A5100639425- Plant Molecular Biology Research
- Circular RNAs in diseases
- Plant-Microbe Interactions and Immunity
- Cancer-related molecular mechanisms research
- Phytoplasmas and Hemiptera pathogens
- Plant Virus Research Studies
- MicroRNA in disease regulation
- Plant Gene Expression Analysis
- Plant Pathogens and Fungal Diseases
- Plant Stress Responses and Tolerance
- Fungal and yeast genetics research
- Mycotoxins in Agriculture and Food
- Plant Disease Resistance and Genetics
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Plant nutrient uptake and metabolism
- Weed Control and Herbicide Applications
- GABA and Rice Research
- RNA and protein synthesis mechanisms
- Viral Infections and Immunology Research
- Plant Pathogenic Bacteria Studies
- Enzyme Production and Characterization
- Medicinal Plants and Neuroprotection
- Legume Nitrogen Fixing Symbiosis
- Chromosomal and Genetic Variations
Jiangsu Academy of Agricultural Sciences
2014-2024
Jiangsu University
2022-2024
Soochow University
2020-2022
Zhangjiagang First People's Hospital
2020-2022
South China Agricultural University
2019-2022
China Medical University
2020-2021
Hainan Medical University
2021
Wuhan Dongxihu District People Hospital
2021
Nanjing Medical University
2018-2020
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2020
Abstract Background Ribosomes are essential ribonucleoprotein complexes that engaged in translation and thus indispensable for growth. Arabidopsis thaliana ribosomes composed of 80 distinct ribosomal proteins (RPs), each which is encoded by two to seven highly similar paralogous genes. Little information available on how RP genes respond a shortage mineral nutrients such as phosphate (Pi) or iron (Fe). In the present study, expression differential accumulation RPs upon Pi Fe deficiency roots...
Background MicroRNAs (miRNAs) are noncoding RNAs of approximately 21 nt that regulate gene expression in plants post-transcriptionally by endonucleolytic cleavage or translational inhibition. miRNAs play essential roles numerous developmental and physiological processes many them conserved across species. Extensive studies have been done a few model plants; however, less is known about the diversity these regulatory peanut (Arachis hypogaea L.), one most important oilseed crops cultivated...
Long Noncoding-RNAs (LncRNAs) are known to be involved in some biological processes, but their roles plant-virus interactions remain largely unexplored. While circular RNAs (circRNAs) have been studied animals, there has yet extensive research on them a plant system, especially tomato-tomato yellow leaf curl virus (TYLCV) interaction.
Drought and Verticillium wilt disease are two main factors that limit cotton production, which necessitates the identification of key molecular switch to simultaneously improve resistance dahliae tolerance drought stress. R2R3-type MYB proteins could play such a role because their conserved functions in plant development, growth, metabolism regulation, however, till date gene conferring desired both biotic abiotic stresses has not been found cotton. Here, we describe GhMYB36, encoding...
Cold stress is known to influence tomato growth, development, and yield. In this study, we analyzed the germination of seeds treated with exogenous glycine betaine (GB) at a low temperature (14 °C). The results showed that cold inhibited seed germination, pretreatment GB reduced inhibition enhanced rate (GR), index (GI), viability temperatures. Analysis gene expression metabolism revealed positively regulated endogenous hormone gibberellin (GA) content negatively abscisic acid (ABA) content,...
Salt stress significantly impedes plant growth and the crop yield. This study utilized de novo transcriptome assembly ribosome profiling to explore mRNA translation's role in rice salt tolerance. We identified unrecognized translated open reading frames (ORFs), including 42 upstream transcripts 86 unannotated transcripts. A noteworthy discovery was of a small ORF, Ospep5, conferring Overexpression Ospep5 plants increased tolerance, while its absence led heightened sensitivity. hypothesis...
Aim: We aimed to explore the roles of circRNAs in gastric cancer. Materials & methods: The dysregulated and miRNAs were identified using data from Gene Expression Omnibus. specifically selected explored. Survival analysis was performed Cancer Genome Atlas. Results: 68 51 miRNAs. found that hsa_circ_0000993 inhibited migration, invasion proliferation cancer cells could act as a miRNA sponge for miR-214-5p but did not modulate expression its parental gene, ATL2. showed patients with lowly...
