A5051546436- Dementia and Cognitive Impairment Research
- Stroke Rehabilitation and Recovery
- Neurobiology of Language and Bilingualism
- Parkinson's Disease Mechanisms and Treatments
- Amyotrophic Lateral Sclerosis Research
- Acute Ischemic Stroke Management
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Spatial Neglect and Hemispheric Dysfunction
- Family and Disability Support Research
- Memory Processes and Influences
- Psychological Well-being and Life Satisfaction
- Migraine and Headache Studies
- Cardiovascular Syncope and Autonomic Disorders
- Autism Spectrum Disorder Research
- Healthcare Technology and Patient Monitoring
- Pituitary Gland Disorders and Treatments
- Mitochondrial Function and Pathology
- Neurological Disorders and Treatments
- Memory and Neural Mechanisms
- Alzheimer's disease research and treatments
- Hip and Femur Fractures
- Ginkgo biloba and Cashew Applications
- Psychological and Temporal Perspectives Research
- Retinal Imaging and Analysis
University Hospitals Plymouth NHS Trust
2009-2024
University of Plymouth
2012-2024
Derriford Hospital
2009-2023
Peninsula College of Medicine and Dentistry
2015
Plymouth Hospital
2014
University of Nottingham
2004
Nottingham City Hospital
2000
Marymount University
1998
Motor neuron disease (MND) is a fatal, progressive neurodegenerative that causes weakening and wasting of limb, bulbar, thoracic abdominal muscles. Clear evidence-based guidance on how psychological distress should be managed in people living with MND (plwMND) lacking. Acceptance Commitment Therapy (ACT) form therapy may particularly suitable for this population. However, to the authors' knowledge, no study date has evaluated ACT plwMND. Consequently, primary aim uncontrolled feasibility was...
Abstract Introduction Ensuring reliable administration and reporting of cognitive screening tests are fundamental in establishing good clinical practice research. This study captured the rate type errors practice, using Addenbrooke's Cognitive Examination‐III (ACE‐III), then reduction error a computerized alternative, ACEmobile app. Methods In 1, we evaluated ACE‐III assessments completed National Health Service (NHS) clinics ( n = 87) for administrator error. 2, were their ability to...
It is important to recognise that migraine a 'biological' and not 'psychological' entity. However, psychological factors can be involved in 4 different ways:- 1) Migraines triggered by stressors; 2) Severe itself cause of significant stress which can, turn, exacerbate the problem; 3) Even if significantly genesis headache, pain management techniques help people cope with their more effectively; 4) Longitudinal data demonstrate complex bidirectional association between mood disorders...
Purpose: The aims were to describe the functional abilities of and services provided stroke patients not admitted hospital a year after investigate factors associated with receiving rehabilitation services. Method: A cohort who had been notified by general practitioners. Patients assessed at month on measures impairment disability. received was recorded. There 124 GP's hospital. Of these 70 both one stroke. Results: showed persistent impaired levels disability stroke, as measured Extended...
Autosomal recessive disorders affecting pyridoxine (vitamin B6) metabolism are a rare but well-recognized cause of neonatal seizures. Antiquitin deficiency, caused by mutations in ALDH7A1, is disorder the lysine degradation pathway causing accumulation an intermediate that complexes with pyridoxal phosphate. Reports long-term follow-up pyridoxine-dependent seizures (PDS) remain scarce and prognostic information varied. We report case PDS 47-year-old lady who originally presented shortly...
Post stroke anxiety is associated with reduced quality of life, worse rehabilitation outcomes and poor social functioning in survivors. Despite its clinical relevance, there are a lack screening tools to identify post-stroke anxiety. The Hospital Anxiety Depression Scale (HADS-A) Geriatric Inventory (GAI) the only self-report test for validated patients. However, both these measures have limitations their utility, length time administer cost purchase. This study aimed assess classiciation...
This article compares the outcomes and services provided for stroke patients who had not been admitted to hospital with those less than 1 month. Patients were assessed month year after on measures of impairment disability. The rehabilitation they received was recorded. There 243 notified by GPs whom 124 hospital. Of these, 93 at 76 stroke. 97 hospital, 86 65 Comparison between community showed no significant difference Barthel Index, but a Extended Activities Daily Living scale few...
