Scars vary from mature linear scars to abnormal excessive such as hypertrophic and keloid scars. Keloid are fibro-proliferative disease entities that reflect an process of wound healing. They can cause pain, itching, stiffness, psychological distress, all which affect quality life. Various treatment options have been advocated ways prevent treat These include noninvasive treatments use silicone gel sheeting compression therapy, invasive intralesional corticosteroid injections, surgery,...

Background: Patient verification by unique identification is an important procedure in health care settings. Risks to patient safety occur throughout settings failure correctly identify patients, resulting the incorrect patient, site procedure, medication, and other errors. To avoid medical malpractice, radio-frequency (RFID), fingerprint scanners, iris technologies have been implemented The drawbacks of these include possibility lose RFID bracelet, infection transmission, impracticality...

Microsurgical free tissue transfer is regarded as the best available method of reconstruction for intractable defects. The ideal soft flap thought to be anterolateral thigh flap. On basis 334 procedures involving latissimus dorsi (LD) flap, we discuss advantages LD over current universal option, and aimed establish whether could also gain status in all reconstructive fields.Three hundred thirty-four using were performed 322 patients between September 2002 July 2012. In accordance with defect...

Impaired wound healing is a significant medical problem. Recently, cell-based therapy focused on stem cells has been developed to overcome the challenges of defective healing. In this study, we aimed evaluate effectiveness adipose-derived (ASCs) in promoting healing, using different techniques for administering them. Dorsal full-thickness skin defects (1 × 1 cm) were created three groups mice that received intravenous ASCs by injection, intramuscular and topical application, respectively....

Purpose This study aimed to compare the antibacterial and wound healing efficacies of chitosan hydrogel with povidone-iodine (PI) hydrogel. Methods The in vitro activities PI hydrogels against Staphylococcus aureus Escherichia coli were evaluated. Nine 6- 8-week-old male Sprague-Dawley rats divided into plain, PI, groups. Each rat received two 10-mm full-thickness dorsal wounds using an excisional splinting model. was treated 0.2 mL gel thrice over course 3 postoperative weeks. Weekly...

Background: Extensive defects of the lower extremities are usually reconstructed with microvascular free flaps because inadequate local tissues and wound complexity. Many attempts have been made to reconstruct such using chimeric flap concept, enabling larger surface areas be used while maintaining economical tissue use. The latissimus dorsi is one most useful tools for resurfacing extensive limb defects. Methods: Twelve patients leg underwent reconstruction between January 2008 March 2012....

Rupture of the Achilles tendon is usually managed by surgical intervention. Recurrent ruptures, segmental defects, and overlying soft tissue defects render reconstructive procedures challenging. In this report, we present double or triple folding technique anterolateral thigh (ALT) free flap, report clinical outcomes reconstruction combined including tissue.From 2008 to 2013, 7 patients underwent defects. The sizes ranged from 9 × 5 12 cm(2) . Combined were reconstructed with ALT flap vastus...

In this study, we compared outcomes in patients with acute hand injury, who were managed or without negative pressure wound therapy (NPWT) after reconstructive surgery. All of the sustained and multitissue injuries identified. After surgery, a conventional dressing was applied Group 1 NPWT 2. The changed every 3 days. mean age Hand Injury Severity Scoring System score both groups not significantly different. Disabilities Arm, Shoulder, (DASH) scores evaluated month all sutures removed year...

Reconstruction of the lateral malleolus or calcaneus region is challenging because poor vascularity, minimal presence soft tissue, and difficulties with flap positioning during after operation. In many cases, local flaps are limited in terms size, durability, vascularity. Free tissue transfer can be useful for complicated wounds. We report here on results reconstruction this using free thoracodorsal artery perforator flaps. Between October 2010 2013, 16 cases defects were reconstructed The...

To use both acellular human dermis and skin grafting simultaneously for improved without contracture. The study also aims to address the lack of research on application an in diverse clinical cases.The examined patients who had received (CGDerm, CGBio, Seoul, Korea) split-thickness (STSG) lower limb, full-thickness defects between September 2012 June 2014. researchers performed chart reviews retrospectively based following factors: gender, age, injury mechanism, size, exposed structure,...

