- Chronic Lymphocytic Leukemia Research
- Diverticular Disease and Complications
- Colorectal Cancer Surgical Treatments
- Advanced Breast Cancer Therapies
- Gastrointestinal disorders and treatments
- Advanced Aircraft Design and Technologies
- Lymphoma Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Anorectal Disease Treatments and Outcomes
- Rocket and propulsion systems research
- Protein Degradation and Inhibitors
- Tracheal and airway disorders
- Atrial Fibrillation Management and Outcomes
- Hernia repair and management
- Stoma care and complications
- Esophageal and GI Pathology
- Peripheral Artery Disease Management
- Cardiac Valve Diseases and Treatments
- Surgical Sutures and Adhesives
- Vascular Procedures and Complications
- Prostate Cancer Treatment and Research
- Airway Management and Intubation Techniques
- Appendicitis Diagnosis and Management
- Economic and Financial Impacts of Cancer
- Phosphorus and nutrient management
St James's University Hospital
1979-2024
University of Ulster
2022-2024
Belfast City Hospital
2022-2024
Belfast Health and Social Care Trust
2019-2024
Peter MacCallum Cancer Centre
2023
The University of Melbourne
2023
St Vincent's Hospital
2023
University of Ioannina
2023
Pancreatic Cancer Action Network
2023
University of California, Irvine Medical Center
2022
The clinical and physiological results in 13 patients having a colonic J reservoir-anal anastomosis (CR) 15 consecutive straight colo-anal reconstruction (SC) have been compared. groups were matched for age, sex, level of tumour proximal distal resection margins. incidence postoperative complications was similar each group. mean follow-up CR 7 +/- 4 months 47 23 SC patients. Stool frequency per 24 h less than or equal to 2 all while it greater 40 cent the (P 0.05). Three six had minor...
Summary A prospective randomized trial was carried out on 207 patients undergoing laparotomy using three different vertical abdominal incisions–midline, ‘medial’ paramedian incision and ‘lateral’ incision. The lateral is slightly more time-consuming to perform than the other two incisions but there a statistically greater incidence of incisional hernia in midline medial wounds with It suggested that when being considered should be choice.
Abstract In this retrospective international multicenter study, we describe the clinical characteristics and outcomes of patients with chronic lymphocytic leukemia (CLL) related disorders (small lymphoma high‐count monoclonal B lymphocytosis) infected by SARS‐CoV‐2, including development post‐COVID condition. Data from 1540 CLL SARS‐CoV‐2 January 2020 to May 2022 were included in analysis assigned four phases based on cases disposition variants emergence. Post‐COVID condition was defined...
Abstract This study assesses the perforation rate of single and double gloves thus extent to which gloving protects surgeon from diseases transmissible patient. We have also investigated whether offers patient extra protection by reducing wound sepsis. Two hundred adult hernia repairs were performed, first 100 gloved second gloved. Glove rates not significantly different between outer gloves. Although 46 400 perforated there only 15 inner glove perforations eight these matched perforations....
Patients with chronic lymphocytic leukemia (CLL) have a higher risk of developing other malignancies (OMs) compared to the general population. However, impact CLL-related factors and CLL-directed treatment is still unclear represents focus this work. We conducted retrospective international multicenter study assess incidence OMs detect potential in 19,705 patients CLL, small lymphoma, or high-count CLL-like monoclonal B-cell lymphocytosis, diagnosed between 2000 2016. Data collection took...
Abstract The growing environmental concerns and stringent regulations in the oil gas industry have necessitated development of corrosion inhibitor products with improved profiles. focus this study is on application that comply current CEFAS comparison to those no longer meet criteria. In conventional inhibitors, these inhibitors are evaluated for their effectiveness mitigating harsh environments, particularly under hydrodynamic, high-pressure, high-temperature conditions. Static dynamic...
Pruritus ani is a common and socially embarrassing condition which often poorly managed. It classified as idiopathic where the symptoms are usually transitory or secondary when more persistent itch experienced. The aim of this study was to establish cause pruritus in group patients referred combined colorectal dermatological clinic, determine most appropriate treatment.Forty consecutive with were over 6-month period from either general practitioner another hospital consultant clinic. They...
An enterovesical fistula (EVF) is an uncommon condition requiring careful and sometimes extensive preoperative investigation. Our experience over a 10-year period has been reviewed with emphasis on the diagnostic investigations performed.Forty-two patients (30 male) have studied. Presenting symptoms, investigations, subsequent treatment reviewed.The site of fistulae were; 37 colonic, 2 rectal, 3 ileal. The commonest presenting symptoms pneumaturia 75%, faecaluria 63% urinary tract infections...
The study investigated water treatment sludge (WTS) as a phosphorus (P) adsorbent and examined the release of organic matter during P adsorption process. Previous studies indicated that WTS is an effective for but also releases matter, which may affect organoleptic properties treated water, no has characterised conducted in-depth on its behaviours. This process from four different samples. offers results 60-day column experiment indicate columns effectively removed majority 2 mg/L feed...
Albumin Redhill is an electrophoretically slow genetic variant of human serum albumin that does not bind 63Ni2+ and has a molecular mass 2.5 kDa higher than normal albumin. Its inability to Ni2+ was explained by the finding additional residue Arg at position -1. This did explain basis variation (since proalbumin contains adjacent residues -1 -2) or increase in apparent mass. Fractionation tryptic digests on concanavalin A-Sepharose followed peptide mapping bound unbound fractions sequence...
We present our experience in 850 consecutive patients who had a laparotomy through lateral paramedian incision during the period 1977-1981. These underwent both elective and emergency procedures covering wide range of intra-abdominal conditions, high incidence factors known to predispose wound dehiscence incisional hernia formation. Follow-up each case for at least 1 year revealed no dehiscences 3 hernias (0.37 per cent). conclude that is inherently strong this strength due splintage by...
Neointimal hyperplasia and thrombosis initiated by platelet activity may contribute to the failure of femoropopliteal Dacron bypass grafts. We have therefore undertaken a randomised prospective double blind trial comparing efficacy combination acetyl salicylic acid (ASA) 330 mg dipyrida mole (DPM) 75 three times daily, with placebo in maintaining patency grafts implanted relieve disabling claudica tion. Patients received either ASA/DPM or commencing pre-opera tively continuing for 12 months....
Abstract Objectives/Hypothesis Endoscopically guided percutaneous dilational tracheotomy (PDT) has become a well‐established alternative to the more traditional open tracheotomy, yet its use by otolaryngologists is limited. As airway management specialists, should be familiar with wide range of definitive procedures, including PDT. Few otolaryngology programs teach technique. The objective present study was determine complication rate and outcome PDT after introduction in residency teaching...
Abstract This report describes the characteristics and outcomes of 18 heavily pretreated patients with multiple myeloma (MM) who were subsequently treated selinexor. is a case series MM selinexor dexamethasone (Sd) or selinexor, bortezomib, (SVd) in 12 hospitals UK between 2019 2021. Eight received Sd 10 SVd. Patients median five prior treatment lines, including immunomodulatory agents 94% proteasome inhibitors 94%. Ten (55%) had triple‐class refractory disease. Six evaluable achieved...