A5090604281- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Advancements in Photolithography Techniques
- Electron and X-Ray Spectroscopy Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Glaucoma and retinal disorders
- Venous Thromboembolism Diagnosis and Management
- Ocular Diseases and Behçet’s Syndrome
- Intracranial Aneurysms: Treatment and Complications
- Neurological Disorders and Treatments
- Integrated Circuits and Semiconductor Failure Analysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Retinal Diseases and Treatments
- Peripheral Neuropathies and Disorders
- Myasthenia Gravis and Thymoma
- Systemic Lupus Erythematosus Research
- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- CNS Lymphoma Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Nanofabrication and Lithography Techniques
Hiroshima City Asa Citizens Hospital
2015-2025
Citizens Specialty Hospitals
2015-2024
Yokohama City University
2003-2023
Fuji Heavy Industries Health Insurance Society Ota Memorial Hospital
2017-2020
Nomura Research Institute
2013-2018
Memorial Hospital
2017
Kyoto University
2017
City Hospital
2016
Asahikawa Kosei Hospital
1998-2015
Hiroshima University
1996-2014
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder characterized by psychiatric symptoms, seizures, and dyskinesias. This case report describes a 30-year-old woman who was initially suspected of having somatic symptom because the development seizures mimicking psychogenic non-epileptic (PNES). At presentation, she able to engage in conversation follow instructions, but exhibited slight fever, sensory abnormalities, non-stereotypical seizures. Over course two...
Sarcoidosis is a heterogeneous and multisystem granulomatous disorder. The etiology still uncertain, but the disease currently thought to be triggered by various genetic as well environmental factors. Recently, an association between sarcoidosis butyrophilin-like 2 (BTNL2) gene located in close proximity HLA-DRB1 was reported. purpose of our study verify relationship BTNL2 HLA risk alleles for susceptibility sarcoidosis, assess whether independent alleles.In study, 11 single nucleotide...
Discharge planning for inpatients with acute stroke can enhance reasonable use of healthcare resources, as well improve clinical outcomes and decrease financial burden patients. Especially, prediction discharge destination is crucial planning. This study aimed to develop an assessment model identify patients a high possibility home after stroke.We reviewed the electronic medical records 3200 who were admitted center in Japan between January 1, 2011, December 31, 2015. The outcome variable...
Abstract: Behçet’s disease (BD) is known to be associated with human leukocyte antigen (HLA) B51 in many different ethnic groups. An increased incidence of HLA‐B51 the patient group has also been reported a Japanese population. Recently, identified comprise 21 alleles, B*5101–B*5121. Further, not only HLA‐B*5101 but HLA‐B*5108 were found relatively groups among Italian and Saudi Arabian populations. Therefore, we performed HLA‐B*51 allele genotyping by polymerase chain reaction‐sequencing...
<b>BACKGROUND AND PURPOSE:</b> Although accumulating evidence suggests the presence of microbleeds as a risk factor for intracerebral hemorrhage (ICH), little is known about its significance in anticoagulated patients. The aim this study was to determine whether associated with recurrent hemorrhagic stroke patients who had received warfarin following atrial fibrillation–associated cardioembolic infarction. <b>MATERIALS METHODS:</b> A total 87 consecutive acute stroke, including 15 ICH and 72...
Background: The diagonal ear-lobe crease (ELC) is reported to be a marker of cardiovascular disease. Very few reports have assessed the relationship ELC with atherosclerosis. This investigated here using Japanese population. Methods and Results: A prospective cross-sectional study included 212 consecutive patients. Bilateral ear lobes were checked for this was followed by carotid ultrasonography measure far wall common artery intima-media thickness (CCA-IMT), plaque score (PS) number (PN)....
Thirteen Saudi Arabian patients with Behçet’s disease (BD) were typed for HLA‐A and ‐B alleles by the conventional serologic typing HLA‐DRB1, ‐DQB1 ‐DPB1 polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) method. As a result, phenotype frequency of B51 antigen was significantly increased in patient group as compared to ethnically matched control (76.9% vs. 22.2% controls), but no significant difference observed HLA‐A, ‐DRB1, or between controls, previously Japanese...
