A5101733962- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Cancer Treatment and Pharmacology
- Thyroid Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Geometric Analysis and Curvature Flows
- HER2/EGFR in Cancer Research
- Estrogen and related hormone effects
- Breast Implant and Reconstruction
- Neutropenia and Cancer Infections
- Cancer Risks and Factors
- Advanced Differential Geometry Research
- BRCA gene mutations in cancer
- Thyroid and Parathyroid Surgery
- Metastasis and carcinoma case studies
- Inflammatory mediators and NSAID effects
- Advanced X-ray Imaging Techniques
- Particle Accelerators and Free-Electron Lasers
- Geometry and complex manifolds
- Chemotherapy-related skin toxicity
- Cancer and Skin Lesions
- Head and Neck Anomalies
- Cancer, Lipids, and Metabolism
- Pituitary Gland Disorders and Treatments
- Colorectal Cancer Surgical Treatments
Sungkyunkwan University
2024-2025
Kyungpook National University
1997-2025
St. Vincent's Hospital
2015-2024
Samsung Medical Center
2024
Mount Sinai Hospital
2024
Icahn School of Medicine at Mount Sinai
2024
St. Vincent's Birmingham
2015-2023
Catholic University of Korea
2007-2023
Suwon Catholic University
2023
St Vincent's Hospital
2023
To evaluate the role of diffusion-weighted imaging (DWI) in detection breast cancers, and to correlate apparent diffusion coefficient (ADC) value with prognostic factors.Sixty-seven women invasive cancer underwent MRI. Histological specimens were analyzed for tumor size grade, expression estrogen receptors (ER), progesterone receptors, c-erbB-2, p53, Ki-67, epidermal growth factor receptors. The computed mean ADC values normal parenchyma compared. Relationships between factors determined...
Systemic inflammatory markers derived from peripheral blood cell, such as the neutrophil-lymphocyte ratio (NLR), (dNLR), platelet-lymphocyte (PLR) and lymphocyte-monocyte (LMR), have been demonstrated prognostic in several types of malignancy. Here, we investigated compared association between systemic survival developed a nomogram breast cancer patients. We reviewed clinical pathological records 661 patients diagnosed with invasive carcinoma 1993 2011. The NLR, dNLR, PLR LMR immediate...
The association between body mass index (BMI) at the time of breast cancer diagnosis and prognosis patients remains controversial. Furthermore, BMI with respect to different subtypes is not clearly defined. We analyzed data from 41,021 invasive January 1988 February 2008 Korean Breast Cancer Registry (KBCR) database. Overall survival (OS) cancer-specific (BCSS) were using Kaplan-Meier method Cox's proportional hazard regression model among all specific categories. A U-shaped mortality was...
The need for an initial learning experience in laparoscopic colorectal cancer surgery has been well established. However, the inherent differences complexity and results of rectal surgery, as compared to colon warrant a study analyze curve exclusively resections.four hundred thirty-one patients operated on between April 1994 March 2006 were analyzed retrospectively changes surgical outcomes according case sequence. A multidimensional analysis was done, based following parameters: conversion...
In this paper we give a new characterization of real hypersurfaces type B, that is, tube over totally geodesic <TEX>$\mathbb{Q}P^n$</TEX> in complex two-plane Grassmannians <TEX>$G_2(\mathbb{C}^{m+2})$</TEX>, where m = 2n, with the Reeb vector <TEX>$\xi$</TEX> belonging to distribution <TEX>$\mathfrak{D}$</TEX>, <TEX>$\mathfrak{D}$</TEX> denotes subdistribution tangent space <TEX>$T_xM$</TEX> such <TEX>$\mathfrak{D}{\bigoplus}\mathfrak{D}^{\bot}$</TEX> for any point <TEX>$x{\in}M$</TEX> and...
Purpose Breast cancer treatment has progressed significantly over the past 20 years. However, knowledge regarding male breast (MBC) is sparse because of its rarity. This study an investigation clinicopathologic features, treatments, and clinical outcomes MBC. Materials Methods Clinical records 59 MBC patients diagnosed during 1995-2014 from seven institutions in Korea were reviewed retrospectively. Results Over a 20-year period, accounted for 0.98% among total patients, increased every 5 The...
