Mengmeng Li

ORCID: 0000-0003-1117-8106
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Research Areas
  • Conducting polymers and applications
  • Organic Electronics and Photovoltaics
  • Advanced Sensor and Energy Harvesting Materials
  • Perovskite Materials and Applications
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Electrospun Nanofibers in Biomedical Applications
  • Molecular Junctions and Nanostructures
  • Surface Modification and Superhydrophobicity
  • Nanoplatforms for cancer theranostics
  • Semiconductor materials and devices
  • 2D Materials and Applications
  • Organic Light-Emitting Diodes Research
  • Nanoparticle-Based Drug Delivery
  • Advanced Memory and Neural Computing
  • Graphene and Nanomaterials Applications
  • Corrosion Behavior and Inhibition
  • Analytical Chemistry and Sensors
  • Electrochemical sensors and biosensors
  • Bone Tissue Engineering Materials
  • Graphene research and applications
  • Advancements in Battery Materials
  • Luminescence Properties of Advanced Materials
  • Advanced Photocatalysis Techniques
  • Supercapacitor Materials and Fabrication

Chinese Academy of Sciences
2014-2025

Institute of Microelectronics
2019-2025

Qingdao University
2009-2025

University of Chinese Academy of Sciences
2020-2025

Xiamen University of Technology
2025

Changchun University of Chinese Medicine
2024-2025

Affiliated Hospital of Qingdao University
2025

Sichuan University
2019-2025

Shanghai Institute of Materia Medica
2024-2025

Changji University
2025

This work reports on a passive double spiral microfluidic device allowing rapid and label-free tumor cell separation enrichment from diluted peripheral whole blood, by exploiting the size-dependent hydrodynamic forces. A numerical model is developed to simulate Dean flow inside curved geometry track particle/cell trajectories, which validated against experimental observations serves as theoretical foundation for optimizing operating conditions. Results separating cells (MCF-7 Hela) spiked...

10.1039/c2lc40679a article EN Lab on a Chip 2012-01-01

All-polymer solar cells (all-PSCs) composed of conjugated polymers as both donor and acceptor components in bulk heterojunction photoactive layers have attracted increasing attention. However, it is a big challenge to achieve optimal morphology polymer:polymer blends. In response, we report herein new strategy adjust the nanoscale organization for all-PSCs. Specifically, side chain engineering well-known naphthalene diimide (NDI)-based polymer N2200 modulated by introducing fraction linear...

10.1021/jacs.8b05038 article EN Journal of the American Chemical Society 2018-06-26

The increasing demands for more efficient and brighter thin-film light-emitting diodes (LEDs) in flat-panel display solid-state lighting applications have promoted research into three-dimensional (3D) perovskites. These materials exhibit high charge mobilities low quantum efficiency droop

10.1038/s41586-024-07460-7 article EN cc-by Nature 2024-05-29

Osteoarthritis (OA) is a common joint disease known for cartilage degeneration, leading to substantial burden on individuals and society due its high disability rate. However, current clinical treatments defects remain unsatisfactory the unclear mechanisms underlying regeneration. Tissue engineering hydrogels have emerged as an attractive approach in repair. Recent research studies indicated that stem cells can sense mechanical strength of hydrogels, thereby regulating their differentiation...

10.1039/d3mh01581e article EN Materials Horizons 2024-01-01

Abstract With the rapid development of advanced technologies in Internet Things era, higher requirements are needed for next‐generation electronic devices. Fortunately, organic thin film transistors (OTFTs) provide an effective solution skin and flexible wearable devices due to their intrinsic features mechanical flexibility, lightweight, simple fabrication process, good biocompatibility. So far considerable efforts have been devoted this research field. This article reviews recent advances...

10.1002/smm2.1261 article EN cc-by SmartMat 2024-01-02

Abstract Organic electrochemical transistors have emerged as a solution for artificial synapses that mimic the neural functions of brain structure, holding great potentials to break bottleneck von Neumann architectures. However, current rely primarily on electrical signals, and little attention has been paid vital role neurotransmitter-mediated synapses. Dopamine is key neurotransmitter associated with emotion regulation cognitive processes needs be monitored in real time advance development...

10.1088/1674-4926/24090013 article EN Journal of Semiconductors 2025-01-01

Temporal lobe epilepsy (TLE) is often characterized pathologically by severe neuronal loss in the hippocampus. Understanding mechanisms of neuron death key to preventing neurodegeneration associated with TLE. However, involvement epileptogenic process has yet be fully determined. Recent studies have shown that activation NLRP1 can generate a functional caspase-1-containing inflammasome vivo drive proinflammatory programmed cell termed ‘pyroptosis’, which role pathogenesis neurological...

10.1186/s12974-014-0233-0 article EN cc-by Journal of Neuroinflammation 2015-01-01

A new family of Si-based pentagonal monolayers is constructed on the basis okayamalite structure by means first principles calculations.

10.1039/c5ta05770a article EN Journal of Materials Chemistry A 2015-01-01

In this work, we propose a rapid and continuous rare tumor cell separation based on hydrodynamic effects in label-free manner. The competition between the inertial lift force Dean drag inside double spiral microchannel results size-based of large cells small blood cells. mechanism curved was investigated by numerical model. Experiments with binary mixture 5- 15-μm-diameter polystyrene particles using channel showed purity more than 95% at flow rate above 30 ml/h. High throughput (2.5 × 108...

