A5035353672- Diabetes Management and Research
- Diabetes Treatment and Management
- Lung Cancer Treatments and Mutations
- Airway Management and Intubation Techniques
- Metabolism, Diabetes, and Cancer
- Sarcoidosis and Beryllium Toxicity Research
- HER2/EGFR in Cancer Research
- Tracheal and airway disorders
- Pancreatic function and diabetes
- Cancer Genomics and Diagnostics
- Respiratory Support and Mechanisms
- Colorectal Cancer Treatments and Studies
- Infectious Diseases and Tuberculosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Peroxisome Proliferator-Activated Receptors
- Bone health and treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Urological Disorders and Treatments
- Diagnosis and treatment of tuberculosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Burn Injury Management and Outcomes
- Vascular Tumors and Angiosarcomas
- Occupational exposure and asthma
Chonnam National University Hospital
2015-2021
Chonnam National University
2014-2020
Chonnam National University Hwasun Hospital
2015-2018
Catholic University of Korea
2012-2014
Seoul St. Mary's Hospital
2013-2014
For patients requiring prolonged mechanical ventilation (PMV), weaning is difficult and mortality very high. PMV has been defined recently, by consensus, as constituting ≥21 consecutive days of (MV) for ≥6 hours per day. This study aimed to evaluate the clinical factors predicting failure in undergoing medical intensive care unit (ICU).We retrospectively reviewed laboratory characteristics 127 who received MV more than 21 ICU at Chonnam National University Hospital South Korea between...
Several cases of acquired resistance in patients with activating epidermal growth factor receptor (EGFR) mutation have been reported. However, rare clinical exist a transformation to small cell lung cancer (SCLC) following treatment EGFR-tyrosine kinase inhibitors (TKIs). We report case non-small (NSCLC) L858R at the time diagnosis. After failure EGFR-TKI therapy, we performed additional histopathologic examinations. confirmed that patient had histological from NSCLC SCLC. chemotherapy...
Purpose Direct sequencing (DS) is the standard method for detection of epidermal growth factor receptor (EGFR) gene mutation in non-small cell lung cancer (NSCLC); however, low sensitivity a problem. The aim this study to demonstrate higher rate EGFR with peptide nucleic acid (PNA) clamping compared DS. Materials and Methods This single arm, prospective patients stage IIIB/IV or relapsed NSCLC. Using tumor DNA from 138 patients, both DS PNA exon 18, 19, 20, 21 were performed. Discrepant...
This study aimed to evaluate hypersensitivity reactions anti-tuberculosis (TB) drugs.We retrospectively compared the clinical manifestations and treatment outcomes of single multiple drug (DHRs).Twenty-eight patients were diagnosed with anti-TB DHRs using oral provocation tests. Of these 28 patients, 17 (60.7%) had a 11 (39.3%) DHRs. The median age was 57.5 years (interquartile range [IQR], 39.2-73.2). total 18 (64.3%) men. number drugs causing 2.0 (IQR 2.0-3.0). Rifampin most common that...
Background The sensitivity of interferon-gamma release assays (IGRAs) in the detection Mycobacterium tuberculosis infection could be affected by conditions immune dysregulation. For this reason, diabetes mellitus (DM) may increase frequency indeterminate results IGRAs. However, there have been inconsistent reports role DM on IGRA results. Methods We retrospectively reviewed all patients who underwent QuantiFERON-TB Gold In-Tube testing (QFT-GIT) at Chonnam National University Hospital....
OBJECTIVE -To describe the extent of intentional insulin omission in an outpatient population women with insulin-dependent diabetes mellitus (IDDM) and examine its relationship to disordered eating, attitudes toward diabetes, other psychosocial factors, long-term complications, glycemic control.RESEARCH DESIGN A N D METHODS-Before their routinely scheduled clinic appointments, female IDDM patients who were 13-60 years age completed a self-report survey (final n -341).The included...
Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular tumor of borderline malignancy that originates from endothelial cells. Chest computed tomography (CT) performed during routine cancer screening revealed multiple small pulmonary nodules in 50-year-old man who had previously undergone endoscopic submucosal dissection early gastric cancer. To rule out metastatic nodules, wedge resection the left upper lobe was and frozen biopsy reported benign fibrotic nodule. Using...
We aimed to quantify stress-induced hyperglycemia and differentiate the glucose response between normal animals those with diabetes. also examined pattern in fluctuation induced by stress according type of diabetes.To load psychological on animal models, we used a predator model exposing rats cat for 60 minutes measured level from beginning end test monitor fluctuation. 1 diabetes (T1D) ten Sprague-Dawley using streptozotocin five Otsuka Long-Evans Tokushima Fatty as obese 2 (OT2D) 10...
: Chlorine-containing bleach can cause acute respiratory distress syndrome (ARDS) and chemical burns. However, simultaneous occurrence of the two conditions caused by this agent is very rare. We describe case a 74-year-old female who presented with shortness breath hemoptysis following accidental exposure to chlorine-containing bleach. She had second- third-degree burns on both buttocks thighs, received mechanical ventilation because development ARDS. Mechanical was discontinued day 6...
Abstract Rationale: Influenza is an infection caused by the influenza virus, and its symptoms are mostly mild self-limiting. However, can cause severe or fatal complications in high-risk patients. Although tracheobronchitis one of common influenza, necrotizing very rare. Herein, we describe a case causing airway obstruction complicated pandemic 2009 H1N1 influenza. Patient concerns: A 60-year-old man presented with fever dyspnea. On arrival at emergency room (ER), patient received oxygen 4...
Since the introduction of endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) mediastinal lymph nodes, incidence histopathologically-confirmed sarcoidosis has increased.The electronic medical records Chonnam National University (CNU) Hospital and CNU Hwasun (CNUHH) were searched for confirmed cases diagnosed between 1996 2014. Cases selected using a combination clinical, radiological, pathological evidence. Of 115 with relevant disease codes, 16 excluded, as they...
The fractional exhaled nitric oxide (FENO) test is useful in asthma patients. However, a few studies on its usefulness chronic obstructive pulmonary disease (COPD) patients have been reported. We analyzed the FENO level distribution and clinical characteristics according to COPD patients.From December 2014 June 2019, who underwent function tests at Chonnam National University Hospital were retrospectively evaluated for FENO, comorbidities, history, blood eosinophil, test. high group was...
We report a case showing the long-term clinical benefit of continued use gefitinib in patient with asymptomatic progression lung adenocarcinoma harboring an exon 19 deletion epidermal growth factor receptor gene. Although follow-up studies showed smoldering metastatic lesions, treatment controlled pulmonary for more than six years.
The aims of this study are to investigate the glycemic efficacy and predictive parameters vildagliptin therapy in Korean subjects with type 2 diabetes.In retrospective study, we retrieved data for who were on twice-daily 50 mg at least 6 months, classified into five treatment groups. In three groups, added their existing medication regimen; other two replaced one medications vildagliptin. We then analyzed changes glucose clinical characteristics.Ultimately, 327 study. Vildagliptin...
Abstract Background: Epidermal growth factor receptor (EGFR) mutations are well known predictive marker of targeted therapy. We compared the sensitivity EGFR mutation detection techniques between matched achival lung cancer tissue and peripheral blood sample. Methods: collected paired samples from plasma paraffin-embedded tumor obtained before EGFR-tyrosine kinase inhibitor (EGFR-TKI). DNA extraction was performed using QIAamp MinElute virus spin kit analysis done by two methods. The current...