A5057460474- Body Image and Dysmorphia Studies
- Dermatology and Skin Diseases
- melanin and skin pigmentation
- Obsessive-Compulsive Spectrum Disorders
- Medicine and Dermatology Studies History
- Autoimmune Bullous Skin Diseases
- Contact Dermatitis and Allergies
- Skin Protection and Aging
- Complementary and Alternative Medicine Studies
- Genetic and rare skin diseases.
- Empathy and Medical Education
- Drug-Induced Adverse Reactions
- Autoimmune and Inflammatory Disorders
- Olfactory and Sensory Function Studies
- Asthma and respiratory diseases
- Sexual function and dysfunction studies
- Urticaria and Related Conditions
- Allergic Rhinitis and Sensitization
- Cancer and Skin Lesions
- Psoriasis: Treatment and Pathogenesis
- Sexuality, Behavior, and Technology
- Innovations in Medical Education
- Acne and Rosacea Treatments and Effects
- Cutaneous lymphoproliferative disorders research
- Biochemical Analysis and Sensing Techniques
Solihull Hospital
2011-2024
University Hospitals Birmingham NHS Foundation Trust
2018-2024
National Health Service
2018-2021
Heart of England NHS Foundation Trust
2011-2018
University of Nottingham
2007-2014
West Midlands Deanery
2010
Oxford University Hospitals NHS Trust
2010
University Hospital Coventry
2010
University College London
2008-2009
Warwick Hospital
2009
Male erectile dysfunction (ED) is common, frequently caused by pelvic arterial atherosclerosis, and a predictor of future cardiovascular disease. There an emerging association between psoriasis, the metabolic syndrome atherosclerotic We hypothesized that ED occurs more commonly in patients with at least part due to incipient which may offer opportunity for early intervention.To determine prevalence of, risk factors for, psoriasis comparison heterogeneous dermatology outpatient control...
Evidence for the effectiveness of vitiligo treatments is limited. To determine (i) handheld narrowband UVB (NB‐UVB) and (ii) a combination potent topical corticosteroid (TCS) NB‐UVB, compared with TCS alone, localized vitiligo. A pragmatic, three‐arm, placebo‐controlled randomized controlled trial (9‐month treatment, 12‐month follow‐up). Adults children, recruited from secondary care community, aged ≥ 5 years active affecting < 10% skin, were 1 : to receive (mometasone furoate 0·1% ointment...
Background Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy for vitiligo. Objective To explore the clinical effectiveness and cost-effectiveness of corticosteroid compared (1) hand-held (2) light/topical combination treatment localised Design Pragmatic, three-arm, randomised controlled trial 9 months a 12-month follow-up. Setting Sixteen UK hospitals – participants were recruited...
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for management delusional infestation (DI) in adults. Linked Comment: I. Coulson. Br J Dermatol 2022; 187:457.
The most common neuropathological substrates of dementia are Alzheimer’s disease, cerebrovascular and with Lewy bodies. A preliminary, retrospective postmortem analysis was performed the relative burden each pathology in 25 patients predominantly disease-type dementia. Log linear modelling used to assess relations between ApoE genotype, disease scores. Sixteen 18 cases (89%) a Braak neuritic score ⩽4 had, addition, significant or bodies, both. There inverse relation stage (p=0.015)....
Summary Bullous pemphigoid (BP) is one of the most common acquired immunobullous diseases. Rarely, development BP attributed to drug exposure. We present two cases BP, triggered by intravenous iodine, and associated with etanercept treatment in a patient psoriasis; first time, our knowledge, that either these associations has been reported. The recognition occasional drug-induced such as ours, timely cessation offending agent, may produce rapid clinical improvement decreased exposure potent...
BackgroundFew studies have explored the immunology and genetic risk of paradoxical eczema occurring as an adverse event biologic therapy in patients with psoriasis.ObjectivesWe sought to describe systemic inflammatory signature using proteomics explore whether this is genetically mediated.MethodsThis study used Olink Target 96 Inflammation panel on 256 serum samples from 71 psoriasis eczema, 75 controls identify differentially expressed proteins enriched gene sets. Case 1 or more time points...