10.1063/1.4774311 article EN Biomicrofluidics 2013-01-01

In this paper, we report a quick approach to self-assemble three-dimensional (3D) spongiform nanofiber stacks via electrospinning, which usually fabricates 2D non-woven fiber mats. Through controlling experimental conditions, cone-like polystyrene can be self-assembled on aluminum foil within 30 min. The are able reach height of more than 10 cm. Moreover, conversion between the 3D stack and thin film controlled. formation mechanism influence conditions have also been explored. may promising...

10.1039/c2nr11782g article EN Nanoscale 2012-01-01

A series of "double-cable" conjugated polymers were developed for application in efficient single-component polymer solar cells, which high quantum efficiencies could be achieved due to the optimized nanophase separation between donor and acceptor parts. The new double-cable contain electron-donating poly(benzodithiophene) (BDT) as linear backbone hole transport pendant electron-deficient perylene bisimide (PBI) units electron transport, connected via a dodecyl linker. Sulfur fluorine...

10.1021/jacs.7b10499 article EN Journal of the American Chemical Society 2017-12-04

Abstract Polymorphism of organic semiconducting materials exerts critical effects on their physical properties such as optical absorption, emission and electrical conductivity, provides an excellent platform for investigating structure–property relations. It is, however, challenging to efficiently tune the polymorphism conjugated polymers in aggregated, semi-crystalline phases due conformational freedom anisotropic nature. Here, two distinctly different polymorphs ( β 1 2 ) a low-bandgap...

10.1038/s41467-019-10519-z article EN cc-by Nature Communications 2019-06-28

NLRP3 inflammasome is proposed to regulate inflammation in several neurological diseases, but its role epilepsy remains largely unknown. This study aimed investigate the of neuroinflammation, spontaneous recurrent seizures (SRS) and hippocampal neuronal loss rat brain following amygdala kindling-induced status epilepticus (SE). We detected protein levels IL-1β components by Western blot hippocampus shams SE rats at different time points SE. To further examine whether activation contributes...

10.1186/s12974-014-0212-5 article EN cc-by Journal of Neuroinflammation 2014-12-01

Donor-acceptor polymers with an alternating array of donor and acceptor moieties have gained particular attention during recent years as active components organic electronics. By implementation suitable subunits within the conjugated backbone, these can be made either electron-deficient or -rich. Additionally, their band gap light absorption precisely tuned for improved light-harvesting in solar cells. On other hand, polymer design also modified to encode desired supramolecular self-assembly...

10.1039/c6cc04523e article EN cc-by Chemical Communications 2016-01-01

ConspectusDonor–acceptor (D–A) conjugated polymers are of great interest as organic semiconductors, because they offer a rational tailoring the electronic properties by modification donor and acceptor units. Nowadays, D–A exhibit field-effect mobilities on order 10–2–100 cm2 V–1 s–1, while several examples showed mobility over 10 s–1.The development cyclopentadithiophene–benzothiadiazole (CDT–BTZ) copolymers one decade ago represents an important step toward high-performance semiconductors...

10.1021/acs.accounts.8b00025 article EN Accounts of Chemical Research 2018-04-17

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTDiketopyrrolopyrrole-Based Conjugated Polymers with Perylene Bisimide Side Chains for Single-Component Organic Solar CellsWenbin Lai†±, Cheng Li†, Jianqi Zhang‡, Fan Yang†±, Fallon J. M. Colberts§, Bing Guo⊥, Qiang Mike Wang§, Mengmeng Li§, Andong Zhang†±, René A. Janssen§, Maojie Zhang⊥, and Weiwei Li*†View Author Information† Beijing National Laboratory Molecular Sciences, Key of Solids, Institute Chemistry, Chinese Academy 100190, People's...

10.1021/acs.chemmater.7b02534 article EN Chemistry of Materials 2017-08-12

Abstract Because of its thickness‐dependent direct bandgap and exceptional optoelectronic properties, indium(III) selenide (In 2 Se 3 ) has emerged as an important semiconductor for electronics optoelectronics. However, the scalable synthesis defect‐free In flakes remains a significant barrier practical applications. Here, facile electrochemical strategy is presented ultrafast delamination bulk layered crystals in nonaqueous media, resulting high‐yield (83%) production with large lateral...

10.1002/adma.201907244 article EN cc-by Advanced Materials 2020-01-15

It is still a great challenge to fabricate conjugated polymer monolayer field-effect transistors (PoM-FETs) due intricate crystallization and film formation of polymers. Here we demonstrate PoM-FETs based on single polymer. The resulting are highly reproducible exhibit charge carrier mobilities reaching 3 cm2 V-1 s-1. high performance attributed the strong interactions chains present already in solution leading pronounced edge-on packing well-defined microstructure monolayer. reproducibility...

10.1038/s41467-017-02805-5 article EN cc-by Nature Communications 2018-01-25

Tumor-associated fibroblasts (TAFs), which form a predominant stromal cellular component of the tumor microenvironment, hinder delivery nanomedicine to deep cells and lead poor prognosis tumors. However, depletion TAFs by therapeutic agents results in secretion damage response program (DRP) molecules weaken efficacy treatment. This paper reports multifunctional size-switchable nanoparticle (denoted DGL (dendrigraft poly-l-lysine) (DGL)/GEM@PP/GA) for TAF-targeted regulation penetration....

10.1021/acsami.9b13957 article EN ACS Applied Materials & Interfaces 2019-10-16
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