A5100428328- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Plant biochemistry and biosynthesis
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Photosynthetic Processes and Mechanisms
- Light effects on plants
- Salmonella and Campylobacter epidemiology
- Plant Genetic and Mutation Studies
- Plant and animal studies
- Postharvest Quality and Shelf Life Management
- Plant Stress Responses and Tolerance
- Epigenetics and DNA Methylation
- Flavonoids in Medical Research
- Polysaccharides and Plant Cell Walls
- Myasthenia Gravis and Thymoma
- Aquaculture Nutrition and Growth
- Polyamine Metabolism and Applications
- Natural product bioactivities and synthesis
- Viral gastroenteritis research and epidemiology
- Insect-Plant Interactions and Control
- Microencapsulation and Drying Processes
- Acute Myeloid Leukemia Research
- Tracheal and airway disorders
- Aquaculture disease management and microbiota
West China Hospital of Sichuan University
2025
Sichuan University
2025
Hainan University
2023-2025
Jilin Agricultural University
2025
Norwich Research Park
2017-2024
John Innes Centre
2015-2024
Institute of Pomology
2024
Chinese Academy of Sciences
2016-2024
Daping Hospital
2024
Army Medical University
2024
Plants respond to environmental stresses by altering gene expression, and several genes have been found mediate stress-induced but many additional factors are yet be identified. OsNAP is a member of the NAC transcription factor family; it localized in nucleus, shows transcriptional activator activity yeast. Analysis transcript levels rice showed that this was significantly induced ABA abiotic stresses, including high salinity, drought low temperature. Rice plants overexpressing did not show...
Abstract A large-scale metabolic quantitative trait loci (mQTL) analysis was performed on the well-characterized Solanum pennellii introgression lines to investigate genomic regions associated with secondary metabolism in tomato fruit pericarp. In total, 679 mQTLs were detected across 76 lines. Heritability analyses revealed that of less affected by environment than primary metabolism. Network allowed us assess interconnectivity and as well compare contrast their respective associations...
Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little plants are very poor sources. We have engineered the accumulation provitamin D3 in tomato by genome editing, modifying duplicated section phytosterol biosynthesis Solanaceous plants, to provide biofortified food with added possibility supplement production from waste material.
A serological mass survey was carried out in Wuzhou City 1980, 1,136 IgA/VCA-positive persons being followed up for 4 years. Altogether 35 NPC cases were detected, of which 15 (43%) stage I and 17 (48.5%) II, early (I + II) thus amounting to 91.5%. The detection rate 2.9 times higher than our outpatient clinic. IgA/VCA antibody could be detected 16-41 months prior clinical diagnosis NPC. We conclude that, if individuals are examined routinely once a year, can the stages evolution. annual...
Abstract Two-component signaling systems, involving His kinases, His-containing phosphotransfer proteins, and response regulators, have been implicated in plant responses to hormones environmental factors. Genomic analysis of Arabidopsis supports the existence 22 regulators (ARRs) that can be divided into at least two distinct groups designated type-A type-B. Phylogenetic indicates type-B family is composed one major minor subfamilies. The expression ARRs was examined by using both reverse...
Baicalein, wogonin, and their glycosides are major bioactive compounds found in the medicinal plant Scutellaria baicalensis Georgi. These flavones can induce apoptosis a variety of cancer cell lines but have no effect on normal cells. Furthermore, they many additional benefits for human health, such as anti-oxidant, antiviral, liver-protective properties. Here, we report isolation characterization two CYP450 enzymes, SbCYP82D1.1 SbCYP82D2, which function flavone 6-hydroxylase (F6H)...
Octoploid strawberry (Fragaria × ananassa Duch.) is a model plant for research and one of the most important non-climacteric fruit crops throughout world. The associations between regulatory networks metabolite composition were explored critical agricultural properties in octoploid strawberry, colour. Differences levels flavonoids are due to differences expression structural genes involved flavonoid biosynthesis. molecular mechanisms underlying colour compared red white varieties. FaMYB had...
Sweet cherries are economically important fruit trees, and their quality changes during development need to be determined. The mechanism of in sweet were determined by analyzing cherry fruits at 12 developmental stages. results showed that the soluble sugar, anthocyanin content, hormones all changed drastically color transition. Therefore, beginning conversion, end ripening state selected for comprehensive analysis metabolome transcriptome. Different sugars, such as D-glucose, sucrose,...
