J. Mitchell

ORCID: 0000-0003-1304-0696
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Research Areas
  • Astrophysics and Cosmic Phenomena
  • Nuclear Physics and Applications
  • Nuclear reactor physics and engineering
  • Particle Accelerators and Free-Electron Lasers
  • Particle accelerators and beam dynamics
  • Neutrino Physics Research
  • Dark Matter and Cosmic Phenomena
  • Superconducting Materials and Applications
  • Agricultural Economics and Policy
  • Nuclear Materials and Properties
  • Particle physics theoretical and experimental studies
  • Atomic and Subatomic Physics Research
  • Nuclear physics research studies
  • Laser-Plasma Interactions and Diagnostics
  • Radiation Detection and Scintillator Technologies
  • Neuropeptides and Animal Physiology
  • Gamma-ray bursts and supernovae
  • Nuclear and radioactivity studies
  • Radiation Therapy and Dosimetry
  • Radio Astronomy Observations and Technology
  • Computational Physics and Python Applications
  • Economics of Agriculture and Food Markets
  • Quantum Chromodynamics and Particle Interactions
  • Inflammatory mediators and NSAID effects
  • Magnetic confinement fusion research

University of Alaska Anchorage
2024

Providence College
2024

The University of Texas at Arlington
2024

Lawrence Berkeley National Laboratory
2024

Clark Atlanta University
2024

Southern University and Agricultural and Mechanical College
2023-2024

Lancaster University
2017-2021

European Organization for Nuclear Research
2016-2021

Cockcroft Institute
2017-2021

British Library
2021

High energy particle accelerators have been crucial in providing a deeper understanding of fundamental particles and the forces that govern their interactions. In order to increase or reduce size accelerator, new acceleration schemes need be developed. Plasma wakefield acceleration, which electrons plasma are excited, leading strong electric fields, is one such promising novel technique. Pioneering experiments shown an intense laser pulse electron bunch traversing plasma, drives fields 10s...

10.1038/s41586-018-0485-4 article EN cc-by Nature 2018-08-21

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE PREPARATION OF ALIPHATIC AMIDESJames A. Mitchell and E. Emmet. ReidCite this: J. Am. Chem. Soc. 1931, 53, 5, 1879–1883Publication Date (Print):May 1, 1931Publication History Published online1 May 2002Published inissue 1 1931https://pubs.acs.org/doi/10.1021/ja01356a037https://doi.org/10.1021/ja01356a037research-articleACS PublicationsRequest reuse permissionsArticle Views1745Altmetric-Citations93LEARN ABOUT THESE METRICSArticle Views are the...

10.1021/ja01356a037 article EN Journal of the American Chemical Society 1931-05-01

Introduction: Graduate healthcare students experience significant stressors during professional training. Mindfulness-Based Stress Reduction (MBSR) is a behavioural intervention designed to teach self-regulatory skills for stress reduction and emotion management. This study examines the impact of MBSR training on from five graduate programs in quasi-experimental trial. Methods : A total 13 completed program were compared with 15 controls. Both groups answered validated questionnaires...

10.4103/1357-6283.112794 article EN Education for Health 2013-01-01

Among surgical trainees, burnout and distress are prevalent, but mindfulness has been shown to decrease the risk of depression, suicidal ideation, burnout, overwhelming stress. In other high-stress populations, formal training improve mental health, yet this approach not tried in surgery.To test feasibility acceptability modified Mindfulness-Based Stress Reduction (MBSR) during residency.A pilot randomized clinical trial MBSR vs an active control was conducted with 21 interns a residency...

10.1001/jamasurg.2018.2734 article EN JAMA Surgery 2018-08-30

The Advanced Proton Driven Plasma Wakefield Acceleration Experiment (AWAKE) aims at studying plasma wakefield generation and electron acceleration driven by proton bunches. It is a proof-of-principle R&D experiment CERN the world׳s first experiment. AWAKE will be installed in former CNGS facility uses 400 GeV/c beam bunches from SPS. experiments focus on self-modulation instability of long (rms ~12 cm) bunch plasma. These are planned for end 2016. Later, 2017/2018, low energy (~15 MeV)...

