A5101611319- Viral Infections and Vectors
- Influenza Virus Research Studies
- Animal Disease Management and Epidemiology
- Rabies epidemiology and control
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Respiratory viral infections research
- COVID-19 epidemiological studies
- Viral Infections and Immunology Research
- Virology and Viral Diseases
- Fire effects on ecosystems
- Vector-Borne Animal Diseases
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Digital Contact Tracing
- Zoonotic diseases and public health
- Mosquito-borne diseases and control
- Climate Change and Health Impacts
- Yersinia bacterium, plague, ectoparasites research
- Bacillus and Francisella bacterial research
- Animal Virus Infections Studies
- Image Processing and 3D Reconstruction
- Seismic Waves and Analysis
- SARS-CoV-2 detection and testing
- Data-Driven Disease Surveillance
- COVID-19 Clinical Research Studies
Qinghai New Energy (China)
2025
Shaoxing People's Hospital
2024
Hunan Provincial Center for Disease Control and Prevention
2013-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
Shaoxing University
2024
Queensland University of Technology
2015
State Key Laboratory of Remote Sensing Science
2015
Hunan Normal University
2015
Beijing Normal University
2015
University of Toronto
2013
The first identified cases of avian influenza A(H7N9) virus infection in humans occurred China during February and March 2013. We analyzed data obtained from field investigations to describe the epidemiologic characteristics H7N9 as December 1, 2013.Field were conducted for each confirmed case infection. A patient was considered have a if presence verified by means real-time reverse-transcriptase-polymerase-chain-reaction assay (RT-PCR), viral isolation, or serologic testing. Information on...
A long-standing question in infectious disease dynamics concerns the role of transmission heterogeneities, which are driven by demography, behavior, and interventions. On basis detailed patient contact-tracing data Hunan, China, we find that 80% secondary infections traced back to 15% severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primary infections, indicates substantial heterogeneities. Transmission risk scales positively with duration exposure closeness social interactions...
Abstract Several mechanisms driving SARS-CoV-2 transmission remain unclear. Based on individual records of 1178 potential infectors and their 15,648 contacts in Hunan, China, we estimated key parameters. The mean generation time was to be 5.7 (median: 5.5, IQR: 4.5, 6.8) days, with infectiousness peaking 1.8 days before symptom onset, 95% events occurring between 8.8 9.5 after onset. Most occurred during the pre-symptomatic phase (59.2%). susceptibility infection increases age, while...
Urbanization and rural-urban migration are two factors driving global patterns of disease mortality. There is significant concern about their potential impact on burden the effectiveness current control approaches. Few attempts have been made to increase our understanding relationship between urbanization dynamics, although it generally believed that urban living has contributed reductions in communicable industrialized countries. To investigate this relationship, we carried out...
During the epidemic period of novel H7N9 viruses, an influenza A (H9N2) virus was isolated from a 7-year-old boy with influenza-like illness in Yongzhou city Hunan province November 2013. To identify possible source infection, environmental specimens collected local live poultry markets epidemiologically linked to human case were tested for type and its subtypes H5, H7, H9 using real-time RT-PCR methods as well isolation, four other H9N2 viruses isolated. The results showed that environment...
Background. The pandemic potential of avian influenza viruses A(H5N1) and A(H7N9) remains an unresolved but critically important question.
Abstract Background Several parameters driving the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain unclear, including age-specific differences in infectivity and susceptibility, contribution inapparent infections to transmission. Robust estimates key time-to-event distributions scarce as well. Methods We collected individual records for 1,178 SARS-CoV-2 infected individuals their 15,648 contacts identified by contact tracing monitoring over period from...
Abstract A long-standing question in infectious disease dynamics is the role of transmission heterogeneities, particularly those driven by demography, behavior and interventions. Here we characterize risk between 1,178 SARS-CoV-2 infected individuals their 15,648 close contacts based on detailed contact tracing data from Hunan, China. We find that 80% secondary transmissions can be traced back to 14% infections, indicating substantial heterogeneities. Regression analysis suggests a marked...
