A5101878808- Ocular Oncology and Treatments
- Histiocytic Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Bone Tumor Diagnosis and Treatments
- IgG4-Related and Inflammatory Diseases
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Sarcoma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Vascular Tumors and Angiosarcomas
- CNS Lymphoma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Ophthalmology and Eye Disorders
- Nanoplatforms for cancer theranostics
- Proteoglycans and glycosaminoglycans research
- Parvovirus B19 Infection Studies
- Ocular Disorders and Treatments
- Lymphoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Retinopathy of Prematurity Studies
- Antimicrobial Resistance in Staphylococcus
- Parasitic infections in humans and animals
- Nonmelanoma Skin Cancer Studies
- Cancer Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
Chinese PLA General Hospital
2019-2024
People's Liberation Army No. 150 Hospital
2021
Chinese People's Liberation Army
2021
Chinese People's Armed Police Force
2014-2017
Chinese People's Armed Police General Hospital
2006-2017
Valosin containing protein (VCP)/p97 plays various important roles in cells. Moreover, elevated expression of VCP hepatocellular carcinoma (HCC) is correlated with increased incidence recurrence. But the role HCC progression vitro and vivo unclear. And there are few reports about regulation mechanism on HCC. In this study, it was identified that level frequently human tissues. addition, down-regulation siRNAs could dramatically suppress genesis tumor vivo. It found miR-129-5p directly...
To investigate the magnetic resonance imaging (MRI) features of orbital Langerhans cell histiocytosis (LCH) to improve diagnostic accuracy.We retrospectively reviewed clinical manifestations and MRI findings 23 patients with histopathology-confirmed LCH orbit. The were evaluated for following: (a) symptoms, (b) disease duration, (c) location, (d) configuration, (e) margin, (f) MR signal intensity enhanced performance.Eighteen (78%) in our series male, only five (22%) female, mean age at...
Alveolar soft part sarcoma (ASPS) is a rare tissue neoplasm. The incidence of orbital involvement the highest in ASPS arising head and neck region. However, limited information available regarding its clinical characteristics. present study presents manifestations, imaging findings, pathological features, treatment strategies prognosis records 8 cases over last 15 years single hospital, along with review literature. Included were 3 male 5 female patients, median age at presentation being 9.5...
Spheno-orbital meningioma (SOM) represents a unique variant of sphenoid wing meningiomas, distinguished by its propensity for bone infiltration and cranio-orbital involvement. SOM exhibits considerable incidence misdiagnosis recurrence. To elucidate the clinical, radiological, pathological characteristics SOM. Review electronic medical records, histopathology, radiological images follow-up information 100 patients. Of patients (28 males, 72 females) with SOM, mean age was 46.8 ± 12.6 years...
To investigate whether the expression level of valosin-containing protein (VCP) is correlated with prognosis primary orbital mucosa-associated lymphoid tissue (MALT) lymphoma.VCP in 58 samples from MALT lymphoma patients was determined by immunohistochemisty using monoclonal antibodies. Correlations between VCP and were clarified statistical analysis.It found that percentage positive cells ranged 32% to 95%. The divided into two groups (level 1 2) according median value (45%) cells. It...
To analyze the clinical features, histopathologic classification and frequencies of various types recurrent orbital space-occupying lesions.A retrospective study was carried out in 253 consecutive patients with lesions treated by surgical excision Institute Orbital Diseases, General Hospital Armed Police Force from January 2009 to December 2010.The included 123 males 130 females aged 2 78 years (mean, 36.2 years), last recurrence interval after operation ranged 1 month 40 (median, 4.75...
Staphylococcus aureus causes a wide range of infectious diseases. Treatment these infections has become increasingly difficult due to the widespread emergence antibiotic-resistant strains; therefore, it is essential explore effective alternatives antibiotics. A secreted protein S. aureus, known as eLtaS, an extracellular released from bacterial membrane protein, LtaS. However, role eLtaS in pathogenesis remains largely unknown. Here we show dramatically aggravates infection by binding C3b...
Abstract Background To assess the activities of heparanase‐1 and elements hedgehog signalling pathway in alveolar orbital rhabdomyosarcoma. Methods Specimens ( n = 23) were divided into two groups, those from patients with preoperative chemoradiotherapy or untreated patients; six samples normal extraocular muscle used as a group. The presence heparanase‐1, patched, smoothened glioma‐associated oncogene homologue‐1 protein expression was determined 23 cases archival paraffin‐embedded...
Li, Yueyue MD, PhD; Yang, Xinji MD; Huang, Yifei Hei, Yan Wang, Liqiang Xiao, Lihua PhD Author Information
Three patients developed dacryoadenitis (DA) or lymphocytic pneumonitis before the diagnosis of hypophysitis (LyH). There were two previous reports concurrence DA and LyH. Our add support to idea that LyH are manifestations a systemic autoimmune disease. We suggest discovery should prompt imaging endocrine investigation
<title>Abstract</title> Background: Spheno-orbital meningioma (SOM) represents a unique variant of sphenoid wing meningiomas, distinguished by its propensity for bone infiltration and cranio-orbital involvement. SOM exhibits considerable incidence misdiagnosis recurrence. Purposes: To elucidate the clinical, radiological, pathological characteristics SOM. Methods: Review electronic medical records, histopathology, radiological images follow-up information 100 patients. Results: Of patients...
