A5023806082- Gout, Hyperuricemia, Uric Acid
- Case Reports on Hematomas
- Urticaria and Related Conditions
- Spondyloarthritis Studies and Treatments
- Inflammasome and immune disorders
- Musculoskeletal synovial abnormalities and treatments
- Alcohol Consumption and Health Effects
- Hepatitis C virus research
- Adolescent and Pediatric Healthcare
- Bone and Joint Diseases
- Veterinary medicine and infectious diseases
- Autoimmune and Inflammatory Disorders Research
- Delphi Technique in Research
- Hematological disorders and diagnostics
- Endometriosis Research and Treatment
- Biomarkers in Disease Mechanisms
- Systemic Lupus Erythematosus Research
- Pharmaceutical Practices and Patient Outcomes
- Bone health and osteoporosis research
- Gastroesophageal reflux and treatments
- Economic and Environmental Valuation
- Eosinophilic Disorders and Syndromes
- Infectious Diseases and Tuberculosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Systemic Sclerosis and Related Diseases
Centre Hospitalier Chrétien
2016-2024
Maastricht University Medical Centre
2013-2024
University Medical Center
2016-2022
Maastricht University
2012-2022
University Hospital and Clinics
2016
Centre Hospitalier Universitaire de Liège
2013-2015
Columbia University Irving Medical Center
2014
Amsterdam UMC Location University of Amsterdam
2014
Atrium Medisch Centrum Parkstad
2014
Medical University of Vienna
2014
<h3>Objective</h3> There is a lack of standardisation in the terminology used to describe gout. The aim this project was develop consensus statement describing recommended nomenclature for disease states <h3>Methods</h3> A content analysis gout-related articles from rheumatology and general internal medicine journals published over 5-year period identified potential labels commonly assigned them. Based on these findings, experts gout were invited participate Delphi exercise face-to-face...
To evaluate the efficacy and safety of anakinra in treating acute gout flares a randomized, double-blind, placebo-controlled, active comparator, non-inferiority (NI) trial.
Objective. Gout has been associated with a large number of co-morbidities. As yet, no co-morbidity measure validated for use in clinical studies gout. This study aims to evaluate the content and construct validity Rheumatic Diseases Comorbidity Index (RDCI) gout-specifically modified RDCI (mRDCI) patients Methods. In cross-sectional sample 122 gout, data on co-morbidities were obtained during an interview, chart review examination. The used compute RDCI/mRDCI, simple count, Charlson (CCI)...
Research findings in gout result predominantly from studies about men and might not be generalizable to women. To improve insight into sex differences gout, our study compared clinical characteristics comorbidities of female male patients with explored the influence menopause on these differences.Data referred 2 rheumatology clinics diagnosed were used. Clinical each univariately. Sex difference further multivariate logistic regression analyses adjusting for age, BMI, smoking, alcohol...
To estimate costs of illness in a cross-sectional cohort patients with gout attending an outpatient rheumatology clinic, and to evaluate which factors contribute higher costs.Altogether, 126 were clinically assessed. They completed series questionnaires. Health resource use was collected using self-report questionnaire that cross-checked the electronic patient file. Productivity loss assessed by Work Activity Impairment Questionnaire, addressing absenteeism presenteeism. Resource...
Abstract Background Patients with obstructive sleep apnea (OSA) might be at risk of gout because pathophysiological mechanisms that can lead to hyperuricemia and eventually or shared factors between both diseases. The objective the present study was investigate in patients OSA. Methods A population-based case-control using UK Clinical Practice Research Datalink GOLD including all aged 40 years older a first diagnosis 1987 2014. Gout cases were matched by year birth, sex, practice non-gout...
Chronic obstructive pulmonary disease (COPD) is a risk factor for osteoporosis. Our objective to determine if functional indices associated with emphysema on function tests (DLCO-diffusion capacity of the lung CO-; DLCO/AV-DLCO corrected alveolar volume- and TLC-total capacity), considered alone or together, can identify COPD patients 90 underwent dual-energy X-ray absorptiometry (DEXA) tests. 26% were osteoporotic. In univariate analysis, each parameter emphysema, analyzed separately, was...
The aim of this study is to develop and assess usability a web-based patient-tailored tool support adherence urate-lowering therapy (ULT) among gout patients in clinical setting.
Objective To compare outcomes of 2 gout clinics that implemented different treatment strategies. Methods Patients newly diagnosed with and a follow‐up 9–15 months were included. Co‐primary the proportion patients reaching serum uric acid ( UA ) ≤0.36 mmoles/liter free flares. Secondary requiring intensification experiencing adverse events. One clinic adopted strict (≤0.30 target) strategy, early addition uricosuric to allopurinol, other patient‐centered (PC) strategy emphasizing shared...
Aim Shared decision-making improves patients’ experiences with care, satisfaction management decisions and possibly health outcomes. This study describes the development of a decision aid (DA) that supports patients gout their physicians in face-to-face clinical setting to (a) decide whether or not (re)start urate-lowering therapy (ULT) (b) agree on preferred ULT. Methods Recommendations International Patient Decision Aid Standards group guided development. A steering experts services...
Objective To assess health- and patient-centered outcomes in gout across Europe, explore patient-, care-, country-level characteristics associated with these outcomes. Methods Patients self-reported physician-diagnosed from 14 European countries completed an online survey. Multivariable mixed-effect logistic linear regressions were computed for health (gout flare recurrence) (patient satisfaction current medication, unaddressed goals), accounting clustering within countries. The role of...
Objective. To investigate construct validity of radiographic damage the feet in gout. Methods. Radiographs were scored using Sharp/van der Heijde method. Factors associated with investigated by a negative binomial model, and contribution to health linear regressions. Results. Age, disease duration, serum uric acid, tophi being erosive erosion score. Tophi joint space narrowing. Erosions (β 0.47, 95% CI 0.09–0.84) physical function, but was not overall health. Conclusion. Our results support...
Background: Adherence to prescribed urate-lowering therapy (ULT) among gout patients is considered be the poorest of all chronic conditions. eHealth programs can a possible opportunity foster ULT adherence. Objectives: This study describes development and usability evaluation web-based tool support adherence patients, specifically designed for complement usual care. Methods: The Integrated Change (I-Change) model was used as theoretical basis development. combines various socio-cognitive...
<h3>Background</h3> Adherence with osteoporosis medications is poor and suboptimal. Understanding patients' preferences may be a first step to improve adherence therapy. Over recent years, there has been an increased interest in the use of discrete-choice experiments (DCE) elicit preferences. The number medication attributes identified literature however exceeds what one find possible pilot DCE. Hence need gain insight into most relevant for treatment. <h3>Objectives</h3> This study aims...