A5090706945- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Lipid Membrane Structure and Behavior
- Intracranial Aneurysms: Treatment and Complications
- Cellular transport and secretion
- Hemodynamic Monitoring and Therapy
- Head and Neck Surgical Oncology
- Cerebrovascular and Carotid Artery Diseases
- Cerebral Venous Sinus Thrombosis
- Glioma Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
- Spinal Cord Injury Research
- Neural and Behavioral Psychology Studies
- Neurofibromatosis and Schwannoma Cases
- Brain Metastases and Treatment
- Acute Ischemic Stroke Management
- Cardiovascular Health and Disease Prevention
- Spinal Dysraphism and Malformations
- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Spinal Fractures and Fixation Techniques
- Trigeminal Neuralgia and Treatments
- Healthcare Technology and Patient Monitoring
Boston Medical Center
2012-2024
Boston University
2012-2024
Boston Children's Hospital
2024
SUNY Upstate Medical University
2002-2009
Syracuse University
1990-2000
State University of New York
1995-1997
University of Kansas
1987
University of Kansas Medical Center
1982
We used retrograde transport of WGA-HRP to examine the origin thalamic inputs “hand” representation in primary motor cortex macaques (Macaca nemestrina). Injections were placed either crest precentral gyrus or rostral bank central sulcus. The sites for injection sulcus determined by using intracortical stimulation map location hand representation. found that and receive their predominant input from different subdivisions ventrolateral thalamus. Ventralis posterior lateralis pars oralis...
<h3>Objective:</h3> To investigate the temporal pattern and relevant associations of CSF inflammatory measures after intraventricular hemorrhage (IVH). <h3>Methods:</h3> We analyzed prospectively collected cell counts protein glucose levels from participants in Clot Lysis Evaluation Accelerated Resolution IVH phase III (CLEAR III) trial. Corrected leukocyte count index were calculated to adjust for leukocytes attributable circulating blood. Data chronologically plotted. (daily, mean, median,...
Evidence-based clinical practice guidelines can facilitate proper evaluation and management of concussions in the emergency department (ED), often initial primary point contact for concussion care. There is no universally adopted set management, extant evidence suggests that there may be variability care practices limited application ED. This study surveyed EDs throughout New England to examine current utilization evidence-based concussions. In 2013, a 32-item online survey was e-mailed...
Exencephaly is a rare precursor of anencephaly in which large amount brain tissue present despite the absence calvaria. It was discovered together with hydramnios near-term fetus. Sonographic, angiographic, and pathologic findings are discussed.
Target detection during active visual search was examined. The chance corrected spatial distribution of target found to be symmetrically distributed around the point fixation and, unexpectedly, independent proximity fixations display boundaries. Memory play a very limited role in detection, but significant guidance eye movements. A model covert shifts used estimate number and required explain observed performance. An increase from one five per across increasing array set size as estimated by...
The brain plays central role in regulating physiological systems, including the skeleto-muscular and locomotor system. Studies of cortico-muscular coordination have primarily focused on associations between movement tasks dynamics specific waves. However, brain-muscle functional networks synchronous among waves muscle activity rhythms that underlie control remain unknown. Here we address following fundamental questions: what are structure networks; whether main network mediators control; how...
The treatment of hydrocephalus often involves the placement a shunt catheter into cerebrospinal ventricular space, though such catheters fail by tissue obstruction. While diverse cell types contribute to obstruction, astrocytes are believed late failure that can occur months after insertion. Using in vitro microfluidic cultures astrocytes, we show applied fluid shear stress leads decrease confluency and loss their typical stellate morphology. Furthermore, exposed moderate for an extended...
Models of cell shape in the rabbit S2 proximal renal tubule were derived from transmission electron micrographs and compared with scanning micrographs. Standard morphometric procedures used to measure basolateral membrane surface density (SVt) relative total epithelial volume numerous zones height. In basal 20% region we also measured fraction (F) intercellular spaces calculated new densities reference only volume, SVi = SVt/F, or cellular SVc SVt/(1-F). Combined use these then enabled us...
Background: Intracranial pressure (ICP) normally ranges from 5 to 15 mmHg. Elevation in ICP is an important clinical indicator of neurological injury, and therefore monitored routinely several conditions guide diagnosis treatment decisions. Current measurement modalities for monitoring are highly invasive, largely limiting the critically ill patients. An accurate noninvasive method estimate would dramatically expand pool patients that could benefit this cranial vital sign. Methods: This...
The medical literature is replete with articles about the Accreditation Council for Graduate Medical Education's 2003 resident duty hour restrictions. Most of these papers describe creative and thoughtful responses to new system. However, others express concern that "80-hour work week" could hamper continuity care educational activities. Nevertheless, if fatigue impairs learning quality, then restrictions seem worthwhile. We add our voices critics' additional reasons. Data support occurs...
Abstract Fatt and Katz ( Nature 166:597–598, 1950; J Physiol 117:109–128, 1952) attributed miniature endplate potentials (MEPPs) to the action of a standard quantity transmitter, quantum (Del Castillo Katz, 124:560–573, 1954). Quantal packets transmitter were proposed be preformed In CNRS Paris (Ed): “Microphysiologie comparée des éléments excitables” 67:245–258, 1957) stored in large numbers motor nerve terminal. Statistical analyses intervals between MEPPs quanta composing small indicated...
Metastatic meningioma is extremely rare, occurring in an estimated 0.1% of cases. We report a case pediatric metastatic to cervical soft tissue and lymph nodes. An 8-year-old boy presented with headaches, dizziness, involuntary eye flickering. Magnetic resonance imaging (MRI) revealed 7.5-cm parasagittal, dural-based mass venous sinus encasement. Therapeutic embolization was followed by bilateral craniotomy, achieving subtotal resection. Histopathologic examination atypical regions...
Benign peripheral nerve sheath tumors are generally considered curable lesions, and surgical resection is recommended as the primary line of treatment. When these occur in brachial plexus, they most frequently accessed via supraclavicular approach. Traditional descriptions this approach have included either transection sternocleidomastoid (SCM) muscle fibers or disarticulation clavicular head SCM muscle. This report presents a simple easy-to-adapt modification that offers greater...
Ganglioglioma is a rare central nervous system neoplasm representing 0.4% to 1.7% of all brain tumors and most frequently occurs in the pediatric population with an incidence 7.6%. These are usually slow-growing well-circumscribed solid or cystic lesions. Gangliogliomatosis infrequently frontal lobe, pineal gland, basal ganglia, hypothalamus, optic chiasm, very few reports brainstem ganglioglioma. We report case 35-year-old female who initially presented headache, vertigo, ataxia, saccadic...
Very small ruptured aneurysms (≤3 mm) demonstrate a significant risk for procedural rupture with endovascular therapy. Since 2007, 1.5-mm-diameter coils have been available (Micrus, Microvention, and ev3), allowing neurointerventionalists the opportunity to offer patients very treatment. In this study, we review clinical angiographic outcome of treated 1.5-mm coil.This is retrospective cohort study in which examined consecutive coil embolization at single institution. The longest linear...