Yuanzhe Zhao

ORCID: 0000-0003-1066-9253
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About
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Research Areas
  • Magnetic confinement fusion research
  • Particle accelerators and beam dynamics
  • Superconducting Materials and Applications
  • Plasma Diagnostics and Applications
  • Fusion materials and technologies
  • Ionosphere and magnetosphere dynamics
  • Particle Accelerators and Free-Electron Lasers
  • Laser-Plasma Interactions and Diagnostics
  • Spinal Cord Injury Research
  • Distributed and Parallel Computing Systems
  • Advanced Memory and Neural Computing
  • Embedded Systems and FPGA Design
  • Nerve injury and regeneration
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nuclear Physics and Applications
  • Ferroelectric and Negative Capacitance Devices
  • Hydraulic Fracturing and Reservoir Analysis
  • Analytical Chemistry and Sensors
  • Molecular Junctions and Nanostructures
  • Galectins and Cancer Biology
  • Drilling and Well Engineering
  • Semiconductor materials and devices
  • Mass Spectrometry Techniques and Applications
  • Power Systems and Technologies
  • Nuclear reactor physics and engineering

Second Hospital of Anhui Medical University
2024-2025

Anhui Medical University
2024-2025

University of Macau
2022-2025

Institute of Microelectronics
2024-2025

Institute of Plasma Physics
2015-2024

Chinese Academy of Sciences
2015-2024

Hefei Institutes of Physical Science
2021-2024

Shanghai Electric (China)
2024

Northeast Petroleum University
2023

Dalian University of Technology
2022

The EAST research program aims to demonstrate steady-state long-pulse advanced high-performance H-mode operations with ITER-like poloidal configuration and RF-dominated heating schemes. Since the 2014 IAEA FEC, has been upgraded all ITER-relevant auxiliary current drive systems, enabling investigation of plasma profile control by coupling/integration various combinations. Fully non-inductive (H 98,y2 > 1.1) was extended over 60 s for first time sole RF plus good power coupling impurity...

10.1088/1741-4326/aa7861 article EN Nuclear Fusion 2017-06-09

Recent Experimental Advanced Superconducting Tokamak (EAST) experiments have successfully demonstrated a long-pulse steady-state scenario with improved plasma performance through integrated operation since the last IAEA FEC in 2016. A discharge duration over 100 s using pure radio frequency (RF) power heating and current drive has been obtained required characteristics for future tokamak reactors such as good energy confinement quality (H98y2 ~ 1.1) electron internal transport barrier inside...

10.1088/1741-4326/ab1c7b article EN Nuclear Fusion 2019-04-25

Lactate-derived histone lactylation is involved in multiple pathological processes through transcriptional regulation. The role of lactate-derived the repair spinal cord injury (SCI) remains unclear. Here we report that overall lactate levels and are upregulated after SCI. Notably, H4K12la was significantly elevated microglia injured cord, whereas exogenous treatment further Functionally, promoted microglial proliferation, scar formation, axon regeneration, locomotor function recovery...

10.1186/s12974-024-03186-5 article EN cc-by-nc-nd Journal of Neuroinflammation 2024-08-03

Abstract Background Myelin-laden foamy macrophages accumulate extensively in the lesion epicenter, exhibiting characteristics of autophagolysosomal dysfunction, which leads to prolonged inflammatory responses after spinal cord injury (SCI). Trehalose, known for its neuroprotective properties as an autophagy inducer, has yet be fully explored potential mitigate macrophage formation and exert therapeutic effects context SCI. Results We observed that trehalose significantly enhances...

10.1186/s13578-025-01357-2 article EN cc-by Cell & Bioscience 2025-01-29

Recent studies have confirmed the critical role of neonatal microglia in wound healing and axonal regeneration following spinal cord injury (SCI). However, limited migration to center adult lesion may significantly impede their potential benefits. We established a model microglial centripetal prolonged retention C57BL/6J transgenic mice by injecting exogenous C-X3-C motif chemokine ligand 1 (CX3CL1) macrophage colony-stimulating factor (M-CSF) directly into site post-SCI. Wound...

10.1186/s12974-025-03411-9 article EN cc-by-nc-nd Journal of Neuroinflammation 2025-03-12

Efficient excited state intramolecular proton transfer (ESIPT) OLED emitters are critical for the development of cost-effective and color-stable WOLEDs due to their significant Stokes shift, which minimizes spectral overlap. In...