<b><i>Introduction:</i></b> Cognitive screening measures are an established part of a dementia assessment and often include subjective difficulties, e.g., Everyday Memory Questionnaire (EMQ), informant-rated difficulty, Cambridge Behavioural Inventory – Revised (CBI-R), objective cognitive assessments like Addenbrooke’s Examination (ACE-III). While these have validity for the purpose diagnosing dementia, in clinical practice they used outside their evidence base...
Abstract Background: Motor neuron disease (MND) is a progressive, fatal, neurodegenerative condition that affects motor neurons in the brain and spinal cord, resulting loss of ability to move, speak, swallow breathe. Acceptance commitment therapy (ACT) an acceptance-based behavioural may be particularly beneficial for people living with MND (plwMND). This qualitative study aimed explore plwMND’s experiences receiving adapted ACT, tailored their specific needs, therapists’ delivering it....
Introduction: There is increasing need to be able reliably diagnose Alzheimer’s Disease (AD) in the NHS. With an aging population, number of patients expected have dementia predicted double by 2030 (www.dementia2010.org). Despite developments NHS memory clinic services, currently, 50% with may never receive a formal diagnosis and many do not until they are moderate/severe stages. develop measures assess that valid, sensitive, reliable and, importantly, fit for use routine care. The demand on...
Objective To establish a consensus on the structure and process of healthcare services for patients with concussion in England to facilitate better quality patient outcome. Design This study followed modified Delphi methodology five phases: participant identification, item development, two rounds voting meeting finalise statements. The predefined threshold agreement was set at ≥70%. Setting Specialist outpatient services. Participants Members UK Head Injury Network were invited participate....
Event Abstract Back to MyWordTrainer: improving word retrieval using app-based therapy in semantic variant Primary Progressive Aphasia Sharon Savage1*, Craig Newman2, Rupert Noad3 and Adam Zeman4 1 Department of Psychology, College Life Environmental Sciences, University Exeter, United Kingdom 2 Peninsula Medical School, Faculty Medicine Dentistry, Plymouth, 3 Derriford Hospital, 4 The Institute Health Research, Background aims. Difficulty with naming is one the most striking features...
Background In order to facilitate neuroprotective trials in Parkinson's disease (PD), there is a need for improved means of early detection and measuring progression. Computerised assessment may afford easier increasingly accurate administration motor cognitive tests, as well measurement indices not readily accessible with standard testing paradigms. Aim To develop validate iPad-based measures PD. Method 62 PD patients 42 age-matched controls completed traditional iPad versions the Trail...
Administration and scoring errors are commonly observed in the assessment of cognitive decline elderly. This is case both clinical practice multi-centre research trials. Cognitive assessments often require administrator to have internalized a complex administration manual be able apply this invivo during testing sessions where demands on can high. Scoring requires knowledge psychometric theory reliable mental arithmetic skills. project developed evaluated an iPad based tool support use...
The current gold standard for assessment and monitoring of Parkinson9s disease (PD) is the unified PD rating scale (UPDRS). While a useful evaluation tool, its application research limited by need an experienced rater, intra inter-rater reliability 5-point scale. UPDRS time-consuming with specific motor taking >15 minutes to administer. Rapid, objective tools are needed aid utility. A finger-tapping app (PD-Tap), developed use on iPod Touch, was used test finger tapping performance in 16...
Introduction Cognitive assessments, such as the Addenbrooke's Examination (ACE-III) and Montreal Assessment (MoCA), have been modified for administration using tablet computers. While this offers important advantages practice, it may also threaten test validity. The current study sought to whether administering visuospatial writing tests a (finger or stylus drawing), would demonstrate equivalence traditional pencil paper on ACEmobile.Method This recruited 26 participants with Alzheimer's...
<sec> <title>BACKGROUND</title> Cognitive screening is common practice in efforts to identify Alzheimer’s dementia the early stages. The need for reliable and accurate assessment critical, at this stage, avoid distress or missed opportunities support people with developing health needs. Administrator errors are observed be both significant when clinicians deliver cognitive tools clinical contexts, often as a result of complicated rules mental arithmetic. Addenbrooke’s Examination-III one...