A5032124580- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Risk Factors
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Cardiac Health and Mental Health
- Neurological Disease Mechanisms and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Lipid metabolism and disorders
- Cardiovascular Syncope and Autonomic Disorders
- Health Promotion and Cardiovascular Prevention
- Nutritional Studies and Diet
- Acute Myocardial Infarction Research
- Pregnancy and preeclampsia studies
- Obesity, Physical Activity, Diet
- Heart Rate Variability and Autonomic Control
- Inflammatory Biomarkers in Disease Prognosis
- Viral Infections and Immunology Research
- Diet and metabolism studies
- Cardiomyopathy and Myosin Studies
First Affiliated Hospital Zhejiang University
2022-2024
China Medical University
2019-2023
First Hospital of China Medical University
2019-2023
Abstract Background To investigate the relationship between triglyceride glucose-body mass index (TyG-BMI) and ischemic stroke. Methods Leveraging two Chinese general population surveys, Northeast China Rural Cardiovascular Health Study (NCRCHS, N = 11,097) National Stroke Screening Intervention Program in Liaoning (NSSIPL, 10,862), we evaluated TyG-BMI stroke by a restricted cubic spline multivariate logistic regression after adjusting age, sex, level of education, exercise regularly,...
Background Stroke has become a major burden and public health problem in rural China. We aimed to comprehensively assess the current status of stroke as well associated risk factors northeast Methods This population-based, cross-sectional study was conducted 10,926 adults (response rate 85.3%) aged ≥40 years residing A multistage cluster sampling method used select representative sample. The prevalent cases were considered survivors on 31 August 2017. diagnosed according World Health...
Abstract Background Hyperlipidemia (HLP) and hypertension (HTN) are both independent risk factors for ischemic stroke. This study aimed to assess whether HTN HLP have a synergistic effect on the of Methods Between January August 2013, 11,695 subjects in rural areas northeastern China were enrolled. The additive multiplicative scales used evaluate interaction. Results prevalence stroke was 5.7%. Using healthy group (without or HLP) as reference group, with had higher (odds ratio [OR]: 3.369,...
To investigate the epidemiological features of obesity in rural Northeast China.This was a 2017-2018 cross-sectional study 10,891 participants aged ≥40 years that designed to prevalence areas Liaoning Province. Demographic data, biochemical parameters, and physical examinations were completed by well-trained personnel. Logistic regression analyses then carried out independent risk factors associated cardiometabolic comorbidities obesity.The proportions general only, central combined 1.0%,...
Objective To evaluate the epidemiology of atrial fibrillation (AF) in northeast China. Methods This cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted Liaoning Province between September 2017 March 2019. A total 18 796 participants (28.9% urban, 71.1% rural) aged ≥40 years were included. All completed questionnaire underwent physical examination ECG. AF diagnosed according to history ECG findings. Results The overall prevalence 1.1%; it...
To investigate the status of hypertension and related risk factor disparities between urban rural areas northeast China.A multi-stage, stratified, cluster random sampling method was used to conduct cross-sectional survey in Liaoning Province 2017-2019. Finally, included 18,796 participants (28.9% urban, 71.1% rural) aged ≥40 years. The prevalence control rate were estimated based on Chinese guidelines 2017 American College Cardiology/American Heart Association (ACC/AHA) guidelines.The mean...
To investigate the relationship between atherogenic index of plasma (AIP) and ischemic stroke.We collected a range data from 11,495 residents (aged ≥35 years; 54.28% female) residing in rural areas northeast China January August 2013, including fasting lipid profile anthropometric parameters. Logistic regression models were used to evaluate correlation AIP stroke. Category-free analysis was determine whether enhanced our capacity estimate stroke.Irrespective gender, independently associated...
Abstract Background Cardiovascular disease (CVD) brings high mortality and economic burden to patients, especially in rural areas. Simple, low-cost abdominal adiposity measures may help identify individuals with increased CVD risk. It is unclear that which obesity indices the best predict hypertensive people. Methods Northeast China Rural Health Study (NCRCHS) a prospective cohort study general population China. The examined cardiovascular health from 2013 2015, follow-up captured incidence...
This study is aimed at exploring the trends in prevalence, awareness, treatment, and control of hypertension rural northeast China from 2008 to 2018.Two successive cross-sectional surveys were conducted Liaoning areas 2018, which included 131520 10926 representative participants aged ≥ 40 years, respectively.Overall, age-standardized prevalence increased 44.7% 53.6%, male residents showed a faster pace increase 2.1-fold than female (25.5% vs. 10.6%) 2018. Moreover, mean systolic diastolic...
