Srinivas Murki

ORCID: 0000-0003-1012-1925
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Congenital Diaphragmatic Hernia Studies
  • Infant Development and Preterm Care
  • Infant Nutrition and Health
  • Neuroscience of respiration and sleep
  • Neonatal Health and Biochemistry
  • Respiratory Support and Mechanisms
  • Neonatal and Maternal Infections
  • Airway Management and Intubation Techniques
  • Neonatal and fetal brain pathology
  • Metabolism and Genetic Disorders
  • Antibiotic Use and Resistance
  • Congenital Heart Disease Studies
  • Birth, Development, and Health
  • Pediatric Hepatobiliary Diseases and Treatments
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Ultrasound in Clinical Applications
  • Cardiovascular Conditions and Treatments
  • Sepsis Diagnosis and Treatment
  • Pneumonia and Respiratory Infections
  • Breastfeeding Practices and Influences
  • Intestinal Malrotation and Obstruction Disorders
  • Pregnancy and preeclampsia studies
  • Child and Adolescent Health
  • Global Maternal and Child Health

Rainbow Children's Hospital
2021-2024

Niloufer Hospital
2021-2024

Fernandez Hospital
2014-2023

Post Graduate Institute of Medical Education and Research
2001-2013

To gain an understanding of the variation in available resources and clinical practices between neonatal units (NNUs) low-income middle-income country (LMIC) setting to inform design observational study on burden unit-level antimicrobial resistance (AMR).A web-based survey using a REDCap database was circulated NNUs participating Neonatal AMR research network. The included questions about NNU funding structure, size, admission rates, access supportive therapies, empirical guidelines period...

10.1136/archdischild-2019-316816 article EN cc-by-nc Archives of Disease in Childhood 2019-08-24

<b><i>Background:</i></b> Nasal continuous positive airway pressure (nCPAP) is the standard noninvasive respiratory support for newborns with distress. Evidence high-flow nasal cannula (HFNC) as an alternative mode of inconclusive. <b><i>Objective:</i></b> The aim this work was to evaluate whether HFNC not inferior nCPAP in reducing need higher first 72 h life when applied a preterm neonates <b><i>Methods:</i></b>...

10.1159/000484400 article EN Neonatology 2018-01-01

Background With increasing use of nCPAP, the safety and comfort associated with nCPAP have come into forefront. The reported incidence nasal injuries is 20% to 60%. A recent meta-analysis concluded that masks significantly decreases CPAP failure moderate severe injury stress need for a well powered RCT confirm their findings. Methods In this Open label, 3 arms, sequential, stratified randomized controlled trial, we evaluated severity at removal when using two different interfaces in three...

10.1371/journal.pone.0211476 article EN cc-by PLoS ONE 2019-01-31

Abstract Aim: To study the effect of Kangaroo mother care in ward comparison with conventional at neonatal unit on growth and breastfeeding very low birth weight infants 40 weeks’ corrected gestational age. Methods: One hundred forty neonates <1500 g were randomized. The primary outcome was average gain (g/kg/day) from time randomization to term Results: Mean weight, age days similar both groups. At age, post (23.3 ± 8.7 vs. 22.64 9.1 g, p = 0.67) rate (85.9% 87.0%) comparable. There no...

10.1111/apa.12023 article EN Acta Paediatrica 2012-09-28

The prevalence of antimicrobial resistance in India is among the highest world. Antimicrobial use inpatient settings an important driver resistance, but poorly characterized, particularly hospitalized children. In this study, conducted as part Global Resistance, Prescribing, and Efficacy Neonates Children (GARPEC) project, we examined indications use, well agents used children by conducting four point surveys six hospitals between February 2016 2017. A total 681 were across all survey days,...

10.3390/antibiotics6030019 article EN cc-by Antibiotics 2017-09-13

Close monitoring of growth pattern in preterm neonates is essential to identify any deviations from the normal pattern. But, there no international consensus regarding how should be monitored or what constitutes ideal these premature infants.To compare incidence IUGR & EUGR ≤32 weeks gestational age based on Fenton 2013 curves and Intergrowth-21 standards.Retrospective Cohort Study.Tertiary care neonatal unit with nearly 1000 admissions unit.All newborns (230 6/7 days) admitted NICU within...

10.1080/14767058.2019.1670795 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2019-10-27

Securing long-term venous access is an essential part of sick newborn care. The malposition central line tip leads to several complications. There a need for easily available bedside investigating tool diagnose these malpositions. This study was done compare the effectiveness real-time ultrasound (RTUS) with X-ray in identifying peripherally inserted catheter (PICC) tip.This pilot observational conducted level III Neonatal Intensive Care Unit tertiary care hospital India, from June 2012...

10.4103/ijmr.ijmr_1542_14 article EN The Indian Journal of Medical Research 2017-03-01

Context Morbidity and mortality amongst extremely low birth weight (ELBW) gestational age neonates (ELGANs) in developing nations has not been well studied. Objectives Evaluate survival until discharge, short- long-term morbidities of ELBW ELGANs LMICs. Data sources CENTRAL, EMBASE, MEDLINE Web Science. Study selection Prospective retrospective observational studies were included. extraction synthesis Four authors extracted data independently. Random-effects meta-analysis proportions was...

10.1371/journal.pone.0255352 article EN PLoS ONE 2021-08-05

While there have been studies in adults reporting discordant empiric antibiotic treatment associated with poor outcomes, this area is relatively unexplored children and neonates despite evidence of increasing resistance to recommended first-line regimens.Patient characteristics, treatment, microbiology, 30-day all-cause outcome from <18 years blood-culture-confirmed bacterial bloodstream infections (BSI) were collected anonymously using REDCap™ through the Global Antibiotic Prescribing...

10.1097/inf.0000000000002910 article EN The Pediatric Infectious Disease Journal 2021-01-04

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Preterm neonates with respiratory distress syndrome (RDS) benefit from early application of nasal continuous positive airway pressure (nCPAP). However, it is not clear whether surfactant should be administered as a routine to all such infants or later in selective manner. &lt;b&gt;&lt;i&gt;Objective:&lt;/i&gt;&lt;/b&gt; It was the aim this study compare efficacy versus late treatment reducing need for mechanical ventilation (MV) during first...

10.1159/000345198 article EN Neonatology 2012-12-11

Internet-based distance learning combined with local hands-on skill enhancement can provide high-quality standardized education to in-service healthcare professionals in a wide geographical area.Primary objective of this study was evaluate the efficacy internet-based conjunction improving knowledge and skills essential newborn care among nursing health professionals.A total 98 participants from seven facilities India Maldives were enrolled study. Delivery course material staggered over 5...

10.1093/tropej/fms029 article EN Journal of Tropical Pediatrics 2012-07-12
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