10.1016/j.nima.2016.02.026 article EN cc-by Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2016-02-22

A DNA region not associated with conventional immunoglobulin gene rearrangement is rearranged in many lymphoid tumors. This region, designated here as rearranging (LyR) DNA, was cloned from plasmacytoma J558 which it had recombined 5' to a constant (C) of the alpha heavy (H) chain gene, C alpha, within switch (S) S involved switching CH genes. Sequence determination established that LyR recombination unit. does originate H locus, and discordance between copy number certain lines suggests...

10.1073/pnas.79.22.6966 article EN Proceedings of the National Academy of Sciences 1982-11-01

We have previously identified peroxiredoxin-3 (PRDX-3) as a cell-surface protein that is androgen regulated in the LNCaP prostate cancer (PCa) cell line. PRDX-3 member of peroxiredoxin family are responsible for neutralising reactive oxygen species. expression was examined tissue from 32 patients using immunohistochemistry. Subcellular distribution determined confocal microscopy. antiandrogen-resistant lines by western blotting and quantitative RT–PCR. The pathways overexpression knockdown...

10.1038/bjc.2013.396 article EN cc-by-nc-sa British Journal of Cancer 2013-07-23

10.1016/j.nima.2015.12.050 article EN publisher-specific-oa Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2016-01-02

We give direct experimental evidence for the observation of full transverse self-modulation a long, relativistic proton bunch propagating through dense plasma. The exits plasma with periodic density modulation resulting from radial wakefield effects. show that is seeded by ionization front created using an intense laser pulse copropagating bunch. extends over length following seed point. By varying one order magnitude, we frequency scales expected dependence on density, i.e., it equal to...

10.1103/physrevlett.122.054802 article EN cc-by Physical Review Letters 2019-02-08

The seeded self-modulation of a relativistic, charged particle bunch in plasma is shown to grow both along the and plasma, resulting transverse wakefield amplitudes that far exceed initial seed values.

10.1103/physrevlett.122.054801 article EN cc-by Physical Review Letters 2019-02-08

AWAKE is a proton-driven plasma wakefield acceleration experiment. % We show that the experimental setup briefly described here ready for systematic study of seeded self-modulation 400\,GeV proton bunch in 10\,m-long rubidium with density adjustable from 1 to 10$\times10^{14}$\,cm$^{-3}$. short laser pulse used ionization vapor propagates all way along column, suggesting full vapor. occurs bunch, at time and follows affects bunch.

10.1088/1361-6587/aa941c article EN Plasma Physics and Controlled Fusion 2017-10-17

We have measured the spin structure functions g2p and g2d virtual photon asymmetries A2p A2d over kinematic range 0.02≤x≤0.8 1.0≤Q2≤30 (GeV/c)2 by scattering 38.8 GeV longitudinally polarized electrons from transversely NH3 6LiD targets. The absolute value of A2 is significantly smaller than R positivity limit range, while g2 consistent with twist-2 Wandzura-Wilczek calculation. obtain results for twist-3 reduced matrix elements d2p, d2d d2n. Burkhardt-Cottingham sum rule integral ∫g2(x)dx...

10.1016/s0370-2693(99)00590-0 article EN cc-by-nc-nd Physics Letters B 1999-07-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSILICA GEL AS A CATALYST IN THE PREPARATION OF NITRILESJames A. Mitchell and E. Emmet. ReidCite this: J. Am. Chem. Soc. 1931, 53, 1, 321–330Publication Date (Print):January 1931Publication History Published online1 May 2002Published inissue 1 January 1931https://pubs.acs.org/doi/10.1021/ja01352a048https://doi.org/10.1021/ja01352a048research-articleACS PublicationsRequest reuse permissionsArticle Views603Altmetric-Citations16LEARN ABOUT THESE...

10.1021/ja01352a048 article EN Journal of the American Chemical Society 1931-01-01

A modification of the Halász-Pupp neurosurgical knife was used in female rats to completely or partially isolate medial basal hypothalamus from adjacent central nervous. Changes body weight and length, plasma GH levels, metabolism were measured. Whereas complete anterior cuts resulted increased length weight, posterior had no effect. At 7 months following surgery, non-stress levels not elevated any group, including those exhibiting enhanced linear growth. Ether stress decreased mean...

