- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Nosocomial Infections in ICU
- Muscle and Compartmental Disorders
- Renal function and acid-base balance
- Palliative Care and End-of-Life Issues
- Cardiac, Anesthesia and Surgical Outcomes
- Antibiotic Use and Resistance
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Disaster Response and Management
- Patient Safety and Medication Errors
- Healthcare cost, quality, practices
- Liver Disease and Transplantation
- Potassium and Related Disorders
- Viral Infections and Vectors
- Deception detection and forensic psychology
- Neutropenia and Cancer Infections
- Electrolyte and hormonal disorders
- Cardiac Ischemia and Reperfusion
- Intensive Care Unit Cognitive Disorders
- Hematological disorders and diagnostics
D’Or Institute for Research and Education
2019-2025
Hospital São Paulo
2018-2023
Faculdade de Medicina do ABC
2013-2022
Hospital Sírio-Libanês
2013-2021
Universidade do Estado do Pará
2019
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018
Hispanics in Philanthropy
2016
Universidade de São Paulo
2014
The role of the Model for End-Stage Liver Disease (MELD) score in predicting complications, such as Acute Kidney Injury (AKI), after orthotopic liver transplantation (OLT) has yet to be evaluated and serum creatinine may too heavily weighted existing MELD formula, since it many pitfalls cirrhotic patients.Retrospective data perioperative period from consecutive adult OLTs performed January December 2009 were recorded. Univariate multivariate analysis analyze risk factors AKI mortality...
Sepsis-3 definitions were published recently and validated only in high-income countries. The aim of this study was to assess the new criteria’s accuracy stratifying mortality as compared its predecessor (Sepsis-2) a Brazilian public intensive care unit (ICU) investigate whether addition lactate values would improve stratification. Retrospective cohort conducted between 2010 2015 university’s 19-bed ICU. Data from patients admitted ICU with sepsis retrieved prospectively collected database....
Abstract Purpose Acute Kidney Injury (AKI) in COVID-19 patients is associated with increased morbidity and mortality. In the present study, we aimed to develop a prognostic score predict AKI development these patients. Materials methods This was retrospective observational study of 2334 COVID 19 admitted 23 different hospitals Brazil, between January 10th August 30rd, 2020. The primary outcome defined as any increase serum creatinine (SCr) by 0.3 mg/dL within 48 h or change SCr ≥ 1.5 times...
To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on impact of health care-associated infections due to multidrug-resistant bacteria.
Metabolic acid-base adaptation triggered by acute persistent hypercapnia in mechanically ventilated patients with
To describe (1) the energy transfer from ventilator to lungs, (2) match between venous-venous extracorporeal membrane oxygenation (ECMO) oxygen and patient consumption (VO2), (3) carbon dioxide removal with ECMO, (4) potential effect of systemic venous on pulmonary artery pressure.Mathematical modeling approach hypothetical scenarios using computer simulation.The transition protective ventilation ultraprotective in a severe acute respiratory distress syndrome static compliance 20mL/cm H2O...
Controlling blood pH during acute ventilatory failure and hypercapnia in individuals suffering from severe kidney injury (AKI) undergoing continuous renal replacement therapy (CRRT) is of paramount importance critical care settings. In this situation, the optimal concentration sodium bicarbonate dialysate still an unsolved question since high concentrations may worsen carbon dioxide levels low not be as effective controlling pH.We performed a randomized, non-blinded, experimental study. AKI...
To characterize the transport of severely ill patients with extracorporeal respiratory or cardiovascular support.A series 18 in state São Paulo, Brazil is described. All were consecutively evaluated by a multidisciplinary team at hospital origin. The rescued, and membrane oxygenation support was provided on site. then transported to referral hospitals for support. Data retrieved from prospectively collected database.From 2011 2017, aged 29 (25 - 31) years SAPS 3 84 (68 92) main primary...
The aim of this study was to investigate the clinical and laboratorial factors associated with serum sodium variation during continuous renal replacement therapy assess whether perfect admixture formula could predict 24-hour variation.Thirty-six sessions 33 patients, in which affluent prescription unchanged first 24 hours, were retrieved from a prospective collected database then analyzed. A mixed linear model performed large variations (≥ 8mEq/L), Bland-Altman plot generated agreement...
A case of a 30 year-old man presenting with severe systemic chickenpox refractory hypoxemia, central nervous system vasculitis and anuric renal failure is described. Ambulance transportation support using veno-venous extracorporeal membrane oxygenation were necessary until the patient recovered. Ultimately, potential use in low-middle income countries to manage common diseases discussed.
Extracorporeal Membrane Oxygenation (ECMO) is one of the designations used for extracorporeal circuits capable oxygenation, carbon dioxide removal and, eventually, circulatory support. Acute respiratory distress syndrome with severe hypoxemia or acidemia high levels in a scenario low pulmonary tidal volume its mainly indication. Kidney Injury (AKI) and complications such as overload azotemia are common this situation; some epidemiological studies have shown that around 78% patients demanding...
Adverse events are common and responsible for a significant burden in the healthcare setting. Such issues can vary according to local culture relevant policies. The current literature on subject primarily addresses Anglo-Saxon cultures; this study focused understanding perception of disclosure middle-income country Latin America.In descriptive conducted from June-August, 2021, an online self-administered survey about practice used convenience sample 995 Brazilian professionals.Based two...