A5059875013- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Microbial infections and disease research
- Plasmonic and Surface Plasmon Research
- RNA modifications and cancer
- Terahertz technology and applications
- Blood groups and transfusion
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- RNA Research and Splicing
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
- Photonic and Optical Devices
- Streptococcal Infections and Treatments
- Force Microscopy Techniques and Applications
- Bacteriophages and microbial interactions
- Mechanical and Optical Resonators
- Nanoparticle-Based Drug Delivery
- Cancer, Hypoxia, and Metabolism
- Metamaterials and Metasurfaces Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer, Lipids, and Metabolism
- Tuberculosis Research and Epidemiology
- Viral-associated cancers and disorders
- Caveolin-1 and cellular processes
Central South University
2018-2025
Xiangya Hospital Central South University
2021-2025
Second Xiangya Hospital of Central South University
2020-2025
Xi'an Jiaotong University
2025
National Clinical Research
2025
Hunan Cancer Hospital
2018-2023
Tokyo Institute of Technology
2016-2023
Western Digital (United States)
2023
Nanyang Medical College
2023
Third Xiangya Hospital
2022
Abstract Epstein-Barr virus (EBV) is reportedly the first identified human tumor virus, and closely related to occurrence development of nasopharyngeal carcinoma (NPC), gastric (GC), several lymphomas. PD-L1 expression elevated in EBV-positive NPC GC tissues; however, specific mechanisms underlying EBV-dependent promotion induce immune escape warrant clarification. EBV encodes 44 mature miRNAs. In this study, we find that EBV-miR-BART11 EBV-miR-BART17-3p upregulate EBV-associated GC....
Abstract Background Circular RNAs (circRNAs) are widely expressed in human cells and closely associated with cancer development. However, they have rarely been investigated the context of nasopharyngeal carcinoma (NPC). Methods We screened a new circRNA, circRNF13 , NPC using next-generation sequencing mRNA. Reverse transcription polymerase chain reaction RNA fluorescence situ hybridization were used to detect expression 12 non-tumor epithelial (NPE) tissues 36 samples. Cell proliferation...
Abstract There is increasing evidence that long non-coding RNAs (lncRNAs) play important roles in human tumorigenesis. By using publicly available expression profiling data from lung adenocarcinoma and integrating bioinformatics analysis, we screened a lncRNA, LINC00472. LINC00472 tissues was significantly lower tightly associated with patient prognosis TNM clinical stages adenocarcinoma. also inhibited cell migration invasion increased stiffness adhesion. RNA pull down RIP assays identified...
Abstract Background Circular RNAs (circRNAs) act as gene expression regulators and are involved in cancer progression. However, their functions have not been sufficiently investigated nasopharyngeal carcinoma (NPC). Methods The profiles of circRNAs NPC cells within different metastatic potential were reanalyzed. Quantitative reverse transcription PCR situ hybridization used to detect the level circPVT1 tissue samples. association with clinical properties patients was evaluated. Then, effects...
Tumor microenvironment (TME) heterogeneity leads to a discrepancy in survival prognosis and clinical treatment response for patients with HCC. The applications of documented molecular subtypes are constrained by several issues.
Abstract Plasmon-based devices are powerful for use in highly sensitive evanescent-field detection and analysis, but they exhibit the problem of limited frequency tunability fixed structures. This feature causes problems multi-frequency investigations required materials characterization, bio-related research, etc. Here, we propose fabricate a spiral-shaped plasmonic structure that enables continuous frequency-tuneable concentration terahertz (THz) region with simple operation. The device...
Abstract Antisense circular RNA is a special type of that derived from the antisense complementary strand parental mRNA. However, function circRNA in hepatocellular carcinoma (HCC) still unclear. Here, we reported CSF3R-AS was upregulated HCC and correlated with poor prognosis. promoted proliferation, angiogenesis, metastasis HCC, inhibited apoptosis. Mechanistically, has 180-base pairing sequence its mRNA CSF3R, which can directly bind to CSF3R recruit RBMS3 stabilize mRNA, finally activate...
A total of 6626 patients with CRC who were initially referred for endoscopic polypectomy enrolled from the Surveillance Epidemiology and End Results Database. Results: Most (6557/6626, 99.0%) at T0-T1 stage (American Joint Committee on Cancer staging system). Propensity score matching (PSM) inverse probability treatment weighting (IPTW) used to reduce selection bias, which resulted in balanced groups without lymphadenectomy, no difference CSS (p = .99 .074, respectively). In subgroup...
Breast cancer is the most common malignant tumor in women, and its incidence increasing each year. To effectively treat breast cancer, it important to identify genes involved occurrence development exploit them as potential drug therapy targets. Here, we found that potassium channel subfamily K member 6 (KCNK6) significantly overexpressed however, function tumors has not been reported. We further verified KCNK6 expression upregulated biopsies. Moreover, was enhance proliferation, invasion,...
Although terahertz technology has demonstrated strong potential for various applications, detectors operating in the region are yet to be fully established. Numerous designs have been proposed sensitive detection, with a nanowire-based field-effect transistor (FET) being one of most promising candidates. In this study, we use Ge-core/a-Si-shell nanowire coupled bow-tie antenna fabricate FET structure detection. We achieved high responsivity and low noise equivalent power (NEP) upon...