A5063781071- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Neuroblastoma Research and Treatments
- Pancreatitis Pathology and Treatment
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Gallbladder and Bile Duct Disorders
- Molecular Biology Techniques and Applications
- Helicobacter pylori-related gastroenterology studies
- Drug-Induced Hepatotoxicity and Protection
- Liver physiology and pathology
- Cancer Cells and Metastasis
- Gastrointestinal disorders and treatments
- Liver Diseases and Immunity
- Microscopic Colitis
- Renal Diseases and Glomerulopathies
- Lung Cancer Research Studies
- Medical Imaging and Pathology Studies
Methodist Hospital
2024-2025
Cornell University
2024
Houston Methodist
2014-2024
Methodist Hospital
2014-2024
Baylor College of Medicine
2016-2023
The University of Texas MD Anderson Cancer Center
2011-2022
Propath Services (United States)
2022
St. Luke's Medical Center
2021
St. Luke's Hospital
2017-2020
Icahn School of Medicine at Mount Sinai
2014-2020
Although hypomagnesemia is common and causes weakness in humans, it not known what effect its correction has on respiratory muscle power. We designed an experiment to test the hypothesis that of will improve measured power lung volumes 16 control subjects 17 patients (11 alcoholics, 6 nonalcoholics) 3 consecutive days. After baseline measurements Day 1, were randomized study was double blinded. Patients given magnesium intravenously or dextrose as placebo. Measurements repeated 2, then if...
Intraoperative delineation of tumor margins is critical for effective pancreatic cancer surgery. Yet, intraoperative frozen section analysis a time-consuming and often challenging procedure that can yield confounding results due to histologic heterogeneity tissue-processing artifacts. We have previously described the development MasSpec Pen technology as handheld mass spectrometry-based device nondestructive tissue analysis. Here, we evaluated usefulness diagnosis ductal adenocarcinoma based...
In India, approximately 40,000 new cases of cancer in children are diagnosed each year. However, there no good studies analyzing their nutritional status. Also, since accurate and sensitive assessment is critical for optimal clinical outcomes through timely remediation malnutrition, it important to assess the relative sensitivity feasibility commonly used screening tools.This observational study analyzed height/length (cm), weight (kg), mid-upper arm circumference (MUAC), triceps skinfold...
This study aims to evaluate the prognostic value of MUC expression in US GC patients. A total 70 tumor specimens were collected from patients who underwent surgery or endoscopic resection between 2013 and 2019 at a tertiary referral center US. status including MUC1, MUC2, MUC5AC, MUC6 was evaluated by immunohistochemical staining. The positive rates 71.4%, 78.6%, 74.3%, 33.3%, respectively. Patients with MUC1 had significantly higher rate aggressive pathologic features diffuse-type cancer...
Background. Hepatocellular carcinoma (HCC) has a rising incidence and mortality in North America. Liver transplantation (LT) with adjunctive therapies offers excellent outcomes. However, HCC recurrences are associated high mortality. We investigate whether adjuvant systemic therapy can reduce recurrence, as shown other malignancies. Methods. Medical records of patients undergoing LT for at single center between January 2016 December 2022 were retrospectively reviewed. Patients stratified...
Background. Perihilar cholangiocarcinoma (phCCA) has excellent outcomes following liver transplantation (LT). Neoadjuvant radiation-based locoregional therapy is standard-of-care. Gemcitabine and cisplatin (gem/cis) combination systemic therapies have improved in advanced settings, but their efficacy pre-LT not been studied. Methods. We review our experience neoadjuvant gem/cis alone versus approaches. Patients with phCCA undergoing LT at a single center between January 2008 February 2023...
Clinically available intraoperative imaging tools to assist surgeons in identifying occult lesions are limited and partially responsible for the high rate of disease recurrence patients with neuroendocrine tumors (NET). Using established clinical efficacy radiolabeled somatostatin analogs as a model, we demonstrate ability fluorescent analog selectively target that overexpress receptor subtype-2 (SSTR2) utility fluorescence-guided surgery (FGS).A multimodality chelator (MMC) was used...
We described a 32-year-old man who developed severe drug-induced liver injury after using Ligandrol (LGD-4033). The diagnosis was confirmed by biopsy that showed cholestatic hepatitis with mild portal, periportal, and perisinusoidal fibrosis. is selective androgen receptor modulator available over the counter via internet.
We report a 52-year-old man who developed drug-induced liver injury after taking Alpha Bolic (contains RAD-140) and Elite both RAD-140 LGD-4033) supplements. Liver biopsy demonstrated diffuse centrilobular canalicular cholestasis, prominent ductular reaction, mild lobular inflammation with rare non-necrotizing epithelioid granuloma suggestive of injury. enzymes returned to normal levels approximately 3 months the patient stopped present mechanism associated 2 selective androgen receptor...
Intraoperative tissue analysis and identification are critical to guide surgical procedures improve patient outcomes. Here, we describe the clinical translation evaluation of MasSpec Pen technology for molecular in vivo freshly excised tissues operating room (OR).An Orbitrap mass spectrometer equipped with a interface was installed an OR. A "dual-path" designed programmed studies 2 parallel systems that facilitated operation Pen. The devices were autoclaved before each procedure used by...