Dan Yu

ORCID: 0000-0003-0321-4760
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About
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Research Areas
  • Fungal and yeast genetics research
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Resistance
  • Cancer-related gene regulation
  • Plant Disease Resistance and Genetics
  • Natural product bioactivities and synthesis
  • Marine and coastal plant biology
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Legume Nitrogen Fixing Symbiosis
  • Insect Resistance and Genetics
  • Plant Gene Expression Analysis
  • Signaling Pathways in Disease
  • Phytochemistry and Biological Activities
  • Mycorrhizal Fungi and Plant Interactions
  • Religion, Ecology, and Ethics
  • Environmental Philosophy and Ethics
  • Plant Stress Responses and Tolerance
  • Fungal Biology and Applications
  • Plant Physiology and Cultivation Studies
  • Geographies of human-animal interactions
  • Fish Biology and Ecology Studies
  • Rangeland Management and Livestock Ecology
  • Plant Molecular Biology Research

Sichuan Animal Science Academy
2025

Northwest A&F University
2013-2024

Hainan University
2021-2023

Sichuan University
2016-2023

West China Second University Hospital of Sichuan University
2016-2023

The University of Texas MD Anderson Cancer Center
2019-2023

Chinese Academy of Sciences
2011-2023

University of Chinese Academy of Sciences
2023

Yunnan University
2019-2023

University of Cologne
2021-2023

The perception of Phytophthora sojae avirulence (Avr) gene products by corresponding soybean resistance (Rps) causes effector triggered immunity. Past studies have shown that the Avr3a and Avr5 genes P. are genetically linked, encoding a secreted RXLR protein was recently identified. We now provide evidence allelic. Genetic mapping data from F2 progeny indicates co-segregate, haplotype analysis strain collections reveal sequence transcriptional polymorphisms consistent with single genetic...

10.1371/journal.pone.0020172 article EN cc-by PLoS ONE 2011-07-14

Abstract Siberian apricot ( Prunus sibirica L.), an excellent woody oil plant unique to Asia, is well known for its ability produce high‐oil seeds use as a promising feedstock of biodiesel. Based on the investigation natural resources in China early stage, from 74 geographic provenances which can fully reflect overall information were collected. In this research, content, fatty acid composition and biodiesel properties evaluated, key environmental factors that caused variation these...

10.1111/gcbb.12759 article EN cc-by GCB Bioenergy 2020-10-04

Phytophthora sojae is an oomycete and a pathogen of soybean that causes root rot. During infection P. delivers effector proteins into host cells to foster disease. However, effector-triggered immunity (ETI) results when factors are recognized by resistance (R) proteins. We have now identified the Avr1d gene, which encodes predicted protein with amino acid motif Arg-X-Leu-Arg (RXLR). Genetic mapping 16 different isolates segregating F2 population 40 individuals shows RXLR gene Avh6 precisely...

10.1094/mpmi-02-13-0036-r article EN other-oa Molecular Plant-Microbe Interactions 2013-04-03

The aim of this work was to map and identify the Phytophthora sojae Avr1c gene. Progeny from a cross P. strains ACR10×P7076 were tested for virulence on plants carrying Rps1c. Results indicate that avirulence segregates as dominant trait. We mapped locus by performing whole genome re-sequencing composite libraries created pooled samples. Sequence reads avirulent (Pool1) virulent (Pool2) samples aligned reference single nucleotide polymorphisms (SNP) identified each pool. High quality SNPs...

10.1371/journal.pone.0089738 article EN cc-by PLoS ONE 2014-02-24

Juvenile Yoshitomi tilapia is often infected by pathogens and results in low-level survival rate. Bacillus subtilis, as a probiotic, may have beneficial effects on Y. with compound 1-deoxynojirimycin (DNJ), which has antibacterial activities. The of dietary probiotic supplementation tilapias were evaluated. was fed B. subtilis for 56 d. Aeromonas hydrophila rate compared. Dietary increased weight gain rate, specific growth, food conversion ratios intake tilapia. diet improved the cumulative...

10.1016/j.ejbt.2017.08.006 article EN cc-by-nc-nd Electronic Journal of Biotechnology 2017-09-04

Endo-β-1,4-Xylanases are a group of extracellular enzymes that catalyze the hydrolysis xylan, principal constituent plant primary cell wall. The contribution Endo-β-1,4-Xylanase I to both physiology and pathogenesis rice blast fungus M. oryzae is unknown. Here, we characterized biological function two endoxylanase (MoXYL1A MoXYL1B) genes in development using targeted gene deletion, biochemical analysis, fluorescence microscopy. Phenotypic analysis ∆Moxyl1A strains showed MoXYL1A required for...

