Bao Zhang

ORCID: 0000-0003-0320-2305
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Research Areas
  • Molecular Biology Techniques and Applications
  • Plant tissue culture and regeneration
  • Genetic and phenotypic traits in livestock
  • Genetic Associations and Epidemiology
  • Plant-Microbe Interactions and Immunity
  • Gene expression and cancer classification
  • Polysaccharides and Plant Cell Walls
  • Cancer-related molecular mechanisms research
  • Genetic diversity and population structure
  • Blood disorders and treatments
  • Genomic variations and chromosomal abnormalities
  • Virus-based gene therapy research
  • Research in Cotton Cultivation
  • Plant Gene Expression Analysis
  • Forensic and Genetic Research
  • RNA modifications and cancer
  • Food Quality and Safety Studies
  • Alcohol Consumption and Health Effects
  • Animal Genetics and Reproduction
  • Food composition and properties
  • Machine Learning in Bioinformatics
  • Genomics and Rare Diseases
  • Natural product bioactivities and synthesis
  • Enzyme-mediated dye degradation
  • Plant biochemistry and biosynthesis

Hefei University of Technology
2023-2025

Xi'an Jiaotong University
2015-2024

Minzu University of China
2024

Southwest University of Science and Technology
2024

Huazhong Agricultural University
2015-2023

Guiyang Medical University
2019-2023

Henan University of Traditional Chinese Medicine
2022

Xuzhou Central Hospital
2016-2021

Southern Medical University
2002-2020

China Pharmaceutical University
2020

Summary In Brassica napus , yellow petals had a much higher content of carotenoids than white present in small number lines, with violaxanthin identified as the major carotenoid compound rapeseed lines. Using positional cloning we cleavage dioxygenase 4 gene, BnaC3 . CCD responsible for formation flower colour, preferential expression white‐flowered B. Insertion CACTA ‐like transposable element 1 ( TE 1) into coding region disrupted its yellow‐flowered α‐Ionone was volatile apocarotenoid...

10.1111/nph.13335 article EN New Phytologist 2015-02-17

Triple-negative breast cancer (TNBC) accounts for 15% of overall cancer. A lack estrogen receptor (ER), progesterone (PR), and human epidermal growth factor 2 (HER2 receptor) makes TNBC more aggressive metastatic. Wnt signaling is one the important pathways in cellular process; it aberrantly regulated, which leads to progression metastasis. In this study, we designed a therapeutic strategy using combination low dose paclitaxel inhibitor (XAV939), examined effect paclitaxel-combined XAV939...

10.3390/cells8080892 article EN cc-by Cells 2019-08-14

Multisensory information competes for preferential access to consciousness. It remains unknown what neural processes cause one particular modality win multisensory competition and eventually dominate behavior. Thus, in a paradigm which human participants sought make simultaneous auditory visual detection responses, we identify prestimulus poststimulus signals that were associated with dominance on each trial. Behaviorally, responses preceded more frequently than vice versa. Even when by they...

10.1523/jneurosci.3760-14.2015 article EN Journal of Neuroscience 2015-06-17

Cardiovascular disease (CVD) can arise because of chronic inflammation and inflammatory bowel (IBD) is one such where the risk for CVD eventual heart failure increased considerably. The incidence IBD, which refers to both ulcerative colitis Crohn's disease, has been on increase in several countries a potential factor CVD. Although IBD potentially cause venous thromboembolism, its significance arterial stiffening, atherosclerosis, ischemic myocardial infarction only being realized now it...

10.3892/etm.2016.3966 article EN Experimental and Therapeutic Medicine 2016-12-12

This study was to investigate the protective effect of magnetic field (MF) on frozen dough processing quality. The texture, microstructure, rheological and physicochemical properties wheat treated by freezing-thawing cycles under different flux densities (0, 2, 4, 6, 8, 10 mT) were analyzed. Compared with conventional dough, MF-treated had lower hardness higher elasticity. Scanning electron microscope exhibited that MF treatment minimized freezing-induced damages morphology starch gluten,...

10.1016/j.lwt.2023.115227 article EN cc-by-nc-nd LWT 2023-08-01

Introduction: Tobacco, as an economic crop in our country, not only requires changes cultivation practices but also benefits from reasonable fertilization to enhance yield and quality. Microbial organic fertilizers (MOFs) have received considerable attention recent years; however, the relationship between rhizosphere soil microorganisms of tobacco plants physicochemical properties with MOFs remains poorly understood. Methods: This study established experimental control groups, employing a...