Abstract The human leukocyte antigen (HLA) region has been implicated in the pathogenesis of inflammatory bowel disease (IBD), which is classified into Crohn’s (CD) and ulcerative colitis (UC). Recently, an association between sarcoidosis butyrophilin‐like 2 ( BTNL2 ) gene was reported. located HLA its messenger RNA expressed most abundantly intestine. In this study, we performed a case–control study Japanese patients with IBD linkage disequilibrium (LD) analysis HLA‐DRB1 . We analyzed eight...
Abstract: We have previously suggested that in a Japanese population the susceptible locus for Behçet's disease (BD) is HLA‐B51 itself. To confirm this finding another population, we performed HLA class I typing using PCR‐SSP method and analyzed eight polymorphic markers distributed within 1100 kb around HLA‐B gene automated sequencer subsequent fragment detection by fluorescent‐based technology with DNA samples of 84 Iranian patients BD 87 healthy ethnically matched controls. As result,...
To assess the efficacy of topical Semaphorin-3A (SEMA3A) in treatment allergic conjunctivitis.Experimental conjunctivitis (EAC) mice model induced by short ragweed pollen (SRW) 4-week-old BALB/c mice, were evaluated using haematoxylin and eosin (H&E) staining, immunofluorescence light microscope photographs. Early phase took samples 24h after instillation late between 4 to 14d start treatment. The study use SEMA3A (10 U, 100 1000 U) eye drops subconjunctival injection with same...
Nocturnal and circadian intraocular pressure (IOP) fluctuations are important issues in glaucoma treatment. Ripasudil 0.4% eye drops, a new medication, lowers IOP by increasing aqueous humor outflow through the trabecular meshwork. We aimed to compare differences between measured using contact lens sensor (CLS) before after administering ripasudil drops adjunctively patients with primary open-angle (POAG) normal tension (NTG). Patients POAG (n = 1) NTG 5) underwent 24 h monitoring CLS every...
Eyes with epiretinal membranes (ERMs) often have alterations of retinal vessels. The authors studied perifoveal microcirculation in eyes using scanning laser ophthalmoscope (SLO) fluorescein angiography.Mean capillary blood flow velocity (CFV) was measured as an index by SLO angiography 26 ERMs (19 idiopathic membranes, seven after detachment surgery) before and 6 months vitreous surgery, 23 healthy control subjects.The mean CFV significantly reduced compared controls (p=0.012), the...
Although MBs, ICH, and LI are secondary to cerebral microangiopathy, it remains unclear whether the location of subsequent ICH/LI corresponds previous MBs. We performed this study clarify positional relationship between recurrent previously detected MBs.We evaluated patients with who had as shown on prior T2*-weighted MR imaging. assessed retrospectively corresponded that MB. Patients ICH were divided into deep group lobar group, hematoma MBs was evaluated.A total 55 patients, including 34...
Purpose: To identify changes in visual acuity and intra-ocular pressure (IOP) 12 months after the development of bleb-related infection. Methods: Data obtained from 146 eyes patients with infection were analyzed as a part Japan Glaucoma Society Survey Bleb-related Infection. Multiple logistic regression analysis was conducted to factors associated poor prognosis increased IOP for being stage III. Results: The logMAR by mean 0.140, 0.440, 1.099 1.122 at postinfection I, II, IIIa IIIb...
Eyes with idiopathic epiretinal membranes (ERM) often have tortuous vessels and macular edema, suggesting that eyes ERM may a disturbance of the microcirculation. The authors studied perifoveal microcirculation in by means scanning laser ophthalmoscope (SLO) fluorescein angiography.Mean capillary blood flow velocity (CFV) was measured SLO angiography 19 before 6 months after vitreous surgery healthy control eyes.Mean CFV significantly reduced compared (2.98 +/- 0.32 mm/sec versus 3.34 0.12...