Low temperature is one of the environmental factors that restrict growth and geographical distribution peach ( Prunus persica L. Batsch). To explore molecular mechanisms brunches in response to cold, we analyzed metabolomics transcriptomics ‘Donghe No.1’ (cold-tolerant, CT) ‘21 st Century’ (cold-sensitive, CS) treated by different temperatures (-5 -30°C) for 12 h. Some cold-responsive metabolites (e.g., saccharides, phenolic acids flavones) were identified with upregulation only CT. Further,...
The tropane alkaloids (TAs) cocaine and hyoscyamine have been used medicinally for thousands of years. To understand the evolutionary origins trajectories serial biosynthetic enzymes TAs especially characteristic skeletons, we generated chromosome-level genome assemblies cocaine-producing Erythroxylum novogranatense (Erythroxylaceae, rosids clade) hyoscyamine-producing Anisodus acutangulus (Solanaceae, asterids clade). Comparative genomic phylogenetic analysis suggested that lack spermidine...
Abstract Plants and their associated microbes live in complicated, changeable, unpredictable environments. They usually interact with each other many ways through multidimensional, multiscale, multilevel coupling manners, leading to challenges the coexistence of randomness determinism or continuity discreteness. Gaining a deeper understanding these diverse interaction mechanisms can facilitate development data-mining theories methods for complex systems, coupled modeling systems different...
Progressive hemifacial atrophy (Parry-Romberg disease) is rare and involves all skin layers subcutaneous soft hard tissue. Autologous fat grafting has revolutionized the field of soft-tissue reconstruction augmentation, but long-term maintenance unpredictable. Stromal vascular fraction (SVF)-supplemented cell therapy offers new hope for improving graft survival, with good results, efficacy outcome in clinic are rarely studied using objective data.To compare viability SVF-supplemented grafts...
Leukemia stem cells (LSCs) are responsible for treatment failure and relapse in acute myeloid leukemia (AML). Therefore, development of novel LSCs-targeting therapeutic strategies is crucial clinical importance to improve the outcomes AML. Histone deacetylase (HDAC) inhibitors have shown potent specific anticancer cell activities preclinical studies. Chidamide, a benzamide-type selectively HDAC inhibitor, has been reported induce G1 arrest apoptosis relatively mature progenitor population,...
Trichomes are epidermal protuberances on aerial parts of plants known to play an important role in biotic and abiotic stresses. To date, our knowledge the regulation trichome formation crop species is very limited. Through phenotyping Solanum pennellii×S. lycopersicum (cv. M82) introgression population, we identified SlbHLH95 transcription factor as a negative regulator tomato. In line with this role, displayed low expression stems where trichomes present at high density. Overexpression...
Many Dendrobium species, which hold a high status and value in traditional Chinese medicine, grow on barks rocks the wild, often encountering harsh environments facing droughts. However, molecular mechanisms underlying shift photosynthetic pathway induced by drought remain unclear. To address this issue, three species with different pathways were selected for sequencing transcriptome data analysis after treatment. The findings included 134.43 GB of data, numerous Differentially Expressed...
Blueberries are highly prone to postharvest decay, resulting in significant nutrient loss and economic damage. Current research on the storage of blueberries primarily focuses techniques, while underlying mechanisms remain insufficiently explored. To further explore role exogenous melatonin (MT) delaying senescence blueberry fruit, this study treated fruits with sterile water (control) 300 μmol·L−1 MT during pink fruit stage. After maturation, were stored at 4 °C for 30 days, we investigated...
The approach for traditional uniportal video-assisted thoracoscopic surgery (Uni-VATS) is typically located on the lateral chest wall, resulting pain and visible scars may have a negative psychological impact patients. We present our preliminary experience with subcutaneous tunneled periareolar (STPA) in lung resection performed through Uni-VATS treating pulmonary nodules. From December 2023 to June 2024, five patients underwent this procedure, including three cases of wedge resection, one...
Abstract Spinosad is a widely used insecticide effective in controlling Aedes aegypti populations, but the molecular mechanisms underlying resistance remain poorly understood. This study explores role of serine protease, AeaSP (AAEL002624), potential detoxification ability spinosad. Our results showed crude protein Ae. degraded approximately 48% spinosad vitro within 1 h; based on our previous research, was believed to be potentially involved degradation Subsequently, recombinantly expressed...