A5065428275- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Advanced battery technologies research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Supercapacitor Materials and Fabrication
- Extracellular vesicles in disease
- Advanced Battery Materials and Technologies
- Advanced Battery Technologies Research
- RNA Research and Splicing
- Atherosclerosis and Cardiovascular Diseases
- Insect and Arachnid Ecology and Behavior
- Immune Cell Function and Interaction
- Animal Behavior and Reproduction
- Ubiquitin and proteasome pathways
- Surface Chemistry and Catalysis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Advancements in Battery Materials
- Plant and animal studies
- Neuropeptides and Animal Physiology
- Web visibility and informetrics
- Reproductive System and Pregnancy
- T-cell and B-cell Immunology
- Mesenchymal stem cell research
- melanin and skin pigmentation
Central South University
2015-2024
Third Xiangya Hospital
2015-2024
Xiangya Hospital Central South University
2023
Zhongnan Hospital of Wuhan University
2017-2021
Wuhan University
2017-2021
University of Pittsburgh
2019-2021
Hubei University
2020
Second Affiliated Hospital of Fujian Medical University
2019
Fujian Medical University
2019
Chengdu University
2012
Biocompatible devices are widely employed in modernized lives and medical fields the forms of wearable implantable devices, raising higher requirements on battery biocompatibility, high safety, low cost, excellent electrochemical performance, which become evaluation criteria toward developing feasible biocompatible batteries. Herein, through conducting implantation tests leakage scene simulations New Zealand rabbits, zinc sulfate electrolyte is proved to exhibit biosecurity turns out be one...
Wearable and implantable electronics are standing at the frontiers of science technology, driven by increasing demands from modernized lifestyles. Zinc-based batteries (ZBs) regarded as ideal energy suppliers for these biocompatible electronics, but corresponding biocompatibility validation is still in initial stage. Meanwhile, complicated working conditions some extreme electrolyte environments raise strict challenges, leaving less choices safe ZBs. Toward higher operating stability...
In the pursuit of convenient and healthy lives, human body electronic devices with interactive, medical, communication functions have been gradually developed, propelling research into high-safety aqueous batteries as energy hubs. Despite extensive progress, application in is still at proof-of-concept stage. this Focus Review, we comprehensively summarize design strategies advances rational coupling electrochemical properties mechanical properties, degradability, biocompatibility for...
Abstract Zinc metal batteries (ZMBs) hold great promise for large‐scale energy storage in renewable solar and wind farms. However, their widespread application is hindered by poor stability unsatisfactory low‐temperature performance, attributed to issues such as dendrite formation, strong Zn 2+ ‐H 2 O coordination, electrolyte freezing. Herein, a deep eutectic sol (DESE) proposed mixing SiO nanoparticles with solution composed of 1,3‐dioxolane (DOL) Zn(ClO 4 ) ·6H stable ZMBs. By...
Long non-coding RNAs (LncRNAs) have been associated with several types of cancer. However, little is known about their role in lung adenocarcinoma (LUAD).LINC00968 was significantly differentially expressed LUAD tissues. Downregulated LINC00968 clinicopathological features LUAD. inhibited cell growth and metastasis by regulating the Hippo signaling pathway We demonstrated that acts as a ceRNA to consume miR-21-5p, enhancing accumulation SMAD7, miR-21-5p target.LINC00968 limits progression...
Despite the role of donor-specific antibodies (DSAs) in recognizing major histocompatibility complex (MHC) antigens and mediating transplant rejection, how where recipient B cells lymphoid tissues encounter donor MHC remains unclear. Contrary to dogma, we demonstrated here that migration leukocytes out skin or heart allografts is not necessary for T cell allosensitization mice. We found mouse cardiac human grafts release cell-free via extracellular vesicles (EVs) are captured by subcapsular...
Efficient Ca2+ flux induced during cognate T cell activation requires signaling the receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs). cells express neurokinin-1 (NK1R), a GPCR that mediates in excitable non-excitable cells. However, role of NK1R TCR remains unknown. We show its agonists, neuropeptides substance P hemokinin-1, co-localize within immune synapse Simultaneous stimulation is necessary for efficient Ca2+-dependent sustains survival activated helper 1 (Th1) Th17...
Abstract Long noncoding RNAs (lncRNAs) are linked to tumor development and progression. The aim of this study was determine the prognostic significance biological role LINC01116 in head neck squamous cell carcinoma (HNSCC). We identified 21 aberrantly expressed lncRNAs specific HNSCC that were common two microarray datasets. highly overexpressed tissues correlated shorter overall survival relapse‐free duration, as analyzed by online Gene Expression Profiling Interactive Analysis platform....
Abstract Donor‐derived adipose‐derived mesenchymal stem cells (ADMSCs) dampen the alloimmune response and exosomes are reported to have biological activity similar their parent cells. Here, we investigated roles of from donor‐derived ADMSCs (ADMSC‐exo) in vascularized composite allotransplantation (VCA). Brown Norway‐to‐Lewis rat hindlimb transplantations were intravenously treated with either exosome or phosphate‐buffered saline, combined a short course immunosuppression. We established...
Background: Recent findings have shown long non-coding RNAs (lncRNAs) are dysregulated in a variety of cancer cells.In this report, we investigate the effect T-cell leukemia lymphoma 6 (TCL6) on paclitaxel (PTX)-induced apoptosis Renal cell carcinoma (RCC) cells.Methods: Expression levels TCL6 RCC tissues were analyzed via The Cancer Genome Atlas (TCGA) and Gene Omnibus (GEO) datasets.Fluorescence situ hybridization (FISH) was performed to detect expression cells.Two pairs lines used:...
The roles of long noncoding RNA FOXD2 adjacent opposite strand 1 (FOXD2-AS1) in oral squamous cell carcinoma (OSCC) remain largely unknown. Here, the Atlas Noncoding RNAs Cancer online database was utilized to analyze expression and clinical significance FOXD2-AS1 OSCC. Then, proliferation FOXD2-AS1-silenced OSCC cells (CAL-27) assessed by MTT clone formation experiments. FOXD2-AS1-coexpressed genes were enriched analyzed via circlncRNAnet Metascape tools. Finally, key molecules signal...
Abstract A number of strategies that divert attacks visually guided predators, such as birds, have evolved multiple times in animals. Detritus web decorations built by certain orb‐web spider species are thought to deflect avian predator away from spiders and towards their decorations. Still, empirical evidence for this function its adaptive significance is lacking. The spider, Cyclosa monticola , adorns using a linear detritus decoration consisting moults, egg sacs, prey remains leaf...
Background/Aims: Zinc finger protein 667 (ZNF667) is a member of C2H2 zinc family. For the first time, we aim to analyze expression pattern ZNF667 in hepatocellular carcinoma (HCC) tissues; explore its role HCC tumorigenesis. Methods: Immuno-histochemistry was carried out characterize paraffin-embedded samples. The relationship between and clinical, pathological data patients were analyzed. Human normal hepatocyte cells LO2 over expressing (LO2-ZNF667 cells), depleted HepG2 (HepG2-shZNF667...
Abstract Endothelium, the inner cellular lining of blood vessels, has an important role in regulation physiological processes and its dysfunction may initiate cardiovascular complications. Previous investigations have revealed that dietary docosahexaenoic acid (DHA) is related to a lower possibility disease mortality. Until now, molecular mechanisms biological activities DHA remain largely unknown. MicroRNAs (miRNAs) play vital regulating gene expression. Thus, we aimed investigate whether...