A5101619488- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Uterine Myomas and Treatments
- DNA and Nucleic Acid Chemistry
- Mycobacterium research and diagnosis
- Endometriosis Research and Treatment
- Cellular Automata and Applications
- Photoreceptor and optogenetics research
- Reproductive tract infections research
- Genetics, Bioinformatics, and Biomedical Research
- Geophysics and Gravity Measurements
- Viral Infections and Immunology Research
- Sarcoma Diagnosis and Treatment
- Pain Mechanisms and Treatments
- Urinary and Genital Oncology Studies
- Advanced Data Storage Technologies
- Advanced Proteomics Techniques and Applications
- Innovative Teaching and Learning Methods
- Tuberculosis Research and Epidemiology
- Lung Cancer Research Studies
- Plant-based Medicinal Research
- Hair Growth and Disorders
- Machine Learning in Bioinformatics
Tokai University
2020-2024
Tokyo National Hospital
2024
Japan Agency for Marine-Earth Science and Technology
2022
National Cancer Centre Japan
2021-2022
Municipal Tsuruga Hospital
2019
Kao Corporation (Japan)
2013-2019
University of Fukui
2019
Development Fund
2017
Imperial Household Agency
1982-2015
Experimental Pathology Laboratories
2015
Objective To examine the association between intrauterine manipulator use and pathological factors oncologic outcomes in patients with endometrial cancer who had laparoscopic hysterectomy Japan. Methods This was a nationwide retrospective cohort study of tumor registry Japan Society Obstetrics Gynecology. Study population 3846 for from January 2015 to December 2017. An automated 1-to-1 propensity score matching preoperative intraoperative demographics performed assess postoperative...
We describe 9 tumors that resemble soft tissue myoepitheliomas but possess certain traits do not fit perfectly into this category. These tumors, herein referred to as "myoepithelioma-like of the vulvar region," occurred in subcutis vulva and surrounding regions adult women aged 24 65 years. Histologically, measured 2 7.7 cm were well circumscribed, focally encapsulated, lobulated. Tumor cells had an epithelioid spindled shape, with fine amphophilic cytoplasm, uniform nuclei vesicular...
Rodents have brownish‐yellow incisors whose colour represents their iron content. Iron is deposited into the mature enamel by ameloblasts that outline surface of teeth. Nrf2 a basic region‐leucine zipper type transcription factor regulates expression range cytoprotective genes in response to oxidative and xenobiotic stresses. We found genetically engineered Nrf2‐deficient mice show decolourization incisors. While wild‐type were brownish yellow, greyish white colour. Micro X‐ray imaging...
ABSTRACT Resistance of Mycobacterium tuberculosis to pyrazinamide (PZA) derives mainly from mutations in the pncA gene. We developed a reverse hybridization-based line probe assay with oligonucleotide probes designed detect . The detection PZA resistance was evaluated 258 clinical isolates M. sensitivity and specificity obtained by this new were both 100%, consistent results conventional susceptibility testing. This can be used sputa patients. It appears reliable widely applicable and, given...
Ovarian cancer is a leading cause of deaths among gynecological cancers, and method to detect early-stage epithelial ovarian (EOC) urgently needed. We aimed develop an artificial intelligence (AI)-based comprehensive serum glycopeptide spectra analysis (CSGSA-AI) in combination with convolutional neural network (CNN) aberrant glycans samples patients EOC. converted expression patterns into two-dimensional (2D) barcodes let CNN learn distinguish between EOC non-EOC. was trained using 60%...
Functions of the lower extremities and bowel bladder must be monitored during releasing surgery for tethered spinal cord syndrome, because neural elements are embedded in lipoma or anomalous tissues. Evoked muscle action potentials external anal sphincter muscle, urethral extremity muscles can indicate promptly whether not involved before surgeon releases cuts tissue release. It is also important to monitor vesical pressure different types innervation from sphincters, spite slow reaction...
Summary Background Dry skin in the winter has been reported to involve scaling, defects water holding and barrier functions, decreased ceramide ( CER ) levels stratum corneum SC ). We previously that a E ucalyptus extract promotes synthesis cultured keratinocytes accelerates recovery of hydration barrier‐disrupted model human skin. Aims One objectives was examine profile its contribution relief dry The other objective assess efficacy treat Patients/Methods Twenty subjects with on their legs...
