- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Kruppel-like factors research
- Connective Tissue Growth Factor Research
- Acute Myeloid Leukemia Research
- Bone health and osteoporosis research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Systemic Sclerosis and Related Diseases
- Extracellular vesicles in disease
- Bladder and Urothelial Cancer Treatments
- Cell Adhesion Molecules Research
- DNA Repair Mechanisms
- RNA Research and Splicing
- Biomarkers in Disease Mechanisms
- Pregnancy-related medical research
- Renal and Vascular Pathologies
- Muscle Physiology and Disorders
Zhejiang University
2021-2024
Hangzhou First People's Hospital
2021-2024
Zhejiang Chinese Medical University
2021-2023
Southern Medical University
2020
Nanfang Hospital
2020
Nanjing Medical University
2007-2012
Jiangsu Province Hospital
2012
Background: Intracranial atherosclerotic stenosis (ICAS) is a common cause of first and recurrent ischemic stroke worldwide. Circular RNAs (circRNA)s have been recently suggested as candidate biomarkers in diagnosing prognosis stroke. A few circRNAs even serve therapeutic targets that improves neurological function after However, the roles ICAS caused (ICAS-stroke) not fully understood. Therefore, this study, we attempted to find some clues by investigating different expression profiles...
Cerebral ischemic stroke (CIS) is the most common type of stroke, which highly hazardous. This investigation aims to analyze correlation miR-497 with CIS, so as provide reliable evidence for clinical response CIS and lay a solid foundation follow-up research. Eighty-nine patients 39 concurrent physical examinees selected between June 2017 October 2018 were enrolled research participants. Additionally, SD rats increased expression normal purchased modeling observe implications in well water...
Introduction: Congenital muscular dystrophy (CMD) is a group of early-onset disorders with clinical and genetic heterogeneity. Patients always present muscle weakness typically from birth to early infancy, delay or arrest gross motor development, joint and/or spinal rigidity. There are various genes related the development CMD. Among them, mutations in integrin alpha 7 ( ITGA7 ) rare subtype. The identification disease-causing facilitates diagnosis treatment Methods: We screened four people...
Objective: To analyze the genetic mutations and clinical features of subtypes classical BCR-ABL-negative myeloproliferative neoplasm (MPN) . Methods: Mutations 108 newly diagnosed MPN patients [including 55 with essential thrombocytopenia (ET) , 24 polycythemia vera (PV) 29 primary myelofibrosis (PMF) ] were identified using next-generation sequencing 127-gene panel, relationship between gene analyzed. Results: Total 211 in 32 genes detected 100 (92.59% ) per capita carried (1.96±1.32)...