10.1159/000122075 article EN Neuroendocrinology 1972-01-01

Abstract Purpose: Gastrointestinal cancers frequently exhibit mutational activation of the Ras/MAPK pathway, which is implicated in resistance to ionizing radiation (IR) and chemotherapy. Concurrent radiotherapy 5-fluorouracil (5-FU) based chemotherapy commonly used for treatment gastrointestinal malignancies. We previously reported radiosensitization with selumetinib, an inhibitor MEK1/2. The purpose current study was evaluate if selumetinib could enhance radiosensitivity induced by 5-FU....

10.1158/1078-0432.ccr-11-0358 article EN Clinical Cancer Research 2011-06-21

The duration of gestation and the time onset parturition were measured by means a specially constructed recording apparatus. Animals exposed to 1 3 photoperiod schedules from Day 0 pregnancy (sperm-positive vaginal smear) parturition. Light regimens 2 hr⁄day (short), 14 (control), or 22 (long) used in these experiments. short delivered only on Days 21 gestation, control animals 21, 23, whereas long during through 24 pregnancy. data indicate that, with prolonged daily illumination, an...

10.1210/endo-87-3-472 article EN Endocrinology 1970-09-01

In all age groups, the use of opioids to treat chronic pain conditions has increased, yet impact on opioid tolerance development not been comprehensively addressed. this study, we investigated age-related differences in morphine rats. Rats aged 3 wk, mo, 6 and 1 yr were used study. Morphine (8 mg/kg) was injected subcutaneously twice each day its analgesic effect assessed by change tail-flick latency using a thermal stimulus 5 min before 30 after dosing. Tolerance defined as 75% reduction...

10.1213/01.ane.0000152192.23851.40 article EN Anesthesia & Analgesia 2005-05-20

The effects of surgical isolation the medial basal hypothalamus (MBH) on growth were studied in adult female rats. Isolation MBH caused a gradual increase naso-anal (N-A) length. N-A length was significantly increased 92 days after surgery and augmented rate continued until autopsy at 139 days. accompanied by marked gain body weight conspicuous obesity. Non-stress stress levels plasma hormone (GH) determined radio-immunoassay 7–11 weeks surgery. Rats with had circulating non-stress GH that...

10.1159/000122230 article EN Neuroendocrinology 1973-01-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUltraviolet Absorption Spectra of Linseed Oil: Determination Bodied-in-Vacuo and Blown Oil in Mixtures with Raw OilJ Mitchell, Jr H KraybillCite this: Ind. Eng. Chem. Anal. Ed. 1941, 13, 11, 765–768Publication Date (Print):November 1, 1941Publication History Published online1 May 2002Published inissue 1 November 1941https://pubs.acs.org/doi/10.1021/i560099a004https://doi.org/10.1021/i560099a004research-articleACS PublicationsRequest reuse...

10.1021/i560099a004 article EN Industrial & Engineering Chemistry Analytical Edition 1941-11-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE DECOMPOSITION OF KETONES IN THE PRESENCE SILICA GELJames A. Mitchell and E. Emmet. ReidCite this: J. Am. Chem. Soc. 1931, 53, 1, 330–337Publication Date (Print):January 1931Publication History Published online1 May 2002Published inissue 1 January 1931https://doi.org/10.1021/ja01352a049RIGHTS & PERMISSIONSArticle Views97Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since...

10.1021/ja01352a049 article EN Journal of the American Chemical Society 1931-01-01

The AWAKE collaboration prepares a proton driven plasma wakefield acceleration experiment using the SPS beam at CERN. A long bunch extracted from interacts with high power laser and 10 m rubidium vapor cell to create strong wakefields allowing sustained electron acceleration. probe these is created by an accelerator consisting of rf-gun booster structure. This source should provide beams intensities between 0.1 1 nC, lengths 0.3 3 ps emittance order 2 mm mrad. structure accelerate electrons...

10.1016/j.nima.2018.02.044 article EN cc-by-nc-nd Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment 2018-02-14

The 252Cf prompt-fission-neutron spectrum has been measured by time-of-flight techniques over the energy range 0.5 to 13 MeV. Significant analytical and experimental improvements earlier measurements were employed. data simultaneously analyzed with angular pattern of Bowman et al., using a model which includes anisotropy emission in neutron fragment coordinate system stationary source. Based on this analysis, mean is found be 2.105 ± 0.014 It also concluded that spectra are highly...

10.13182/nse73-a28979 article EN Nuclear Science and Engineering 1973-03-01
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