Abstract Aim Endometrial changes in Japanese transgender men (TGM) on testosterone use remain elucidated. This study aims to present TGM with endometrial cancer and insights from a literature review of similar cases. Furthermore, we investigated the correlation between severe obesity who underwent gender‐affirming surgery. Methods Between July 2020 April 2023, two groups were assessed: 2 43 without A for was conducted. Clinical data retrospectively collected, histopathological evaluation...
Out-of-class study time is essential in students’ language learning, but few studies ELT measure out-of-class or investigate how teachers can encourage, rather than demand it. In Japan, lower might be expected, ranging from zero to an hour per week. This therefore sets out establish those factors that increase without extrinsic motivators such as homework and testing. Results self-reports course evaluations suggest (1) clear aims, (2) strong student–teacher relationships, (3) non-threatening...
The Supranational Tuberculosis Reference Laboratory (NTRL), Bangkok, and Chiangrai Prachanukroh Hospital, Chiangrai, ThailandTo evaluate the diagnostic performance of newly developed line-probe assay (LiPA) kits in tuberculosis (TB) endemic settings.LiPA were used to 404 clinical isolates Mycobacterium species 163 sputum samples Thailand.LiPA able identify M. tuberculosis, avium, intracellulare kansasii with 100% sensitivity specificity when compared commercially available AccuProbe assay....
Comprehensive serum glycopeptide spectra analysis (CSGSA) evaluates >10,000 glycopeptides and identifies unique peaks patterns via supervised orthogonal partial least-squares discriminant modeling. CSGSA was more accurate than cancer antigen 125 (CA125) or human epididymis protein 4 (HE4) for detecting early stage epithelial ovarian cancer. Combined CSGSA, CA125, HE4 had improved diagnostic performance. Thus, may be a useful screening tool
Obstructed hemivagina and ipsilateral renal agenesis (OHVIRA) syndrome is a rare Mullerian duct anomaly characterized by an obstructed hemivagina, agenesis, uterine didelphys. There are only few published case reports of OHVIRA syndrome, cases associated with cancer have rarely been reported. In fact, there one report clear cell carcinoma (CCC) the cervix. Here, we CCC cervix that underwent abdominal radical hysterectomy; also provide short literature review this topic. A 52-year-old woman...
Aims —To compare the performance of a new generation dual amplified enzyme immunoassay (EIA) with molecular method for diagnosis Chlamydia trachomatis, using range urogenital samples, and to assess reliability testing self collected vaginal specimens compared clinician specimens. Methods —Two population groups were tested. For first group, void urine samples from 193 male patients urethritis, endocervical swabs 187 high risk commercial sex workers. All tested by conventional assay (IDEIA...
Abstract We present three cases of post‐traumatic stress disorder (PTSD) that occurred in patients with gynecologic cancers. Case 1 and 2 had ovarian cancer case 3 endometrial cancer. The developed anxiety, difficulty sleeping, complaints various discomforts after their diagnosis. On consulting psychiatrists, PTSD was diagnosed based upon the DSM‐IV classification. In 2, symptoms worsened during patients’ primary treatment interfered ability to continue treatment. Psychiatric interventions...
Owing to the potential benefits of minimally invasive hysterectomy for endometrial cancer, practice pattern has recently shifted in Japan. This study examined trends surgery (MIS) patients with cancer Japan.This retrospective observational Japan Society Obstetrics and Gynecology Tumor Registry database between 2015-2019. time-specific proportion change predictors MIS use initial treatment Japan, compared it abdominal surgery. Additionally, association hospital surgical volume was examined.A...
Background In 1974, Kinoshita reported a case of ‘irregular parasystole’ due to type I second-degree entrance block. Since then, many cases such ‘irregular’ parasystole have been by us. To explain the mechanism parasystole, two theories suggested, namely, ‘electrotonic modulation’ Jalife and Moe, ‘type block’ On contrary, in 1960, et al. concealed bigeminy for first time. The electrocardiographic findings suggested that there are dual re-entrant pathways with markedly long effective...
The primary treatment of patients with advanced ovarian cancer is selected from whether debulking surgery or neoadjuvant chemotherapy. We investigated pretreatment serum microRNA profiles are useful for selecting high-grade serous who obtain better outcomes undergoing