A5071741760- Occupational and environmental lung diseases
- Microwave-Assisted Synthesis and Applications
- Chromium effects and bioremediation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Silicone and Siloxane Chemistry
- Synthesis and properties of polymers
- Occupational exposure and asthma
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Material Properties and Applications
- Neuroendocrine Tumor Research Advances
- Pleural and Pulmonary Diseases
- Heavy Metal Exposure and Toxicity
- Mercury impact and mitigation studies
- Cancer Research and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Advanced Glycation End Products research
- Peroxisome Proliferator-Activated Receptors
- Metabolism and Genetic Disorders
- Plant-based Medicinal Research
- Dendrimers and Hyperbranched Polymers
- Cancer Cells and Metastasis
- Pesticide Residue Analysis and Safety
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Berberine and alkaloids research
- Parasites and Host Interactions
Hangzhou Medical College
2020-2023
Zhejiang Academy of Medical Sciences
2010-2023
South China University of Technology
2008
High-mobility group box 1 (HMGB1) functions as a proinflammatory cytokine and is one of the most intriguing molecules in inflammatory disorders cancers. Notably, HMGB1 potential therapeutic target novel biomarker related diseases. However, diagnostic value for benign malignant asbestos-related diseases (ARDs) remains unclear. In this work, we detected preoperative serum levels Chinese asbestos-exposed (AE) ARDs populations further evaluated patients with certain types ARDs, including those...
Hexavalent chromium [Cr (VI)] is prevalent in ground water some areas, but evidence on the toxic effects of Cr (VI) via ingestion through drinking remains insufficient. The aims our study were to investigate oral oxidative stress and DNA methylation. Thirty-two Sprague-Dawley rats randomly divided into four groups, exposed porassium dichromate (K2Cr2O7; 0, 30, 100, 300 mg/L) for 4 weeks. Mean body weight gain, mean consumption, clinical chemistry determinations, levels plasma measured....
While chrysotile has been commonly used by Chinese textile industry for many years, investigations on the association of exposure with risk mesothelioma in China are scarce. We conducted a case–control study county located at Southeastern China, including 46 cases and 230 individually matched controls. A semi‐quantitative method based experts' assessment was evaluating hand‐spinning exposure. Conditional logistic regression models were to assess asbestos mesothelioma. found that associated...
Biological oxidative responses are involved in the toxicity of multiwall carbon nanotubes (MWCNTs), which may cause asbestos-like pathogenicity. Superoxide dismutase 2 (SOD-2) has been proposed as a biomarker early to mesothelioma-inducing fibers. This study was conducted investigate alteration SOD-2 expression human mesothelial cell lines Met-5A after exposure nontoxic doses MWCNTs and potential signaling pathway. The parameters measured included viability, morphological change, superoxide...
Cr(VI) exposure could produce kinds of intermediates and reactive oxygen species, both which were related to DNA damage. Hyaluronan (HA) has impressive biological functions was reported protect corneal epithelial cells against oxidative damage induced by ultraviolet B, benzalkonium chloride, sodium lauryl sulfate. So the aim our study investigate HA protection on human (HCE) Cr(VI)-induced toxic effects. The HCE cell lines exposed different concentrations K 2 Cr O 7 (1.875, 3.75, 7.5, 15.0,...
IgG4-TIN is the most common pattern of renal involvement in IgG4-related disease. There are several proposed diagnostic criteria recently. Two them by Mayo Clinic and JSN predominant. However, histopathological number IgG4+ plasma cells histological features still under discussion due to low amount tissue biopsy specimens frequency this kind specimens. We aimed screen on archived samples evaluated application two criteria. selected 480 interstitial inflammation for light electron microscopy...
Background Artesunate (ART) has been reported to have an antifibrotic effect in various organs. The underlying mechanism not systematically elucidated. We aimed clarify the of ART on liver fibrosis induced by Schistosoma japonicum ( S . ) experimentally infected rodent model and potential mechanisms. Methods hepatic stellate cells (HSCs) was assessed using CCK-8 Annexin V-FITC/PI staining assays. experimental established Mongolian gerbil with cercariae then treated 20 mg/kg or 40 ART....
Abstract Emulsion polymerization of octamethyl cyclotetrasiloxane (D 4 ) under microwave irradiation (MI) was studied. The polysiloxane (PSi) nanoparticles via cationic ring-opening D were obtained by using the dodecylbenzene sulphonic acid (DBSA), sodium sulphate (SDBS) and poly(ethylene glycol) monooctylphenyl ether (OP-10) as catalyst emulsifiers respectively. particle size analyzer transmission electron microscope (TEM) used to determine PSi emulsions. results show that, emulsions...
Abstract Fibulin-3 is an extracellular matrix glycoprotein widely expressed in various tissues. Tissue fibulin-3 expression have never been reported association with prognosis of mesothelioma. Hence, we sought to determine the between and mesothelioma survival. We made a tissue microarray, which was comprised cancer normal from patients ( n = 82) during period 1998–2017 China. HGMB1 were analyzed by immunohistochemistry method. Kaplan–Meier method Cox proportional hazard models used for...
α, ω-dihydroxyl polydimethylsiloxane (DHPDMS) was prepared via anionic ring-opening polymerization of octamethyl cyclotetrasiloxane (D4) under microwave irradiation (MI) in the presence water. The conversion and rate were calculated by gravimetric method. effect power on investigated. FTIR used to verify DHPDMS at different times. results show that is highest when initial preset 700 W. Compared with conventional heating (CH), equilibrium are both enhanced introduction irradiation. species...
Objective To compare the results of pathological diagnosis 41 patients with malignant mesothelioma between Chinese and Japanese experts, to provide a basis for standard mesothelioma. Methods The medical information tissue samples were collected in hospital Zhejiang Province from 2003 2010. The expression levels calretinin, Wilms' tumor suppressor gene (WT1), podoplanin (D2-40), cytokeratins (CK5/6, AE1/AE3, CAM5.2), epithelial membrane antigen, carcinoembryonic BerEP4, MOC31, thyroid...