A5005349013- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sarcoidosis and Beryllium Toxicity Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Medical Imaging and Pathology Studies
- Neonatal Respiratory Health Research
- Lung Cancer Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Eosinophilic Disorders and Syndromes
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Inflammatory Biomarkers in Disease Prognosis
- Occupational and environmental lung diseases
- Eosinophilic Esophagitis
- SARS-CoV-2 and COVID-19 Research
- Systemic Sclerosis and Related Diseases
- Radiomics and Machine Learning in Medical Imaging
- Pleural and Pulmonary Diseases
- Lung Cancer Treatments and Mutations
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- Pregnancy and preeclampsia studies
- Occupational exposure and asthma
University of Patras
2020-2024
National and Kapodistrian University of Athens
2016-2024
University General Hospital Attikon
2024
University of South Florida
2023-2024
General University Hospital of Patras
2020-2024
Oregon Medical Research Center
2024
University of Pittsburgh
2024
Communities In Schools of Orange County
2024
New York Proton Center
2024
Lindsay Unified School District
2024
Abstract Background and Objective There remains a paucity of large databases for patients with idiopathic pulmonary fibrosis (IPF) lung cancer. We aimed to create European registry. Methods This was multicentre, retrospective study across seven countries between 1 January 2010 18 May 2021. Results identified 324 cancer among 3178 IPF (prevalence = 10.2%). By the end 10 year‐period following diagnosis, 26.6% alive had been diagnosed Patients experienced increased risk all‐cause mortality than...
Abstract Background Idiopathic Pulmonary Fibrosis (IPF) represents a chronic lung disease with unpredictable course. Methods We aimed to investigate prognostic performance of complete blood count parameters in IPF. Treatment-naïve patients IPF were retrospectively enrolled from two independent cohorts (derivation and validation) split into subgroups (high low) based on median baseline monocyte red cell distribution width (RDW). Results Overall, 489 cohort: 300, validation 189) analyzed. In...
Mediastinal lymph node enlargement is prevalent in patients with idiopathic pulmonary fibrosis (IPF). Studies investigating whether this phenomenon reflects specific immunologic activation are lacking.Programmed cell death-1 (PD-1)/ programmed death ligand-1 (PD-L1) expression mediastinal nodes and lung tissues was analyzed. PD-1, PD-L1 mRNA measured tracheobronchial of mice following bleomycin-induced injury on day 14. Finally, the effect PD-1 inhibitor, pembrolizumab, investigated.We...
MCEMP1 is highly expressed in circulating classical monocytes and alveolar macrophages IPF, regulated by TGFβ, participates the chemotaxis, adhesion, migration of modulating effect TGFβ RHO activity.
First, to evaluate and compare the performance of routine ultrasonographic estimated fetal weight (EFW) abdominal circumference (AC) at 31 + 0 33 6 35 36 weeks' gestation in prediction a large-for-gestational-age (LGA) neonate born ≥ 37 gestation. Second, assess additive value growth velocity between 32 EFW for LGA neonate. Third, define predictive different cut-offs on ultrasound examination Fourth, propose two-stage strategy identifying pregnancies with fetus that may benefit from...
Pirfenidone is an antifibrotic compound able to slow down disease progression in patients with idiopathic pulmonary fibrosis (IPF).To investigate the safety and efficacy of pirfenidone IPF a real-life setting.This was multicenter, retrospective, real-life, observational study for receiving pirfenidone.We identified 92 pirfenidone. Eighty (70 males 10 females, mean age ± SD: 68.1 + 7.5, %FVC SD = 74.9 17.2, %DLCO 48.1 16.9) were included analysis. Skin-related (25%) gastrointestinal (17.5%)...
Introduction: Depression is prevalent in patients with Idiopathic Pulmonary Fibrosis (IPF). The impact of depression on quality life and its correlation disease severity IPF has not been thoroughly evaluated prospective studies. Patients Methods: Between 2016 2017, we prospectively enrolled 101 (80 male, mean age (years) +SD: 70.8+8.1) (mean GAP score+SD: 4.7+1.8) without previous diagnosis depression. Depressive symptoms were Beck's inventory-II (BDI-II). Disease was pulmonary function...
Currently there is major lack of agreement on the diagnostic and therapeutic management patients with idiopathic pulmonary fibrosis (IPF) lung cancer. Our aim was to identify variations in strategies across different institutions provide rationale for a consensus statement this issue.This joint-survey by European Respiratory Society (ERS) Assemblies 8, 11 12. The survey consisted 25 questions.Four hundred ninety-four (n=494) physicians from 68 countries five continents responded survey....
<b><i>Introduction:</i></b> During the first COVID-19 wave, a considerable decline in hospital admissions was observed worldwide. <b><i>Aim:</i></b> This retrospective cohort study aimed to assess if there were any changes number of patients hospitalized for respiratory diseases Greece during COVID-19 wave. <b><i>Methods:</i></b> In present study, we evaluated disease hospitalization rates across 9 tertiary hospitals...
Post-acute sequelae of COVID-19 seem to be an emerging global crisis. Machine learning radiographic models have great potential for meticulous evaluation post-COVID-19 interstitial lung disease (ILD).In this multicenter, retrospective study, we included consecutive patients that had been evaluated 3 months following severe acute respiratory syndrome coronavirus 2 infection between 01/02/2021 and 12/5/2022. High-resolution computed tomography was through Imbio Lung Texture Analysis 2.1.Two...
Obesity and cancer represent two pandemics of current civilization, the progression which has followed parallel trajectories.To time, thirteen types malignancies have been recognized as obesity-related cancers, including breast (in postmenopausal women), endometrial, ovarian cancer.Pathophysiologic mechanisms that connect entities include insulin resistance, adipokine imbalance, increased peripheral aromatization estrogen levels, tissue hypoxia, disrupted immunity in cellular milieu.Beyond...
Mitogen-activated protein kinase (MAPK) phosphatase 5 (MKP-5) is a member of the dual-specificity family tyrosine phosphatases that negatively regulates p38 MAPK and JNK. MKP-5-deficient mice exhibit improved muscle repair reduced fibrosis in an animal model muscular dystrophy. Here, we asked whether effects MKP-5 on extend to other tissues. Using bleomycin-induced pulmonary fibrosis, found were protected from development lung expressed levels hydroxyproline fibrogenic genes, displayed...