In severe, infected scalp defects, locally available tissues are not sufficient for reconstruction and often unhealthy. this situation, healthy free tissue transfer offers abundant vascularity of uncompromised that can control infections a single-stage reconstruction. Between March 2002 May 2010, 18 patients (20 cases) underwent traumatic defect with coincident as follows: 16 cases postcranioplasty previous open skull fractures 4 defects without cranioplasties. Eighteen 20 latissimus dorsi...

Pseudoaneurysm of the superficial temporal artery is an unusual complication. Diagnosis based on clinical findings and radiologic study. The standard treatment surgical ligation resection, other options include intervention, thrombin injection, conservative treatment. In this article, authors report several cases pseudoaneurysm suggest a protocol to manage artery. We conducted retrospective review 11 patients who underwent between April 2002 July 2011. According duration aneurysm, we divided...

The gluteal fold V-Y advancement flap is a good option for the reconstruction of vulvovaginal defect because it thin, sensate, reliable, and has matched local skin quality. However, in situations where wider deeper needed, alone may not be sufficient to create tension-free closure. To overcome these limitations, we designed modified flap, which 1 or 2 additional transposition flaps at base conventional flap.This study includes total number 16 patients who had received with our new technique...

Tensor fascia lata (TFL) musculocutaneous flaps often require a donor site graft when harvesting large flap. However, major drawback is that it also sacrifices the muscle. To overcome this disadvantage, we designed TFL perforator-based island flap was harvested from near defect and involved transposition within 90 degrees without full isolation of pedicles. We performed procedures on 17 23 flaps, compared outcomes these surgeries. The overall complication rate 27.5% (11 regions). There were...

Early reconstruction of severe open fractures, performed within 7 days the injury, has a better outcome than closure after days. However, uncertain demarcation damaged tissue often results in delayed reconstruction. In this article, we report our surgical outcomes using latissimus dorsi free flap with internal fixation. Twenty‐three patients Gustilo type IIIB tibial fractures Between March 2009 and May 2012 were included study. There 16 cases distal 1/3 fracture tibia, 4 midshaft fracture, 1...

Background Chimeric flaps are often used in reconstructive fields for multiple defects, different functional and extensive defects. In this article, we present the results of use thoracodorsal artery perforator (TDAp) chimeric including a latissimus dorsi (LD) or serratus anterior (SA) muscle to prevent pedicle compression lower extremity reconstruction. Methods Nineteen TDAp were compression. Seven female 12 male. Patients’ age ranged from 32 73 years. After harvesting skin flap, LD SA...

Abstract Background Reconstruction of complicated diabetic lower leg and foot defects involving multiple tissue components remains a challenge. The purpose this report is to introduce thoracodorsal artery perforator (TDAP) chimeric flaps for reconstructing soft defects. Patients methods Between April 2010 August 2016, 17 patients with underwent reconstruction TDAP flaps. Nine were women the mean age was 57.7 years (range 35–73 years). One patient had 3 separate defects, 14 2 dead space. size...

Early implant loading is very important for reducing the duration of missing teeth in human patients. The laminin-derived peptide, DLTIDDSYWYRI motif (Ln2-P3), accelerates bone healing. Therefore, to investigate hypothesis that Ln2-P3 increases response sandblasted, large-grit, acid-etched (SLA) titanium implants, effect peptide on osseointegration SLA implants was evaluated vitro and vivo. Human osteoblast-like cells were cultured untreated, scrambled (SP)-treated, Ln2-P3-treated discs,...

Fibrin sealants have had applications in hemostasis, cohesion, and promotion of healing plastic surgery. In this article, we review cases where fibrin sealant was used to stabilize microvascular pedicles compared with previous free flaps performed without sealant.Between 2008 2010, 62 consecutive patients underwent tissue transfer for reconstruction; involved 33 latissimus dorsi perforator flaps, 14 thoracodorsal artery 9 myocutaneous 3 lateral thoracic transverse rectus abdominis head neck...