A5013287570- Vitamin C and Antioxidants Research
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- Mesenchymal stem cell research
- Vitamin D Research Studies
- Muscle Physiology and Disorders
- Nanoparticles: synthesis and applications
- Neuroscience and Neuropharmacology Research
- Cardiac pacing and defibrillation studies
- Trace Elements in Health
- Electrospun Nanofibers in Biomedical Applications
- Glutathione Transferases and Polymorphisms
- Enzyme function and inhibition
- Intestinal and Peritoneal Adhesions
- Alzheimer's disease research and treatments
- Vitamin K Research Studies
- Advancements in Transdermal Drug Delivery
- Parkinson's Disease Mechanisms and Treatments
- Cardiovascular Function and Risk Factors
- Environmental Toxicology and Ecotoxicology
- Spinal Cord Injury Research
- Genetics, Aging, and Longevity in Model Organisms
- Lipid Membrane Structure and Behavior
- Heart Failure Treatment and Management
- Nanoparticle-Based Drug Delivery
University of Minho
2018-2023
Hospital da Luz
2023
Hospital Pedro Hispano
2023
University of Coimbra
2016-2018
University of Lisbon
2003-2014
UCLouvain
2002
Abstract Adipose tissue‐derived stem cells (ASCs) have been shown to assist regenerative processes after spinal cord injury (SCI) through their secretome, which promotes several mechanisms, such as inducing axonal growth, reducing inflammation, promoting cell survival, and vascular remodeling, thus ultimately leading functional recovery. However, while systemic delivery (e.g., i.v. [intravenous]) may cause off‐target effects in different organs, the local administration has low efficiency...
Colorectal cancer (CRC) is continuously classified as one of the most incidental and mortal types worldwide. The positive outcomes conventional chemotherapy are frequently associated with high toxicity, which often leads to suspension treatment. Growing evidences consider use pharmacological concentrations ascorbic acid (AA), better known vitamin C, in treatment cancer. AA a clinical context essentially related adoption new therapeutic strategies based on combination regimens, where plays...
Parkinson's disease (PD) is the second most common neurodegenerative disorder and characterized by degeneration of dopamine (DA) neurons in substantia nigra pars compacta, leading to a loss DA basal ganglia. The presence aggregates alpha-synuclein (α-synuclein) seen as main contributor pathogenesis progression PD. Evidence suggests that secretome mesenchymal stromal cells (MSC) could be potential cell-free therapy for However, accelerate integration this clinical setting, there still need...
Current epidemiological data on heart failure (HF) in Portugal derives from studies conducted two decades ago. The main aim of this study is to determine HF prevalence the Portuguese population. Using current standards, manuscript aims describe methodology and research protocol applied.The Heart Failure Prevalence Observational Study (PORTHOS) a large, three-stage, population-based, nationwide, cross-sectional study. Community-dwelling citizens aged 50 years older will be randomly selected...