Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and relationship between diet presence other chronic diseases such as obesity. The objective this study was analyze interaction a high fat APOA2 (rs3813627 rs5082), APOA5 (rs662799 rs3135506) LEPR (rs8179183 rs1137101) polymorphisms its obesity dyslipidemia young subjects. included 200 subjects aged 18 25 years (100 normal-weight 100 obese subjects)....

The human adenovirus 36 (Ad-36) is causally and correlatively associated in animals humans, respectively, with increased adiposity altered metabolic profile. In previous studies, the relationship between Ad-36 seropositivity obesity was established adults children. We evaluated association of positive antibodies to profile Mexican Seventy-five children normal-weight 82 were studied this research. All had a clinic assessment which included weight, height, body circumferences, skinfold...

Introduction: Currently, it is considered that the body fat accumulation at central level associated with presence of hypertriglyceridemia, hypertension and diabetes. The mass index (BMI) has been used to identify obesity in general population, but can not detect distribution fat, so be other anthropometric measures assess adiposity determine their relationship metabolic disorders present people excess weight. Objective: To evaluate measurements such as waist-hip ratio (WHR), BMI waist...

Lipoprotein lipase (LPL) is a key enzyme in lipid metabolism and associated with obesity, dyslipidemias, hypertension (HTN) type 2 diabetes mellitus (T2DM). LPL gene polymorphisms can be related the development of cardiovascular risk factors. The present study was conducted to analyze relationship HindIII S447X factors Mexican families. population comprised ninety members 30 families, which an index case had were included study. We evaluated body composition by bioelectrical impedance....

Lipoprotein lipase (LPL) is a key enzyme in lipid metabolismand associatedwith obesity, dyslipidemias, hypertension (HTN) and type 2 diabetes mellitus (T2DM). LPL gene polymorphisms can be related with the development of cardiovascular risk factors. The present study was conducted to analyze relationship HindIII S447X factors Mexican families. population comprised ninety members 30 families, which an index case had were included study. We evaluated body composition by bioelectrical...

We aim to identify Th1 and Th2 cell clusters in young subjects, including their clinical metabolic characteristics the Th1/Th2 balance.A total of 100 participants were included. The frequencies cells peripheral blood determined by flow cytometry. Serum C-reactive protein was measured using a turbidimetric assay, insulin levels quantified with an enzyme-linked immunosorbent assay. Circulating cytokine analyzed multiplex system.A cluster analysis performed determine balance group people, 3...

Dyslipidemia is a common metabolic disorder that may result from abnormalities in the synthesis, processing and catabolism of lipoprotein particles. Disorders concentrations elevated concentration oxidized lipoproteins (oxLDL) are risk factors pathogenesis cardiovascular diseases (CVD). CD36 plays an important role lipid metabolism polymorphisms gene related to factors. The purpose this study was evaluate whether there association between genotypes haplotypes five with levels young...

Background The association between elevated blood pressure and childhood overweight obesity has been documented in several studies. However, the linkage of with body fat distribution children is not well established. We investigated relationship both central subcutaneous adiposity BP 95th percentile or higher Mexican children. Methods Results Our study, using a sample from State Guerrero, Mexico was comprised 252 children, 124 girls 128 boys, an age range 6 to 13 years. Resting measured...

We analyzed the relationship of −794<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:msub><mml:mrow><mml:mtext>CATT</mml:mtext></mml:mrow><mml:mrow><mml:mn>5</mml:mn><mml:mtext>–</mml:mtext><mml:mn>8</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>and −173 G&gt;C MIF polymorphisms with mRNA and soluble in young obese subjects. A total 250 subjects, 150 normal-weight 100 were recruited study. Genotyping...

Abstract Background Several association studies have shown that -844 G/A and HindIII C/G PAI-1 polymorphisms are related with increase of levels, obesity, insulin resistance, glucose intolerance, hypertension dyslipidemia, which components metabolic syndrome. The aim this study was to analyze the allele genotype frequencies these in gene its syndrome a sample Mexican mestizo children. Methods This included 100 children an age range between 6-11 years divided two groups: a) 48 diagnosed b) 52...

