A5074086132- SARS-CoV-2 and COVID-19 Research
- Animal Disease Management and Epidemiology
- Assisted Reproductive Technology and Twin Pregnancy
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- HIV Research and Treatment
- COVID-19 Clinical Research Studies
- T-cell and B-cell Immunology
- Immunodeficiency and Autoimmune Disorders
- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 detection and testing
- HIV/AIDS Research and Interventions
- Influenza Virus Research Studies
- Respiratory viral infections research
- vaccines and immunoinformatics approaches
- COVID-19 epidemiological studies
- Immune Cell Function and Interaction
- Health Education and Validation
- Vaccine Coverage and Hesitancy
- HIV-related health complications and treatments
Emory University
2023-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2021-2023
Instituto do Coração
2021-2022
Universidade de São Paulo
2022
Even after over 2 years of the COVID-19 pandemic, research on rapid, inexpensive, and accurate tests remains essential for controlling avoiding global spread SARS-CoV-2 across planet during a potential reappearance in future waves or regional outbreaks. Assessment serological responses can be beneficial population-level surveillance purposes, supporting development novel vaccines evaluating efficacy different immunization programs. This especially relevant broadly used inactivated whole...
Human immunodeficiency virus (HIV) persistence during antiretroviral therapy (ART) is associated with heightened plasma interleukin-10 (IL-10) levels and PD-1 expression. We hypothesized that IL-10 blockade would lead to control of viral rebound following analytical treatment interruption (ATI). Twenty-eight ART-treated, simian (SIV)mac
CoronaVac is an inactivated SARS-CoV-2 vaccine that has been rolled out in several low and middle-income countries including Brazil, where it was the mainstay of first wave immunization healthcare workers elderly population. We aimed to assess T cell antibody responses vaccinated individuals as compared convalescent patients. detected IgG against antigens, neutralizing antibodies reference Wuhan strain used peptides detect IFN-g IL-2 specific a group (N = 101) 72) individuals. The frequency...
Introduction Considering the likely need for development of novel effective vaccines adapted to emerging relevant CoV-2 variants, increasing knowledge epitope recognition profile among convalescents and afterwards vaccinated with identification immunodominant regions may provide important information. Methods We used an RBD peptide microarray identify IgG IgA binding in serum 71 COVID-19 18 individuals. Results found a set antibody epitopes, each recognized by more than 30% tested cohort,...
<title>Abstract</title> HIV persistence during antiretroviral therapy (ART) is associated with heightened plasma IL-10 levels and the expression of co-inhibitory receptor PD-1. We hypothesized that PD-1 blockade would synergize to boost immune function leading control viral rebound post-analytical treatment interruption (ATI). Twenty-eight ART-treated, SIVmac239-infected rhesus macaques (RMs) were treated anti-IL-10 alone, in combination anti-PD-1 (« combo »), or vehicle. ART was interrupted...
Background The influence of the host genome on coronavirus disease 2019 (COVID-19) susceptibility and severity is supported by reports monozygotic (MZ) twins where both were infected simultaneously with similar outcomes, including several who died due to SARS-CoV-2 infection within days apart. However, successive exposures pathogens throughout life along other environmental factors make immune response unique for each individual, even among MZ twins. Case presentation methods Here we report...
Abstract Background CoronaVac is an inactivated SARS-CoV-2 vaccine that has been rolled out in several low and middle-income countries including Brazil, where it was the mainstay of first wave immunization health care workers elderly population. We aimed to assess T cell antibody responses vaccinees as compared convalescent subjects. Methods detected IgG against antigens, neutralizing antibodies original strain, used peptides detect IFN-g IL-2 specific a cohort (N=101) (N=72) individuals....