We estimated the likelihood of breast cancer patients having axillary lymph node metastases (ALNM) based on a variety clinical and pathologic factors.Three hundred sixty-one without distant who underwent conserving surgery dissection (ALND) (level I II) or modified radical mastectomy (MRM) were identified, we retrospectively reviewed their pathology records treatment charts.Positive nodes detected in 104 for an overall incidence 28.8%: 2 (5%) with T1a tumor, 5 (9.2%) T1b 24 (21.8%) T1c tumor...
To evaluate the analgesic efficacy of bilateral superficial cervical plexus block and combined deep for incision pain, headache posterior neck pain after thyroidectomy.Ninety patients were divided into a control group (group C, n = 30), S, 30) CO, 30). Before general anaesthesia, we performed (18 ml) (14 (4 with 0.25% bupivacaine. Anaesthesia was maintained propofol-remifentanil-N2O-O2.The average concentration remifentanil significantly reduced in S compared C CO (1.1 +/- 0.3, 1.8 0.4, 0.7...
The anticancer effects of ruxolitinib and calcitriol against breast cancer were reported previously. However, the effect combination treatment on various molecular subtypes remains unexplored. In this study, we used MCF-7, SKBR3, MDA-MB-468 cells to investigate cell proliferation, apoptosis, cycle, signaling markers, in vitro vivo. Our results revealed synergistic SKBR3 cells, but not MCF-7 vitro, via proliferation inhibition, apoptosis induction, cycle arrest, alteration protein expression,...
Utilizing the concept of Reeb Jacobi operator Codazzi type, we investigate Hopf real hypersurfaces in complex hyperbolic two-plane Grassmannian $G^{*}_2(\mathbb {C}^{m+2})$ which admit a constant function α along direction ξ. If is direction, then vector field $\xi =-JN$ either belongs to distribution ${\mathfrak D}$ or D}^{\bot }$. By virtue this fact, have proved new result about type according \in \mathfrak {D}^{\bot }$ {D}$, respectively.
In this paper, we have considered linear Weingarten hypersurfaces in a sphere and obtained some rigidity theorems. The purpose of paper is to give extension the results due Cheng-Yau [3] Li [7].
Prevalence and phenotype of BRCA mutation can vary by race. The purpose this study is to evaluate the prevalence BRCA1/2 mutations in non-familial breast cancer patients with high risks Korea. A subset 758 was selected for from KOHBRA nationwide multicenter prospective cohort study. Mutations genes were tested using fluorescent-conformation sensitive gel electrophoresis, denaturing performance liquid chromatography or direct sequencing. Mutation identified 65 (8.6%) among total [BRCA1...
The hedgehog (Hh) signaling pathway is known to play a critical role in various malignancies, but its clinicopathologic breast cancer yet be established.Tissue microarray blocks from 334 cases of were prepared. expression six Hh proteins including sonic (Shh), patched (Ptch), smoothened (Smo), and the glioma-associated oncogene (Gli)-1, Gli-2, Gli-3 analyzed immunohistochemically.The was significantly correlated with some prognostic factors correlation lymph node metastasis Shh (p=0.001)...
Human leukocyte antigen class I (HLA-I) molecules play important roles in regulating immune responses. Loss or reduction of HLA-I expression has been shown to be associated with prognosis several cancers. Regulatory T-cells (Tregs) also critical functions response regulation. Evaluation status by the EMR8-5 antibody and its clinical impact breast cancer have not well studied, relationship Tregs remains unclear.We evaluated Treg infiltration immunohistochemistry 465 surgically resected...
Abstract “BRCAX” refers breast cancers occurring in women with a family history predictive of being BRCA1 /2 mutation carrier, but BRCA1/2 genetic screening has failed to find causal mutations. In this study, we report the findings architecture BRCAX novel and redefined candidate loci their potential impacts on preventive strategy. We performed genome-wide association study involving 1,469 cases from Korean Hereditary Breast Cancer high-risk cancer (1,482 Asians 9,902 Europeans) Association...