10.3389/fenvs.2025.1555622 article EN cc-by Frontiers in Environmental Science 2025-03-26

The domestication of wild goats and subsequent intensive trait-driven crossing, inbreeding, selection have led to dramatic phenotypic purification intermediate breeds for the high-quality production dairy, cashmere wool, meat. Genomic resequencing provides a powerful means direct identification trait-associated sequence variations that underlie molecular mechanisms domestication.Here, we report our effort define such based on data from domestic goat (Capra aegagrus hircus; five each)...

10.1093/gigascience/giy105 article EN cc-by GigaScience 2018-08-27

Schizophrenia (SCZ) is a severe and debilitating mental disorder, the specific genetic factors that underlie risk for SCZ remain elusive. The autism susceptibility candidate 2 (AUTS2) gene has been reported to be associated with autism, suicide, alcohol consumption, heroin dependence. We hypothesized AUTS2 might SCZ. In present study, three polymorphisms (rs6943555, rs7459368, rs9886351) in were genotyped 410 patients 435 controls using polymerase chain reaction-restriction fragment length...

10.3390/ijms151119406 article EN International Journal of Molecular Sciences 2014-10-24

The outbreak of Middle East respiratory syndrome-coronavirus (MERS-CoV) in South Korea April 2015 led to 186 infections and 37 deaths by the end October 2015. MERS-CoV was isolated from imported patient China. envelope (E) protein, a small structural protein MERS-CoV, plays an important role host recognition infection. To identify conserved epitopes E sequence analysis performed comparing proteins 42 strains that triggered severe pandemics infected humans past. predict potential B cell three...

10.1109/tcbb.2017.2702588 article EN IEEE/ACM Transactions on Computational Biology and Bioinformatics 2017-05-29

Abstract Isodon rubescens (Hemsley) H. Hara (Lamiaceae) is a traditional Chinese medicine plant that has been used to treat various human diseases. Oridonin one of the main active ingredients, and route its molecular biosynthesis remains be determined. The study gene expression patterns can provide clues toward understanding biological functions. selection suitable reference genes for normalizing target first steps in any quantitative real-time PCR (RT-qPCR) study. Therefore, validation...

10.1038/s41598-022-22397-5 article EN cc-by Scientific Reports 2022-11-15

The aim of this study was to evaluate the association between hematinic deficiencies and recurrent aphthous stomatitis (RAS).517 RAS patients 187 healthy controls were enrolled in present study. Hematinic deficiencies, including serum ferritin, folic acid, vitamin B12 assessed for each participant. Gender age taken into account collected data statistically analysed.Compared with controls, a significantly higher overall frequency found (p<0.001). When gender account, significant differences...

10.4317/medoral.21885 article EN Medicina oral, patología oral y cirugía bucal 2018-01-01

Interleukin (IL)-8, an important chemokine that regulates the inflammatory response, plays role in periodontitis. Previous studies indicate certain IL-8 gene polymorphisms are associated with periodontitis susceptibility some populations. However, literature is somewhat contradictory, and not all have been examined, particularly Han Chinese individuals. The aim of this study was to investigate association every SNP chronic We analyzed 23 SNPs minor allele frequency (MAF)≥0.01, which were...

10.1371/journal.pone.0104436 article EN cc-by PLoS ONE 2014-08-07

Antithyroid drug (ATD)-induced agranulocytosis is associated with human leukocyte antigen (HLA) and nearby genes in Southeast Asian European populations. The susceptibility of the Han population from northern China to ATD-induced has not been reported. We evaluated associations genetic variants at HLA-B HLA-DRB1 loci 32 candidate single nucleotide polymorphisms (SNPs) 29 patients 140 Graves' disease (GD) as controls. All subjects were descent China. HLA-B*27:05 (P = 1.10 × 10-4), HLA-B*38:02...

10.1038/s41598-017-12350-2 article EN cc-by Scientific Reports 2017-09-14

OBJECTIVE: The transcription factor FOXF2 is reported to be down-regulated in HCC. Its deficiency correlated with shorter disease-free survival and overall of HCC patients; however, the mechanism remains elucidated. MATERIALS AND METHODS: In this study, we performed qRT-PCR stern blotting confirm tissue cell lines. Then line Huh7 transduced shRNA was adopted a series vitro vivo assays evaluate phenotype change, migration, invasion, proliferation, colonization circulating formation metastatic...

10.3233/cbm-170139 article EN Cancer Biomarkers 2017-07-04
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