve newly diagnosed HIV-infected individuals in 2015 China. Totally 4704 partial pol sequences were obtained. Among them, most common HIV-1 circulating recombinant form (CRF) or subtype CRF01_AE (39.0%), followed by CRF07_BC (35.6%), CRF08_BC (8.9%), B (5.5%). TDR mutations found 3.6% cases, with 1.1% harboring to protease...
Abstract Background China has always been one of the countries with most serious Tuberculosis epidemic in world. Our study was to observe Spatial-temporal characteristics and epidemiology from 2004 2017 Joinpoint regression analysis, Seasonal Autoregressive integrated moving average (SARIMA) model, geographic cluster, multivariate time series model. Methods The data TB January December were obtained notifiable infectious disease reporting system supplied by Chinese Center for Disease Control...
Abstract Stavudine (D4T), zidovudine (AZT), and tenofovir (TDF) along with lamivudine (3TC) are the most widely used HIV treatment regimens in China. China's National Free Antiretroviral Treatment Programme (NFATP) has replaced D4T AZT or TDF standard first-line since 2010. Few studies have evaluated adherence, virological outcome, drug resistance patients receiving antiretroviral therapy (ART) from 2011 to 2015 due changes ART regimen. From 2015, 2787 were examined, 364, 1453, 970 having...
Patients with antiretroviral therapy interruption have a high risk of virological failure when re-initiating (ART), especially those HIV drug resistance. Next-generation sequencing may provide close scrutiny on their minority resistance variant. A cross-sectional study was conducted in patients ART five regions China 2016. Through Sanger and next-generation parallel, genotyped plasma samples. Rates were compared by the McNemar tests. In total, 174 included this study, median 12...
We present an AIDS patient coinfected with Cytomegalovirus, Pneumocystis jirovecii pneumonia, nontuberculous mycobacteria, and COVID-19, who finally recovered from the coinfection. The 36-year-old man had two hospitalizations. In first hospitalization, was diagnosed HIV, COVID-19 quickly accurately, corresponding treatment worked well. second hospitalization can be divided into four stages: (1) Persistent fever period; (2) Pulmonary Progression; (3) ICU (4) Pneumothorax period. During...
Abstract Background The aim of this study was to assess trends in drug resistance and associated clinical programmatic factors at a national level during the rapid scale up ART. Methods Logistic regression used identify with HIVDR. Variables multivariable logistic were included Cochran–Armitage test for trend. Results A total 11,976 patients enrolled study. prevalence HIVDR among who received ART 9–24 months 2003–2008, 2009–2012, 2013–2015 significantly decreased (15.5%, 6.3%, 2.3%,...
Background The longer ongoing benefits of coronavirus disease 2019 (COVID-19) non-pharmaceutical interventions (NPIs) for sexually transmitted diseases (STDs) in China are still unclear. We aimed to explore the changes five STDs (AIDS, hepatitis B, C, gonorrhoea, and syphilis) before, during, after COVID-19 pandemic mainland China, from 2010 2021. Methods number monthly reported cases were extracted website construct Joinpoint regression autoregressive integrated moving average (ARIMA)...
Abstract BackgroundChina has always been one of the countries with most serious tuberculosis epidemic in world. Our study was to observe Spatial-temporal characteristics and epidemiology China from 2004 2017 Joinpoint regression analysis, Seasonal Autoregressive integrated moving average (SARIMA) model, geographic cluster, multivariate time series model.MethodsThe data TB January December were obtained notifiable infectious disease reporting system supplied by Chinese Center for Disease...
This study aimed to explore serum HBV pre-genomic RNA (pgRNA) levels and its associated factors among HBV-infected patients in the real world.
This study aimed to address the diagnostic challenges associated with MYH9-related disorders (MYH9-RDs) and highlight importance of recognizing Döhle body-like inclusions as crucial markers for this condition.
Background and aims The aim of this study was to evaluate the diagnostic value FibroTouch serological models on staging hepatic fibrosis in chronic liver diseases. Methods We recruited 850 patients undergoing biopsy received test before or after within one week, blood taken for routine inspection operation week. were calculated by results clinical information. six analyzed receiver operating characteristic curve (ROC). Results Patients with severe had significantly higher AST, ALT, GGT, RDW,...
Objective: To explore drug resistance of different viral loads, and investigate the relationship between CD4(+)T cell counts in patients with HIV antiretroviral therapy (ART) China from 2003 to 2015. Methods: Data were extracted Chinese National HIVDR Surveillance database For this study, data collected as follows: having received ART for ≥12 months; 18 years or older; demographic characteristics, information ART, counts, load (VL) a total 8 362 collected. Multi-variables non-conditional...
Objective: To evaluate the using value of FibroTouch and six serological models in detecting degree liver fibrosis patients with chronic hepatitis B, an attempt to provide reference for accurate diagnosis. Methods: Two hundred fifty-eight cases B admitted Xixi Hospital Hangzhou from September 1, 2015 2017 were selected. All underwent histopathological examination measurement determine stiffness (LSM). Serum biochemical parameters detected scoring values calculated. SAS 9.4 statistical...
In this work, we study the energy balance for weak solutions of a reduced‐gravity two‐and‐a‐half model in oceanic fluid dynamics. Inspired by work Nguyen et al. (2020), based on some delicate commutator estimates, prove conservation 2D bounded domains under certain regularity conditions.
Abstract In this paper, we present a new regularity criteria for suitable weak solutions to the 3D simplified Ericksen-Leslie system. Moreover, under condition \|\mathbf{u}\|_{L^{q,\infty}_tL^p_x(Q_r(z_0))}+ \|\nabla\mathbf{d}\|_{L^{q,\infty}_tL^p_x(Q_r(z_0))}=K<\infty,~ (\frac{3}{p}+\frac{2}{q}=1~\rm{and}~3
In this paper, we investigate the singular points of suitable weak solutions co-rotational Beris-Edwards $ {\bf{Q}} $-tensor system modeling hydrodynamic motion nematic liquid crystals. More precisely, on one hand, give an upper bound for number at any fixed time; other obtain a parabolic fractal dimension possible set, which is bounded by \frac{455}{321}(\approx1.417) $.
Abstract Background Since the Coronavirus Disease 2019 (COVID-19) was first identified in Wuhan, China, caused by Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) pathogen, disease has been found many countries. Considering lack of effective drugs and rapid spread COVID-19, we did a clinical detailed retrospective analysis 70 discharged patients which can help us to better determine features disease. Method We collected demographic, epidemiological, clinical, laboratory, chest computed...