A5019067466- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Colorectal and Anal Carcinomas
- Endometrial and Cervical Cancer Treatments
- Genital Health and Disease
- Gestational Trophoblastic Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Ovarian cancer diagnosis and treatment
- Liver Disease and Transplantation
- Genetic factors in colorectal cancer
- Global Health and Surgery
- Prenatal Screening and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Hepatitis C virus research
- HER2/EGFR in Cancer Research
- Multiple and Secondary Primary Cancers
- Congenital Diaphragmatic Hernia Studies
- Colorectal Cancer Screening and Detection
- Primary Care and Health Outcomes
- Advances in Oncology and Radiotherapy
- Testicular diseases and treatments
- COVID-19 and healthcare impacts
- Ectopic Pregnancy Diagnosis and Management
- Blood Pressure and Hypertension Studies
The University of Texas MD Anderson Cancer Center
2021-2024
Oregon Health & Science University
2018-2021
Yale University
2018
Dartmouth College
2015
The Steering Committee for the Obstetrics & Gynecology special edition titled "Racism in Reproductive Health: Lighting a Path to Health Equity" formed working group create an equity rubric. goal was provide tool help researchers systematically center health as they conceptualize, design, analyze, interpret, and evaluate research obstetrics gynecology. This commentary reviews rationale, iterative process, literature guiding creation of
We describe the outcomes of The Extension for Community Healthcare Outcomes-Elimination Cervical Cancer in Americas (ECHO-ELA) program, which was developed as a tri-lateral cooperation between Pan American Health Organization (PAHO), U.S. National Institute (NCI) and University Texas MD Anderson Center (MD Anderson). program's purpose is to disseminate strategies cervical cancer prevention structured around three pillars World Organization's (WHO) Elimination Strategy associated 90-70-90...
Although cervical cancer is preventable, significant disparities exist in access to screening and prevention services. In medically underserved areas (MUAs) of Texas, these rates are 55% higher compared the remainder US. 2019, we expanded a multicomponent, comprehensive program improve partnership with 13 clinics mobile vans MUAs Texas. Our multicomponent intervention consists community education patient navigation coupled training/mentoring for local medical providers perform diagnostic...
<h3>Introduction</h3> As cervical cancer screening programs are implemented, an increasing number of women require loop electrosurgical excision procedure (LEEP). Our objective was to describe the pathologic results LEEP specimens performed as part MULHER Study, a prospective trial primary HPV testing for in Mozambique. <h3>Methods</h3> 9,014 underwent followed by thermal ablation those with positive results. 169 had lesions ineligible and LEEP. Pathology reports were reviewed specimen...
•Primary mediastinal choriocarcinoma is rare, especially in female patients.•Genomic losses predominated our case, which has not been previously reported.•This tumor lacked human chorionic gonadotropin and required histologic diagnosis.
Objectives As cervical cancer screening programs are implemented and expanded, an increasing number of women require loop electrosurgical excision procedure (LEEP) for treatment pre-invasive disease. Our objective was to describe the pathological results LEEP specimens performed as part MULHER study identify factors associated with positive margins. Methods The enrolled 9014 who underwent HPV testing followed by visual assessment (VAT) using inspection acetic acid (VIA) thermal ablation...
30 Background: Melanoma is the most prevalent cancer during pregnancy, representing 31% of all gestational cancers, with its incidence rates rising globally. Pregnancy-associated melanoma (PAM) presents unique challenges in diagnosis and management due to maternal physiological hormonal changes, as well consideration fetal impact. This study aims understand impact pregnancy on outcomes optimize patient care. Methods: We conducted a retrospective patients diagnosed PAM at The University Texas...
Advanced endometrial cancer is associated with poor outcomes and few treatment options exist. Recently, the US Federal Drug Administration approved pembrolizumab for of cancers that are deficient in mismatch repair have high microsatellite instability (MSI). Lynch syndrome an autosomal dominant disease causes MSI-high cancer. We report a case 46-year-old woman advanced who experienced progressive after chemotherapy carboplatin paclitaxel. She was then treated single-agent had exceptional...
Endometrial and ovarian cancers are leading causes of cancer death among women. However, there is little data on these patients from low- middle-income countries including Botswana, a country in sub-Saharan Africa. This study reports demographics, treatment, outcomes for with endometrial Botswana. prospective cohort included all prospectively enrolled or who presented to Princess Marina Gaborone Private Hospital between May 2015 2021. Demographic, survival were analyzed. 99 38 included....
PURPOSE Mozambique has one of the highest burdens cervical cancer globally. Treatment options are few as most women present with advanced disease, and there limited trained health professionals care resources. The objective this study was to describe outcomes diagnosed invasive part Mozambican undergoing screening human papillomavirus (HPV) testing in conjunction family planning services (MULHER) study. MATERIALS AND METHODS Women age 30-49 years were prospectively enrolled MULHER offered...
Background: High-risk human papillomavirus (HR-HPV) infection is a risk factor for anal cancer, yet no cancer screening guidelines exist women with lower genital tract HPV-related disease. We sought to describe the prevalence of HR-HPV or cytologic abnormalities in such women. Methods: This cross-sectional study was performed between October 2018 and December 2021. Inclusion criteria were ≥21 years age prior diagnosis high-grade dysplasia/cancer cervix, vagina, vulva. Participants underwent...
Background: Targeting DNA repair and immune checkpoint pathways has been the focus of multiple clinical trials. In this study, we explore association between proteins, response markers, outcome in women with EOC. Methods: Immunohistochemical analysis TMA 181 EOC samples was used to determine expression levels for proteins (PARP, PTEN, p53, H2Ax, FANCD2, ATM) immune-markers (CD4, CD8, CD68, PD-L2, PD-L1, FOXP3). Biomarker correlated data. Prognostic discriminatory ability assessed per...
5530 Background: Cervical cancer is the leading cause of and cancer-related deaths among women in Nepal, due part to a lack access screening limited medical providers trained diagnose treat with preinvasive cervical disease. Cancer Care Nepal has partnered The University Texas MD Anderson Center (MD Anderson) American Society Clinical Oncology (ASCO) implement ‘train trainer’ (TOT) program teach visual inspection acetic acid (VIA), colposcopy, biopsy, cryotherapy, thermal ablation, loop...