Salmonella enterica subsp. serovar Typhimurium infections continue to be a significant public health threat worldwide. The aim of this study was investigate antibiotic resistance among 147 S. isolates collected from patients in Henan, China 2006 2015.147 were March November 2015 Henan Province, China. Antimicrobial susceptibility testing performed, and the resistant genes ciprofloxacin, cephalosporins (ceftriaxone cefoxitin) azithromycin detected sequenced. Clonal relationships assessed by...
A high-resistant starch (RS) and low-glutelin diet is beneficial for the health of patients with diabetes kidney diseases. Rice an important food crop worldwide. Previous studies have demonstrated that downregulating expression rice branching enzyme IIb (SBEIIb) affected composition structure starch. However, there has been no report about generating loss-of-function mutants SBEIIb using cultivars as recipients. In this study, we adopted a CRISPR/Cas9 system to induce site-specific mutations...
Introduction: Human malignant melanoma (MM) is a highly tumor of cutaneous melanocytes with fast progression. We investigated the cellular effects pyrroline-5-carboxylate reductase 1 (PYCR1) in MM cell lines, A375 and M14. Methods: Cell Counting Kit-8 assay, transwell flow cytometry analysis were performed to evaluate proliferation, migration apoptosis respectively. To gain more insight into role PYCR1 growth, we analyzed AKT phosphorylation level PYCR1-specific siRNA (siPYCR1) negative...
Abstract Hepatic stellate cells (HSCs) and cancer‐associated fibroblasts (CAFs) play critical roles in liver fibrosis hepatocellular carcinoma (HCC). MyD88 controls the expression of several key modifier genes tumorigenesis; however, whether how myofibroblasts contributes to development fibrosis‐associated cancer remains elusive. Here, we used an established hepatocarcinogenesis mouse model involving apparent fibrogenesis which was selectively depleted myofibroblasts. Myofibroblast...
The basic leucine zipper (bZIP) is a transcription factor family that plays critical roles in abiotic and biotic stress responses as well plant development growth. A comprehensive genome-wide study Liriodendron chinense was conducted to identify 45 bZIP factors (LchibZIPs), which were divided into 13 subgroups according the phylogenetic analysis. Proteins same subgroup shared similar gene structures conserved domains, total of 20 motifs revealed LchibZIP proteins. Gene localization analysis...
The microRNAs (miRNAs) are a new class of small nonprotein-coding RNAs that have been identified to regulate gene expression at the post-transcriptional level by targeting mRNAs for degradation or inhibiting protein translation. Until now, thousands miRNAs in many plants species. However, only 23 reported from microRNA database Chinese cabbage ( Brassica rapa subsp. pekinensis ), one most widely cultivated vegetables China and East Asia. In present study, 168 potential miRNAs, derived 22 EST...
Lysin-motif (LysM) receptor kinases (LYKs) play essential roles in recognition of chitin and activation defense responses against pathogenic fungi model plants Arabidopsis rice. The function LYKs non-model remains elusive. In present work, we found that the transcription two from cotton, Gh-LYK1 Gh-LYK2, were induced after Verticillium dahliae (V. dahliae) infection. VIGS based silencing Gh-LYK2 cotton showed compromises resistance to V. dahliae. As putative pattern receptors, both are...
Weeds present a significant challenge to agricultural productivity, and acetyl-CoA carboxylase (ACCase)-inhibiting herbicides have proven be effective in managing weed populations rice fields. To develop ACCase-inhibiting herbicide-resistant rice, we generated mutants of ACCase (OsACC) featuring Ile-1792-Leu or Gly-2107-Ser substitutions through ethyl methyl sulfonate (EMS) mutagenesis. The mutant displayed cross-resistance aryloxyphenoxypropionate (APP) phenylpyrazoline (DEN) herbicides,...
While frequently used herbicides display limited efficacy against herbicide-resistant weeds, it becomes imperative to explore novel that ensure both effective weed management and environmental safety. Though 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitory like mesotrione are prevalent in maize management, their integration into rice production is hindered due the inherent sensitivity of HPPD (