A5034926750- Bacterial biofilms and quorum sensing
- Bacterial Genetics and Biotechnology
- Antibiotic Resistance in Bacteria
- Perovskite Materials and Applications
- Advanced Photocatalysis Techniques
- Vibrio bacteria research studies
- Advanced battery technologies research
- Covalent Organic Framework Applications
- Supercapacitor Materials and Fabrication
- Electronic and Structural Properties of Oxides
- Polyoxometalates: Synthesis and Applications
- Fuel Cells and Related Materials
- Advanced Battery Materials and Technologies
- Microbial Applications in Construction Materials
- Microbial Inactivation Methods
- Medical Image Segmentation Techniques
- Electrocatalysts for Energy Conversion
- Environmental Impact and Sustainability
- Retinal Imaging and Analysis
- Rings, Modules, and Algebras
- Bacterial Identification and Susceptibility Testing
- Advanced Topics in Algebra
- Catalytic Processes in Materials Science
- Agriculture Sustainability and Environmental Impact
- Antibiotics Pharmacokinetics and Efficacy
State Key Laboratory of Crystal Materials
2023-2024
Shandong University
2023-2024
State Key Laboratory of Medicinal Chemical Biology
2022-2023
Nankai University
2022-2023
Nanjing University of Information Science and Technology
2022
Anhui University
2022
Shanghai Open University
2020
Shanghai University
2020
Severe poisonousness and prolonged instability existing in organic-inorganic lead-based perovskite are two matters seriously hindering its potential future application photocatalysis. Therefore, it is particularly important to explore ecology-friendly, air-stable highly active metal-halide perovskites. Herein, a new stable lead-free Cs2 SnBr6 decorated with reduced graphene oxide (rGO), synthesized employed the photocatalytic organic conversion. The as-prepared ultrastable, exhibiting no...
Environmental metabolites and metabolic pathways significantly influence bacterial pathogenesis interspecies competition. We previously discovered that a mutation in the triosephosphate isomerase gene, tpiA , Pseudomonas aeruginosa led to defective type III secretion increased susceptibility aminoglycoside antibiotics. In this study, we found enhances Las quorum sensing system due reduced translation of negative regulator RsaL. Further investigations demonstrated an upregulation CspC, CspA...
Abstract Pseudomonas aeruginosa is capable of causing acute and chronic infections in various host tissues, which depends on its abilities to effectively utilize host-derived nutrients produce protein virulence factors toxic compounds. However, the regulatory mechanisms that direct metabolic intermediates towards production compounds are poorly understood. We previously identified a PvrA controls genes involved fatty acid catabolism by binding palmitoyl-coenzyme A (CoA). In this study,...
As a major agricultural country, the comprehensive accounting of dynamics and composition carbon footprint crops in China will provide decision-making basis for environmental management green development whole process crop production system China. To investigate spatiotemporal China, life cycle-based approach was used to evaluate per unit area (CFA) yield (CFY) eight period 1990 2019. Our results showed that CFA all an increasing trend with time before 2016 but slowly decreased afterward,...
Pseudomonas aeruginosa is an opportunistic human pathogen capable of causing a variety acute and chronic infections. Its type III secretion system (T3SS) plays critical role in pathogenesis during infection. ExsA master regulator that activates the expression all T3SS genes. Transcription exsA driven by two distinct promoters, its own promoter P operon exsC . Here, combination with DNA pull-down assay mass spectrometric analysis, we found histone-like nucleoid-structuring (H-NS) family...
The small size lead-free Cs 3 Bi 0.6 Sb 1.4 Br 9 solid-solution spatially confined in MCM-41 molecular sieve shows an outstanding performance for photocatalytic CO 2 reduction to CO.
Pseudomonas aeruginosa is a ubiquitous pathogenic bacterium that can adapt to variety environments. The ability effectively sense and respond host local nutrients critical for the infection of P. aeruginosa. However, mechanisms employed by remain be explored. CspA family proteins are RNA binding involved in gene regulation. We previously demonstrated protein CspC regulates type III secretion system response temperature shift. In this study, we found quorum-sensing (QS) systems repressing...
NrtR is a Nudix-related transcriptional regulator that distributed among diverse bacteria and plays an important role in modulating bacterial intracellular NAD homeostasis. Previously, we showed influences the T3SS expression pathogenesis of Pseudomonas aeruginosa demonstrated mediates regulation through cAMP/Vfr pathway. In present study, found mutation nrtR gene leads to upregulation Hcp secretion island-I type VI system (H1-T6SS). Further analysis revealed results regulatory RNAs...
Multidrug-resistant (MDR) Pseudomonas aeruginosa poses a great challenge to clinical treatment. In this study, we characterized ST768 MDR P. strain, Pa150, that was isolated from diabetic foot patient. The minimum inhibitory concentration (MIC) assay showed Pa150 resistant almost all kinds of antibiotics, especially aminoglycosides. Whole genome sequencing revealed multiple antibiotic genes on the chromosome and 437-Kb plasmid (named pTJPa150) harbors conjugation-related genes. A conjugation...
Pseudomonas aeruginosa is an important opportunistic pathogen capable of causing variety infections in humans. The type III secretion system (T3SS) a critical virulence determinant P . the host infections. Expression T3SS regulated by ExsA, master regulator that activates expression all known genes. exsA gene controlled at both transcriptional and posttranscriptional levels. Here, we screened transposon (Tn5) insertional mutant library found rplI , coding for ribosomal large subunit protein...
Pseudomonas aeruginosa is an important nosocomial pathogen which frequently becomes resistant to most antibiotics used in chemotherapy, resulting treatment failure among infected individuals. Although the evolutionary trajectory and molecular mechanisms for becoming β-lactam have been well established P. aeruginosa, basis of reversion from susceptible largely unexplored. In this study, we investigated by a ceftazidime-resistant clinical strain converted ceftazidime-susceptible isolate under...
Medical image segmentation based on deep learning is a central research issue in the field of computer vision. Many existing networks can achieve accurate using fewer data sets. However, they have disadvantages such as poor network flexibility and do not adequately consider interdependence between feature channels. In response to these problems, this paper proposes new de-normalized channel attention network, which uses an improved residual block structure module for sophisticated vessels....
Although 2D π-d conjugated metal-organic frameworks (MOFs) exhibit high in-plane conductivity, the closely stacked layers result in low specific surface area and difficulty mass transfer diffusion. Hence, a conductive 3D MOF Fe
Pseudomonas aeruginosa is a ubiquitous pathogen that causes wide range of acute and chronic infections. Ciprofloxacin, one the first-line fluoroquinolone class antibiotics, commonly used for treatment P. However, ciprofloxacin-resistant increasingly reported worldwide, making difficult. To determine resistance-related mutations, we conducted an experimental evolution using previously identified clinical isolate, CRP42. The evolved mutants could tolerate 512-fold higher concentration...
The sustainable reduction of CO2 to chemical fuels through photocatalysis is a promising research direction. However, most photocatalysts still face the issues narrow light absorption, small specific surface area, and poor charge separability. Herein, Cs3Bi2xSb2-2xBr9 (CBSB-X) solid solutions with good visible absorption are successfully prepared. Moreover, spatially confined growth CBSB-X in MCM-41 molecular sieve can obtain small-sized nanoparticles. MCM-41@CBSB-X samples large area...
Inspired by the work of Wang and Zhou [4] for Rota-Baxter algebras, we develop a cohomology theory systems justify it interpreting lower degree groups as formal deformations abelian extensions systems. A further study on an $L_\infty$-algebra structure associated to this will be given in subsequent paper.