Identifying risk factors for atrial fibrillation (AF) and evaluating their impact are essential to avoid the occurrence of adverse events. However, few studies date have explored prevalence, factors, prognosis AF in hypertensive patients. The objective this study was investigate epidemiology a population determine relationship between all-cause mortality. At baseline, total 8541 Chinese patients with hypertension were enrolled from Northeast Rural Cardiovascular Health Study. A logistic...
First-degree atrioventricular block (AVB) has traditionally been regarded as a benign condition but recent studies have challenged this conception. Prevalence of 1-2% reported in developed countries Asia. However, no epidemiologic established the prevalence first-degree AVB developing countries. The aim study was to investigate rural northeast China and identify associated risk factors.This cross-sectional undertaken from September 2017 May 2018 areas Liaoning Province. It involved 10,926...
Objective: To investigate whether ECG left ventricular hypertrophy (ECG-LVH) has prognostic value independent of echocardiography LVH (Echo-LVH). Methods: Participants ( N = 9744, mean age, 53.81 ± 10.49 years and 45.5% male) from the Northeast China Rural Cardiovascular Health Study were included. Associations between Echo-LVH (sex-specific mass normalized to BSA) ECG-LVH (diagnosed using Cornell-voltage duration product) adverse outcomes evaluated Cox regression. The for predicting events...
Abstract Background Accurately predicting the risk of atherosclerotic cardiovascular disease (ASCVD) is crucial for implementing individualized prevention strategies and improving patient outcomes. Our objective to develop machine learning (ML)-based models ASCVD in a prospective Chinese population compare their performance with conventional regression models. Methods A hybrid dataset consisting 551 features was used, including 98 demographic, behavioral, psychological features, 444...
Abstract Objective: To gain more comprehensive understanding of metabolic syndrome (Mets) among in general Chinese population. Design: Cross-sectional study. Mets was defined by three widely accepted definitions including modified Adults Treatment Panel (ATP) III criteria, International Diabetes Federation (IDF) criteria and harmonized definition. Risk factors were evaluated using multivariate logistic regression. Setting: Nineteen rural villages northeast China. Participants: The survey...
To evaluate the up-to-date epidemiology of diabetes in northeast China.The cross-sectional study was conducted between September 2017 and March 2019 using a multistage, stratified cluster random sampling method. 18 796 participants (28.9% urban 71.1% rural) aged ≥40 years were enrolled. Diabetes pre-diabetes diagnosed according to history, fasting plasma glucose (FPG) glycosylated haemoglobin A1c (HbA1c) levels.The prevalence 17.1%, higher than rural residents (20.2% vs 15.8%, p<0.001)....
Objective To investigate the prognostic significance of first-degree atrioventricular block (AVB) in Asian populations. Design and setting Participants (N=9634) from Northeast China Rural Cardiovascular Health Study were included. The AVB was defined as PR (from beginning P wave to QRS complex on an electrocardiogram) interval >200 ms, primary composite outcome (all events) included new onset cardiovascular disease (CVD) mortality. Cox regression restricted cubic spline used identify...
Objective: To explore the prevalence and risk factors of ischemic stroke in rural areas Liaoning province. Methods: The study was a cross-sectional survey. From September 2017 to May 2018, total 10 926 residents aged ≥40 years were investigated Chaoyang county, Lingyuan, Liaoyang county Donggang city investigation included questionnaire survey, physical examination laboratory examination.Univariate multivariate logistic regression models used analyze stroke. Results: province 5.51% (602/10...
Abstract Background Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a novel inflammatory marker of inflammation and oxidative stress has been used predict multiple inflammation-related diseases, but data relative diabetes mellitus are lacking. Hence, our study aimed explore the impact MHR on its value improve risk stratification prevention in large cohort general Chinese population. Method This selected 8142 (males: 45.76%) participants who participated rural cardiovascular...
Determining risk factors of cardiovascular disease (CVD)-related mortality and evaluating their influence are important for effectively reducing corresponding mortality. However, few research findings have estimated the relationship between atrial fibrillation (AF) CVD-related among hypertension individuals. The objective this study was to investigate epidemiology AF in a population determine Using multistage, stratified, cluster random sampling method, prospective cohort with median...