Control tissue is essential for ensuring the precision of semiquantitative analysis in back-table fluorescence imaging. However, there remains a lack agreement on appropriate selection control tissues. To evaluate imaging performance different normal tissues and identify optimal tissue, cohort 39 patients with orbital tumors were enrolled study. Prior to surgery, these received indocyanine green (ICG) following resection, 43 (34 adipose tissues, 3 skin periosteal muscle tissues) examined...
Abstract Precise resection of orbital tumors is a critically important but elusive issue. Fluorescence imaging in the near‐infrared II window (NIR‐II) holds potential to provide surgeons with real‐time identification for tumors. Here, first time, we evaluated feasibility and clinical value NIR‐II fluorescence tumor surgery. To establish method tumors, developed system indocyanine green (ICG) served as fluorescent contrast agent. Twenty‐two patients diagnosed scheduled standard‐of‐care...
A 33-year-old lady was referred to our clinic with a history of left upper eyelid swelling and difficulty open her eye for more than 4 years. Her globe in infero-nasal displacement, ocular movement not full, restriction every direction. No clinical sign including redness, pain or visual loss found on examination. Exophthalmometry confirmed 2 mm left-sided proptosis. Computed tomography (CT) imaging the orbit obtained axial coronal planes depicted an irregular heterogeneous soft-tissue...
BACKGROUND:Lacrimal gland pleomorphic adenoma (LGPA) is the most common clinically benign epithelial tumor of lacrimal and predominantly comprised cells interstitial components. At present, exact pathogenesis LGPA remains unclear. Previous research has indicated that occurrence may be related to excessive cell proliferation. MATERIAL AND METHODS:This study observed clinicopathological characteristics investigated tumorigenesis mechanism over-proliferation caused by imbalance between...
This report describes two young patients with osteolytic destruction in adjacent vertebral bodies along the intervertebral disc, and reveals its possible mechanism. A lateral radiograph CT scan displayed a giant cavity L4 body. An MRI or two-dimensional reconstruction same changes body lower endplate erosion L3 comprehensive preoperative evaluation did not identify specific cause of destruction. Both underwent anterior lumbar fusion surgery. The lesions were removed for histological...
Objective To study the cell membrane of T-lymphocytes in thyroid associated ophthalmopathy (TAO) by using atomic force microscopy (AFM). Methods Case-control study. Forty-two patients were selected as subjects, and divided into two groups: acute stage (18) stationary stage(24) ones on basis symptom. Ninety-two healthy persons normal groups. Dynal immunomagnetic beads isolation method was used to separate T cells. CD3+ chosen a surface molecule marker cells determine purity isolated....
Lymphoproliferative diseases (LPDs) of the ocular adnexa encompass majority orbital and include reactive follicular hyperplasia (RFH), atypical lymphoid (ALH), mucosa-associated tissue lymphoma (MALToma). Lymphoid follicles (LFs) are usually observed during histological examination LPDs. Currently, because there is a lack specific clinical signs diagnostic immunohistochemical biomarkers, it difficult for pathologists to distinguish MALToma from RFH ALH, which makes management these...
Objective To study the morphological representation of orbital tissue in thyroid associated ophthalmopathy. Methods It was a retrospective ease series. 138 specimens TAO( include 77 fat, 41 periosteum and 20 lacrimal gland tissue) were analyzed by light microscopy immunohistochemical staining. Results The notable hyperplasia fat found from 73 12 20. fibrous muscular metaplasia observed periosteum. Conclusions TAO is very important ubiquitous pathological changes. Study on prevent against...
Objective: To investigate the clinical features of patients who develop periorbital lipogranuloma after injection autologous fat. Methods: This retrospective case series included 18 developed a mass or swelling undergoing fat for facial augmentation. The patients’ medical records were reviewed history, radiologic findings, and treatment outcomes. Results: All women aged 24 to 50 years (mean, 31.6 years). Five (27.8%) involved both orbits. Presenting eye symptoms palpable (61.1%), eyelid...
Objective: To describe imaging signs of infraorbital nerve enlargement (IONE) and frontal (FNE) in orbital lymphoproliferative diseases (LPDs), to explore the diagnostic value differential role signs. Methods: A retrospective case series study. The data 222 cases (262 eyes) LPDs 95 (134 inflammatory pseudotumors (IPs) pathologically confirmed by Peking University People's Hospital Third Medical Center Chinese PLA General from January 2013 December 2018 were analyzed. lymphoma (including...