Michael Höfinger
A5091364329- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Balance, Gait, and Falls Prevention
- Spinal Cord Injury Research
- COVID-19 epidemiological studies
- Injury Epidemiology and Prevention
Ludwig-Maximilians-Universität München
2021-2024
Fraunhofer Institute for Translational Medicine and Pharmacology
2023
German Center for Infection Research
2022
LMU Klinikum
2022
Quantitative serological assays detecting response to SARS-CoV-2 are needed quantify immunity. This study analyzed the performance and correlation of two quantitative anti-S1 in oligo-/asymptomatic individuals from a population-based cohort.In total, 362 plasma samples (108 with reverse transcription-polymerase chain reaction [RT-PCR]-positive pharyngeal swabs, 111 negative controls, 143 positive serology without confirmation by RT-PCR) were tested (Euroimmun Anti-SARS-CoV-2 QuantiVac...
Risk factors for disease progression and severity of SARS-CoV-2 infections require an understanding acute long-term virological immunological dynamics. Fifty-one RT-PCR positive COVID-19 outpatients were recruited between May December 2020 in Munich, Germany, followed up at multiple defined timepoints to one year. viral culture performed seroresponses measured. Participants classified applying the WHO clinical scale. Short symptom test time (median 5.0 days; p = 0.0016) high loads (VL;...
Background: The Balance Error Scoring System (BESS) is a commonly used method for clinically evaluating balance after traumatic brain injury. utilization of force plates, characterized by their cost-effectiveness and portability, facilitates the integration instrumentation into BESS protocol. Despite enhanced precision associated with instrumented measures, there remains need to determine clinical significance feasibility such measures within pediatric cohorts. Objective: To report...
Measuring specific anti-SARS-CoV-2 antibodies has become one of the main epidemiological tools to survey ongoing SARS-CoV-2 pandemic, but also vaccination response. The WHO made available a set well-characterized samples derived from recovered individuals allow normalization between different quantitative anti-Spike assays defined Binding Antibody Units (BAU).To assess sero-responses longitudinally, cohort ninety-nine RT-PCR positive subjects was followed up together with forty-five...
Population-based serological studies allow to estimate prevalence of SARS-CoV-2 infections despite a substantial number mild or asymptomatic disease courses. This became even more relevant for decision making after vaccination started. The KoCo19 cohort tracks the pandemic progress in Munich general population over two years, setting it apart Europe.Recruitment occurred during initial wave, including 5313 participants above 13 years from private households Munich. Four follow-ups were held...