Background The transmission of hemorrhagic fever with renal syndrome (HFRS) is influenced by environmental determinants. This study aimed to explore the association between atmospheric moisture variability and for period 1991–2010 in Changsha, China. Methods Findings Wavelet analyses were performed using monthly reported time series data HFRS cases detect quantify periodicity HFRS. A generalized linear model a Poisson distribution log link used relationship climate cases, highlighting...
Abstract Acute haemorrhagic conjunctivitis (AHC) outbreaks are reported frequently in China. However, the transmissibility of AHC remains unclear. This study aimed to calculate disease with and without interventions. An outbreak dataset from January 2007 December 2016 different schools was built Hunan Province. A Susceptible-Infectious-Recovered (SIR) model adopted effective reproduction number ( R eff ) AHC. divided into two parts unc con where represent uncontrolled controlled ,...
Hemorrhagic fever with renal syndrome (HFRS) is an important public health problem in mainland China. HFRS particularly endemic Changsha, the capital city of Hunan Province, one highest incidences The occurrence influenced by environmental factors. However, few studies have examined relationship between variation (such as land use changes and climate variations), rodents occurrence. purpose this study to predict distribution identify risk factors rodent hosts, combining ecological modeling...
Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease caused by hantaviruses. Landscape can influence the risk of hantavirus infection for humans, mainly through its effect on rodent community composition and distribution. It important to understand how landscapes population dynamics different species subsequent HFRS risk.To determine influenced human infection, we monitored communities in prefecture-level cities Loudi Shaoyang, China, from 2006 2013. Land use data were...
China is approaching measles elimination, but indigenous still circulates. County L in has reported measles-containing vaccine (MCV) coverage rates >95% since 2000. Despite high coverage, a large outbreak occurred among young children County. We measured MCV using 5 different methods during an investigation on this and compared our estimates with rates.Reported are determined by aggregating clinic-based data across the county: doses administered each clinic divided number of registered...
Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease caused mainly by two hantaviruses in China: Hantaan virus and Seoul virus. Environmental factors can significantly affect the risk of contracting hantavirus infections, primarily through their effects on rodent population dynamics human-rodent contact. We aimed to clarify environmental favoring rodent-to-human transmission provide scientific evidence for developing effective HFRS prevention control strategies. The 10-year...
The transmission of hemorrhagic fever with renal syndrome (HFRS) is influenced by population dynamics its main host, rodents. It therefore important to better understand rodents' characteristic in epidemic areas.We examined the potential impact food available and climatic variability on HFRS rodent host developed forecasting models. Monthly density climate data Changsha from January 2004 December 2011 were obtained. normalized difference vegetation index (NDVI) temperature dryness (TVDI) for...
Infection rates of rodents have a significant influence on the transmission hemorrhagic fever with renal syndrome (HFRS). In this study, four cities and two counties high HFRS incidence in eastern Hunan Province China were studied, surveillance data rodents, as well cases related environmental variables from 2007 to 2010, collected. Results indicate that distribution infection are closely associated conditions. Hantavirus infections positively correlated temperature vegetation dryness index...
H9N2 avian influenza viruses (AIVs) are highly prevalent and of low pathogenicity in domestic poultry. These show a high genetic compatibility with other subtypes AIVs have been involved the genesis H5N1, H7N9 H10N8 causing severe infection humans. The first case human Hunan province China confirmed November 2013 identified that from live poultry markets (LPMs) near patient's house could be source infection. However, prevalence, distribution characteristics LPMs all over not clear. We...
In recent years, outbreaks of hand, foot, and mouth disease (HFMD) have increased throughout East Southeast Asia, especially in mainland China. The now presents as an increasingly serious public health threat China.A case-control study was designed to examine risk factors associated with death from severe HFMD. A total 553 HFMD cases were collected the National Surveillance System.Multifactorial logistic regression used analyse independent associations between potential influence We found...