Objective Few studies have investigated the relationships between high-sensitivity C-reactive protein (hs-CRP) concentration and conventional cardiometabolic markers in young adults. The aim of this study was to characterize profile adults who are at high cardiovascular risk, according hs-CRP concentration. Methods A cross-sectional conducted 300 (18 30 years old) from southern Mexico (n = 150 normal-weight n obese). Their circulating lipid glucose concentrations were measured using...

Interleukin-6 (IL-6) is a cytokine involved in inflammatory process, as well glucose and lipid metabolism. Several studies of the biological relevance IL-6 gene polymorphisms have indicated relationship with cardiovascular disease. The aim this study was to assess whether -174 G/C -572 are associated risk factors Mexican families. Ninety members 30 families, which an index case (proband) had obesity, were included study. We evaluated body composition by bioelectrical impedance. Peripheral...

bjective: To assess whether the -675 4G/5G polymorphism in plasminogen activator inhibitor-1 gene is associated with obesity and insulin resistance Mexican children.Methods: A cross-sectional study was performed 174 children, 89 normal-weight 85 obesity, aged from 6 to 13 years.All children were state of Guerrero, recruited three primary schools city Chilpancingo, Mexico.Insulin levels determined by immunoenzymatic assay.The homeostasis model assessment used determine resistance.The PAI-1...

Interleukin-6 (IL-6) is a cytokine involved in inflammatory process, as well glucose and lipid metabolism. Several studies of the biological relevance IL-6 gene polymorphisms have indicated relationship with cardiovascular disease. The aim this study was to assess whether –174 G/C –572 are associated risk factors Mexican families. Ninety members 30 families, which an index case (proband) had obesity, were included study. We evaluated body composition by bioelectrical impedance. Peripheral...

We studied the association of age, gender, and distribution body fat with prehypertension in a sample Mexican adults. This study was performed 900 adults (275 men 625 women), median age 42 years. Resting blood pressure measured duplicate, hypertension were defined according to JNC 7 criteria. The prevalence our population 11.56% 26.5%, respectively. significantly higher than women. Prehypertension associated middle old (odds ratio [OR] = 2.6 2.4, respectively, P < .001), abdominal obesity...

Oxidized low-density lipoproteins (ox-LDLs) are involved in atherosclerotic plaque formation and progression have been linked to insulin resistance (IR). Myeloperoxidase is a potent oxidant of related atherogenic risk. High-density (HDLs) considered antioxidants due their association with paraoxonase 1 (PON1). However, HDL can also be oxidized (ox-HDL), its relationship IR has not described. This study evaluated the between circulating levels myeloperoxidase 1, diet, serum ox-LDL ox-HDL...

&lt;i&gt;Background/Aims:&lt;/i&gt; It has been proposed that preeclampsia is a metabolic syndrome of pregnancy. The polymorphisms &lt;i&gt;Pst&lt;/i&gt;I and &lt;i&gt;Mae&lt;/i&gt;III &lt;i&gt;INS&lt;/i&gt;, &lt;i&gt;Nsi&lt;/i&gt;I &lt;i&gt;INSR&lt;/i&gt; Ala513Pro Gly972Arg &lt;i&gt;IRS1&lt;/i&gt; have associated with syndrome; moreover, the products these genes are functionally contiguous during insulin signaling. aim this study was to assess whether preeclampsia....

The analysis of polymorphic markers within or closely linked to the cystic fibrosis transmembrane regulator (CFTR) gene is useful as a molecular tool for carrier detection known and unknown mutations. To establish association between mutations in CFTR western Mexican (CF) patients, distribution XV2c/KM19 haplotypes was analyzed by PCR restriction enzyme digestion 384 chromosomes from 74 CF their unaffected parents, normal subjects. haplotype revealed that B present 71.9% compared 0% non-CF...

Objective Monocyte chemoattractant protein 1 (MCP-1) has been suggested to be involved in the pathophysiology of insulin resistance (IR); therefore, variants MCP-1 gene may contribute development this disease. The aim study was analyze relationship -2518 A>G (rs1024611) polymorphism with Mexican children. Subjects and methods A cross-sectional performed 174 children, including 117 children without 57 IR, an age range 6-11 years. Levels for serum high-sensitivity C-reactive were determined....