10.1039/d4tc05193a article EN Journal of Materials Chemistry C 2025-01-01

Early detection of platinum resistance for ovarian cancer treatment remains challenging. This study aims to develop a machine learning model incorporating genomic data such as Single-Nucleotide Polymorphisms (SNPs) Human Sulfatase 1 (SULF1) with CT radiomic based on pre-treatment images, predict (OC) treatment.A cohort 102 patients pathologically confirmed OC was retrospectively enrolled into this from January 2006 February 2018. All had platinum-based chemotherapy after maximal...

10.1016/j.biopha.2020.111013 article EN Biomedicine & Pharmacotherapy 2020-11-20

Using a 2 MW 2.45 GHz lower hybrid wave (LHW) system installed in experimental advanced superconducting tokamak, we have systematically carried out LHW-plasma coupling and current drive experiments both divertor (double null single null) limiter plasma configuration with (Ip) ∼ 250 kA central line averaged density (ne) 1.0–1.3 × 1019 m−3 recently. Results show that the reflection coefficient (RC) first is flat up to some distance between LHW grill, then increases distance. Studies indicate...

10.1063/1.3624778 article EN Physics of Plasmas 2011-08-01

Abstract Two important issues in achieving lower hybrid current drive (LHCD) high confinement plasma EAST are to improve wave (LHW)-plasma coupling and the at a density. Studies different configurations with directions of toroidal magnetic field ( B t ) show that density near antenna is affected by both radial electric induced without LHW E r_plasma scrape off layer (SOL), power r_LH grill. Investigations indicate r × SOL leads effect configuration on LHW-plasma accounts for asymmetric...

10.1088/0029-5515/55/9/093030 article EN Nuclear Fusion 2015-08-21

This paper presents a weak PUF-assisted strong PUF that combines the metrics between and PUFs. Unlike conventional PUFs rely on nonlinear combination of large number entropy cells for high modeling attacks resilience, presented utilizes unique key streams to bitwise encrypt raw responses from facilitate an inherent immunity thus fulfilling high-level security. A device-specific pseudo-random generator (P-RNG) configured by dedicated array generates stream (K). Since are inherently immune...

10.1109/tcsi.2022.3206214 article EN IEEE Transactions on Circuits and Systems I Regular Papers 2022-09-21

The experiments were carried out to study the coupling characteristics of I-port antenna in ion cyclotron range frequencies (ICRF) EAST. dependencies resistance on various parameters including position, central electron density, gas injection and phasing have been studied. results obtained show that experimental data are consistent with theoretical simulations. We find loading decreases sharply at L-H transition due change plasma density profiles scrape-off layer (SOL). effect low hybrid...

10.1088/1741-4326/aa69ca article EN Nuclear Fusion 2017-04-28

Three identical new WEST Ion Cyclotron Resonance Heating (ICRH) antennas have been designed, assembled then commissioned on plasma from 2013 to 2019.The ICRH system is both load-resilient and compatible with long-pulse operations.The three successfully operated together in 2019 2020.The load resilience capability has demonstrated the antenna feedback controls for phase matching developed.The breakdown detection systems validated protected antennas.The use of combination Lower Hybrid...

10.1088/1741-4326/ac1759 article EN Nuclear Fusion 2021-07-23

Achieving steady-state plasma operation at high temperatures is one of the important goals worldwide magnetic fusion research. High approximately 1–2 keV, and sustainment operations have been reported. Recently regime was greatly extended in Large Helical Device (LHD). A high-temperature created maintained for 54 min with 1.6 GJ 2005FY experimental programme. The three-dimensional heat-deposition profile LHD helical divertor modified, during long-pulse discharges it effectively dispersed...

10.1088/0029-5515/47/9/023 article EN Nuclear Fusion 2007-08-29

A long-pulse high confinement plasma regime known as H-mode is achieved in the Experimental Advanced Superconducting Tokamak (EAST) with a record duration over 30 s, sustained by Lower Hybrid wave Current Drive (LHCD) advanced lithium wall conditioning and divertor pumping. This characterized co-existence of small Magneto-Hydrodynamic (MHD) instability, i.e., Edge Localized Modes (ELMs) continuous quasi-coherent MHD mode at edge. We find that LHCD provides an intrinsic boundary control for...

10.1063/1.4872195 article EN Physics of Plasmas 2014-04-30

In the context of spinal cord injury (SCI), infiltrating macrophages assume prominence as primary inflammatory cells within lesion core, where fibrotic scar is predominantly orchestrated by platelet-derived growth factor receptor beta (PDGFRβ

10.1186/s13578-024-01310-9 article EN cc-by Cell & Bioscience 2024-10-15
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