Dermatological surgery is carried out by a variety of practitioners in primary and secondary care.To explore the activity histopathological outcomes among different groups dermatological surgeons dealing with skin cancers.Reports for all new tumour specimens processed our histopathology department over continuous 3-month period were reviewed retrospectively.One thousand, one hundred eleven identified. General (GPs) least accurate clinical diagnosis, 42.8% (59/138) their request forms...
Tuberculosis is a major infectious disease and functional studies have provided evidence that both the chemokine MIP-1α its receptor CCR5 play role in susceptibility to TB. Thus by measuring copy number variation of CCL3L1, one genes encode MIP-1α, genotyping promoter polymorphism -2459A > G (rs1799987) we investigate influence CCR5, independently combined, clinically active TB three populations, Peruvian population (n = 1132), !Xhosa 605) South African Coloured 221). The populations include...
The identification of robust endotypes-disease subgroups clinical relevance-is fundamental to stratified medicine. We hypothesized that HLA-C∗06:02 status, the major genetic determinant psoriasis, defines a psoriasis endotype relevance. Using two United Kingdom-based cross-sectional datasets-an observational severe-psoriasis study (Biomarkers Systemic Treatment Outcomes in Psoriasis; n = 3,767) and large population-based bioresource (UK Biobank, including 5,519 individuals with psoriasis)-we...
Journal Article Eruptive disseminated superficial porokeratosis with rapid resolution: a drug‐induced phenomenon? Get access J. M. R. Goulding, Goulding Departments of Dermatology Dr Jon Department Dermatology, Warwick Hospital, Lakin Road, Warwick, CV34 5BW, UK. E‐mail: jmrgoulding@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar K. Teoh, Teoh A. Carr, Carr Pathology, UK F. Humphreys, Humphreys B. C. Gee Clinical and Experimental Volume 34, Issue 8, 1...
Management of patients with current or previous depression who require isotretinoin treatment for acne is a challenging area. Current opinion favours the view that isotretinoin‐induced mood disturbance rare, idiosyncratic reaction, not reliably related to presence pre‐existing depression. Nonetheless, in absence definitive high‐quality study, there remains degree legitimate uncertainty. With input from psychiatrist, we created and administered detailed survey featuring range low‐, medium‐...
Dermatology specialty trainees (STs) in the United Kingdom (UK) are few number and will join a thinly spread national consultant body. It is of paramount importance to deliver training programmes highest quality for these doctors, central which establishment maintenance an educational climate conducive learning.To conduct pilot study evaluate dermatology STs one UK deanery (West Midlands).Secondary analysis published data was performed, from UK's General Medical Council (GMC) survey, Job...
Background Economic evidence for vitiligo treatments is absent. Objectives To determine the cost-effectiveness of (i) handheld narrowband ultraviolet B (NB-UVB) and (ii) a combination topical corticosteroid (TCS) NB-UVB compared with TCS alone localized vitiligo. Methods Cost-effectiveness analysis alongside pragmatic, three-arm, placebo-controlled randomized controlled trial 9 months' treatment. In total 517 adults children (aged ≥ 5 years) active affecting < 10% skin were recruited from...
Delusional infestation (DI) describes an unwavering fixed belief of with pathogens, despite a lack medical evidence supporting this. Effective management DI antipsychotics is made challenging by the that condition or infection rather than mental illness. A case series individuals diagnosed included 11% who were healthcare professionals (HCPs). We sought to characterise cohort HCPs presented in UK. The notes at specialist clinics between 2015 and 2019 reviewed. Demographic clinical data...
Dysaesthetic penoscrotodynia (DPSD) is a poorly understood disorder, in which men experience distressing symptoms such as burning pain their genital skin. Drugs for neuropathic are often used, but with little success. To review series of patients DPSD to highlight common themes and response treatment. Ten consecutive were identified from specialist male dermatology psychodermatology clinics at two centres. Clinical details, including psychiatric history, reviewed retrospectively. Patients no...