10.1186/s12284-022-00584-2 article EN cc-by Rice 2022-08-12

Hybridisation was carried out between stenospermocarpic seedless grape cultivars (female parents) and Chinese wild Vitis amurensis or its hybrids with cold-resistance alleles (male parents). The aim of this paper was: (1) to evaluate the effects addition plant growth regulator indole-3-acetic acid (IAA) embryo development medium MM3 + 500 mg L−1 casein hydrolysate 1 mmol serine; (2) obtain a batch hybrid offspring by rescue; (3) screen suitable genotypes for rescue. results indicated that...

10.1080/01140671.2016.1153489 article EN New Zealand Journal of Crop and Horticultural Science 2016-04-02

Rationale As a herbal plant used in traditional Chinese medicine, Lamiophlomis rotata (Benth.) Kudo mainly displays its pharmacological effect by promoting blood circulation and hemostasis, dispelling wind, acting as an analgesic. To identify the components contained L. , global detection structural elucidation of both target non‐target medicinal material was performed. Methods ultrasonically extracted with methanol. Separation analysis were achieved using liquid chromatography/quadrupole...

10.1002/rcm.7695 article EN Rapid Communications in Mass Spectrometry 2016-09-05

This report describes the identification of a novel linear B-cell epitope at N-terminus avian infectious bronchitis virus (IBV) nucleocapsid (N) protein. A monoclonal antibody designated 2D2 was prepared against IBV N protein, and series 23 partially overlapping, tagged fragments gene were expressed. These peptides five heterogeneous strains used to identify recognized by using enzyme-linked immunosorbent assay (ELISA) Western blotting analysis. The motif 11DSPAPIIKLGG21, located identified...

10.1089/vim.2009.0094 article EN Viral Immunology 2010-04-01

The evaluation of susceptibility loci is an important addition to the current predictive and screening models in type 1 diabetes Chinese Han population. Therefore, aim this study provide evidence for association between two polymorphisms (rs3747517, rs1990760) from interferon induced with helicase C domain (IFIH1). Here, 464 Type patients 465 control subjects were genotyped these 2 polymorphisms. results indicated that allelic frequencies rs3747517 revealed a strong risk (P < 0.001); yet, no...

10.3109/08916934.2011.633134 article EN Autoimmunity 2011-11-04

Panax ginseng is one of the oldest and most generally prescribed herbs in Eastern traditional medicine to treat diseases. Several studies had documented that leaves have anti-oxidative, anti-inflammatory, anticancer properties similar those root. The aim this research was forecast molecular mechanism on lung cancer by docking network pharmacology so as decipher leaves' entire mechanism. compounds associated with were searched TCMSP. TCMSP Swiss Target Prediction databases used sort out...

10.1038/s41598-021-97115-8 article EN cc-by Scientific Reports 2021-09-14

Objective: KCNT2 gene mutations had been described to cause developmental and epileptic encephalopathies (DEEs). In this study, we presented the detailed clinical features genetic analysis of two unrelated patients carrying de novo variants in reviewed eight different cases available publications. Methods: Likely pathogenic were identified by whole exome sequencing; data retrospectively collected analyzed. Results: Our diagnosed with Ohtahara syndrome followed infantile spasms (IS) possibly...

10.3389/fgene.2021.649556 article EN cc-by Frontiers in Genetics 2021-06-30

Understanding the selectivity of methyltransferase inhibitors is important to dissecting functions each target. From this perspective, we report a chemoproteomic study profile potent protein N-terminal 1 (NTMT1) bisubstrate inhibitor NAH-C3-GPKK (Ki, app = 7 ± nM) in endogenous proteomes. First, describe rational design, synthesis, and biochemical characterization new chemical probe 6, biotinylated analogue NAH-C3-GPKK. Next, systematically analyze networks that may selectively interact with...

10.1021/acschembio.1c00279 article EN ACS Chemical Biology 2021-07-01

Convergent evolution between distantly related taxa often mirrors adaptation to similar environments. Rust fungi and anther smuts, which belong different classes in Pucciniomycotina, have independently evolved a phytoparasitic lifestyle, representing an example of convergent the fungal kingdom. To investigate their adaptations genetic bases underlying lifestyles, we performed genome-wide convergence analysis amino acid substitutions, evolutionary rates, gene gains losses. substitutions were...

10.3389/fgene.2022.863617 article EN cc-by Frontiers in Genetics 2022-04-08

Abstract RNA N 6 -methyladenosine (m A) modification is present in different molecules, including protein-coding mRNAs and non-coding RNAs such as ribosomal (rRNAs). Previous studies identified m A both the 18S 28S rRNAs, but roles of these methylation events are poorly understood due to lack knowledge responsible methyltransferases. Here, we report that mammalian METTL5, a member highly conserved methyltransferase family, specifically methylates adenosine 1832 (A1832) rRNA vivo vitro . We...

10.1101/2020.04.27.064162 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-04-28
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