Hiroko Machida

ORCID: 0000-0003-2252-3577
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About
Contact & Profiles
Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Ovarian cancer diagnosis and treatment
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Cervical Cancer and HPV Research
  • Bone Tissue Engineering Materials
  • Mesenchymal stem cell research
  • Cancer Risks and Factors
  • Glycosylation and Glycoproteins Research
  • Intraperitoneal and Appendiceal Malignancies
  • Sarcoma Diagnosis and Treatment
  • Tissue Engineering and Regenerative Medicine
  • Global Cancer Incidence and Screening
  • Advanced Proteomics Techniques and Applications
  • Osteoarthritis Treatment and Mechanisms
  • Estrogen and related hormone effects
  • Colorectal and Anal Carcinomas
  • Cancer and Skin Lesions
  • 3D Printing in Biomedical Research
  • Venous Thromboembolism Diagnosis and Management
  • Periodontal Regeneration and Treatments
  • Multiple and Secondary Primary Cancers
  • Reproductive Biology and Fertility
  • Lymphoma Diagnosis and Treatment
  • Nonmelanoma Skin Cancer Studies

Tokai University
2017-2024

Toyohashi Municipal Hospital
2021-2024

University of Southern California
2015-2023

Kumamoto University Hospital
2022

Tokai University Hospital
2021

Los Angeles Medical Center
2015-2019

Gynecologic Oncology Group
2017

Saitama Medical University
2016

Saitama International Medical Center
2016

October 6 University
2016

To investigate the effectiveness of autologous culture-expanded bone marrow mesenchymal cell transplantation for repairing articular cartilage defects, we transplanted cells into nine full-thickness defects patello-femoral joints (including two kissing lesions) in knees three patients, a 31 year-old female, 44 male and 45 male. Three weeks before transplantation, blood was aspirated from iliac crest. Adherent were cultured with media containing serum. Single-passaged collected, embedded...

10.1002/term.8 article EN Journal of Tissue Engineering and Regenerative Medicine 2007-01-01

Human bone marrow-derived mesenchymal cells contain stem (MSCs), which are well known for their osteo/chondrogenic potential and can be used reconstruction. This article reports the viability of cryopreserved human a comparison osteogenic between noncryopreserved with MSC-like characteristics, derived from marrow 28 subjects. The was approximately 90% regardless storage term (0.3 to 37 months). It is clear by fluorescence-activated cell sorter analysis that surface antigens both were...

10.1089/ten.2005.11.663 article EN Tissue Engineering 2005-05-01

To characterize contributing factors for ovarian conservation during surgical treatment endometrial cancer and to examine the association of on survival young women with early-stage, low-grade tumors.This was a population-based study using Surveillance, Epidemiology, End Results program identify surgically treated stage I type (grade 1-2 endometrioid histology) cases diagnosed between 1983 2012 (N=86,005). Multivariable models were used independent conservation. Survival outcomes cause death...

10.1097/aog.0000000000001647 article EN Obstetrics and Gynecology 2016-09-07

Objective: Uterine carcinosarcoma (UCS) is a rare type of high-grade endometrial cancer (EC) that has been understudied with population-based statistics due to its rarity.This study examined temporal trends in the proportion UCS among women EC.Methods: This retrospective observational examining The Surveillance, Epidemiology, and End Results program between 1973-2013.Primary EC cases were eligible for analysis, time-specific was during period.Results: seen 11,000 (4.7%) 235,849 primary...

10.3802/jgo.2018.29.e22 article EN cc-by-nc Journal of Gynecologic Oncology 2018-01-01

To examine the incidence and prognostic effects of intraoperative capsule rupture to assess effectiveness postoperative chemotherapy for tumor in apparent stage I epithelial ovarian cancer.This is a society-based retrospective observational study Japan that examined 15,163 women with IA-IC1 cancer who underwent primary surgical treatment between 2002 2015. Associations cause-specific survival, survival among intraoperatively ruptured cases were by histology type (clear cell n=6,107,...

10.1097/aog.0000000000003507 article EN cc-by-nc-nd Obstetrics and Gynecology 2019-10-10

1. We showed that a nutritional factor was able to attenuate the development of hypertension and its related diseases in stroke-prone spontaneously hypertensive rats (SHRSP). In present study, effect Wakame, an edible brown seaweed, on stroke examined SHRSP. 2. studied treatment with 5% (w/w diet) Wakame powder salt-loaded (0.5% NaCl drinking water) Salt-loaded animals treated cellulose or kaolin were used as controls. significantly delayed signs (P < 0.05) improved survival rate SHRSP...

10.1046/j.1440-1681.2003.03786.x article EN Clinical and Experimental Pharmacology and Physiology 2003-01-01

To examine the association between tumor grade and survival for women with squamous cervical cancer.This retrospective observational study utilized Surveillance, Epidemiology, End Result program data 1983 2013 to cancer known differentiation grade. Multivariable analyses were performed assess independent associations survival.A total of 31,536 identified including 15,175 (48.1%) 3 tumors, 14,084 (44.7%) 2 neoplasms 2,277 (7.2%) 1 tumors. Higher was significantly associated older age, higher...

10.3802/jgo.2018.29.e91 article EN cc-by-nc Journal of Gynecologic Oncology 2018-01-01

This retrospective observational study examined trends, characteristics, and survival of women with synchronous endometrial ovarian cancer (SEOC) in the Surveillance, Epidemiology, End Results Program between 1973 2013. Among 235,454 primary cancer, was seen 4,082 (1.7%) proportion being decreased from 2.0% to 1.6% 1983 2013 (P=0.049); concurrent endometrioid tumors two sites has increased 24.2% 49.9% among SEOC (P<0.001). When compared without histology associated improved cause-specific...

10.18632/oncotarget.25550 article EN Oncotarget 2018-06-18

Objective To examine the association between intrauterine manipulator use and pathological factors oncologic outcomes in patients with endometrial cancer who had laparoscopic hysterectomy Japan. Methods This was a nationwide retrospective cohort study of tumor registry Japan Society Obstetrics Gynecology. Study population 3846 for from January 2015 to December 2017. An automated 1-to-1 propensity score matching preoperative intraoperative demographics performed assess postoperative...

10.1136/ijgc-2023-005102 article EN International Journal of Gynecological Cancer 2024-02-05

To determine the significance of depth and extent lymphovascular space invasion (LVSI) on lymph node metastasis recurrence in endometrial cancer.A case-control study was conducted to examine LVSI-positive (n = 70) LVSI-negative 641) stage I-III cancer cases that underwent hysterectomy-based surgical staging. The risk distant estimated based LVSI patterns.In multivariate analysis, deep (>50% invasion), extensive (≥7 foci/slide) patterns had a significantly increased (incidence 57.6% 72.7%,...

10.1002/jso.24049 article EN Journal of Surgical Oncology 2015-09-22

To examine the survival outcomes in women with endometrial cancer who were taking low-dose aspirin (81-100 mg/d).A multicenter retrospective study was conducted examining patients stage I-IV underwent hysterectomy-based surgical staging between January 2000 and December 2013 (N=1,687). Patient demographics, medical comorbidities, medication types, tumor characteristics, treatment patterns correlated to outcomes. A Cox proportional hazard regression model used estimate adjusted ratio for...

10.1097/aog.0000000000001491 article EN Obstetrics and Gynecology 2016-06-24
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