A5049073273- Neural dynamics and brain function
- Neuroscience and Music Perception
- EEG and Brain-Computer Interfaces
- Neurobiology of Language and Bilingualism
- Neural and Behavioral Psychology Studies
- Multisensory perception and integration
- Action Observation and Synchronization
- Phonetics and Phonology Research
- Functional Brain Connectivity Studies
- Reading and Literacy Development
- Liver Disease Diagnosis and Treatment
- Topic Modeling
- Advanced Graph Neural Networks
- Dialysis and Renal Disease Management
- Neural Networks and Applications
- Hepatitis B Virus Studies
- Visual Attention and Saliency Detection
- Intelligent Tutoring Systems and Adaptive Learning
- Hepatitis C virus research
- Hearing Impairment and Communication
- Visual perception and processing mechanisms
- DNA Repair Mechanisms
- Language Development and Disorders
- Cognitive Functions and Memory
- Hearing Loss and Rehabilitation
New York University Shanghai
2016-2025
East China Normal University
2018-2025
New York University
2012-2024
Zhengzhou University
2024
China West Normal University
2024
Peking University
2019-2023
Ministry of Education of the People's Republic of China
2022-2023
Zhejiang University
2023
Zhejiang Lab
2023
Guiyang Medical University
2023
Reconstructing intended speech from neural activity using brain-computer interfaces holds great promises for people with severe production deficits. While decoding overt has progressed, imagined met limited success, mainly because the associated signals are weak and variable compared to speech, hence difficult decode by learning algorithms. We obtained three electrocorticography datasets 13 patients, electrodes implanted epilepsy evaluation, who performed tasks. Based on recent theories of...
The classical concept of efference copies in the context internal forward models has stimulated productive research cognitive science and neuroscience. There are compelling reasons to argue for such a mechanism, but finding direct evidence human brain remains difficult. Here we investigate dynamics from an unconventional angle: mental imagery, assessed while recording high temporal resolution neuronal activity using magnetoencephalography. We compare two overt covert tasks; our covert,...
The computational role of efference copies is widely appreciated in action and perception research, but their properties for speech processing remain murky. We tested the functional specificity auditory using magnetoencephalography recordings an unconventional pairing: used a classical cognitive manipulation (mental imagery--to elicit internal simulation estimation) with well-established experimental paradigm (one shot repetition--to assess neuronal specificity). Participants performed tasks...
The neural basis of mental imagery has been investigated by localizing the underlying networks, mostly in motor and perceptual systems, separately. However, how modality-specific representations are top-down induced action perception systems interact context is not well understood. Imagined speech production ("articulation imagery"), which induces kinesthetic feeling articulator movement its auditory consequences, provides a new angle because concurrent involvement systems. On previous...
Abstract Voice or speaker recognition is critical in a wide variety of social contexts. In this study, we investigated the contributions acoustic, phonological, lexical and semantic information toward voice recognition. Native English speaking participants were trained to recognize five speakers conditions: non-speech, Mandarin, German, pseudo-English English. We showed that significantly improved as more became available, from purely acoustic features non-speech additional phonological...
Natural sounds convey perceptually relevant information over multiple timescales, and the necessary extraction of multi-timescale requires auditory system to work distinct ranges. The simplest hypothesis suggests that temporal modulations are encoded in an equivalent manner within a reasonable intermediate range. We show human selectively preferentially tracks acoustic dynamics concurrently at 2 timescales corresponding neurophysiological theta band (4–7 Hz) gamma ranges (31–45 but, contrary...
Abstract Parsing continuous acoustic streams into perceptual units is fundamental to auditory perception. Previous studies have uncovered a cortical entrainment mechanism in the delta and theta bands (~1–8 Hz) that correlates with formation of speech, music, other quasi‐rhythmic stimuli. Whether oscillations delta‐theta are passively entrained by regular patterns or play an active role parsing stream debated. Here, we investigate using novel stimuli 1/f modulation spectra. These signals no...
A critical subroutine of self-monitoring during speech production is to detect any deviance between expected and actual auditory feedback. Here we investigated the associated neural dynamics using MEG recording in mental-imagery-of-speech paradigms. Participants covertly articulated vowel /a/; their own (individually recorded) was played back, with parametric manipulation four levels pitch shift, crossed onset delay. nonmonotonic function observed early responses when delay shorter than 100...
Abstract Natural sounds contain information on multiple timescales, so the auditory system must analyze and integrate acoustic those different scales to extract behaviorally relevant information. However, this multi-scale process in is not widely investigated literature existing models of temporal integration are mainly built upon detection or recognition tasks a single timescale. Here we use paradigm requiring processing relatively ‘local’ ‘global’ provide evidence suggesting that extracts...
To flexibly convey meaning, the human language faculty iteratively combines smaller units such as words into larger structures phrases based on grammatical principles. During comprehension, however, it remains unclear how brain encodes relationship between and them phrases. One hypothesis is that internal principles governing generation are also used to parse hierarchical syntactic structure of spoken language. An alternative suggests, in contrast, decoding during comprehension solely relies...
Although growing evidence has demonstrated that the long noncoding RNA DLEU1 is involved in progression of various cancers, its functional role and underlying mechanisms have not been explored cervical cancer (CC). In this study, we found was up-regulated both CC tissues cell lines, overexpression significantly correlated with shorter patient survival. Knockdown suppressed proliferation invasion, whereas promoted invasion cells. Bioinformatics analysis used to elucidate potential correlation...
Abstract Ovarian cancer is the most lethal gynecological malignancy worldwide with high metastasis and poor prognosis rates. Cancer‐associated fibroblasts (CAFs), a heterogeneous population of cells that constitutes major component tumor microenvironment, secrete extracellular vesicles (EVs) loading proteins, lipids, RNAs to promote tumorigenesis. However, specific roles CAF‐derived proteins contained in EVs ovarian remain poorly understood at present. Using gene expression microarray...
Abstract Background Acquired radioresistance of cancer cells remains a fundamental barrier to attaining the maximal efficacy radiotherapy for treatment breast cancer. Anti-apoptotic proteins, such as Bcl-2 and Bcl-xL, play an important role in cells. In present study, we aimed determine if ABT-737, BH3-only mimic, could reverse acquired cell line MDA-MB-231R by targeting Bcl-xL. Methods The radiosensitivity MDA-MB-231 was compared using colony formation assays. Reverse-transcription PCR...
Objective: Non-alcoholic fatty liver disease (NAFLD), previously thought to predominantly affect obese individuals, has also been shown occur in subjects who have a relatively normal body mass index (BMI). Due the BMI, non-obese NAFLD are easily be ignored and eventually lead potential injuries. Methods: A population-based cross-sectional study was conducted on 1608 cases with serum alanine aminotransferase (ALT) levels were divided into an group (BMI ≥ 25 kg/m 2 ) < ). diagnosed by...
With the planning and implementation of large wind solar bases in desert, Gobi, wilderness areas, state is intensifying efforts to build a new energy supply consumption system, which poses higher demands on regulation support capabilities power grid. Concentrated (CSP) generation integrates characteristics synchronous machine, storage, energy, holds unique advantages diversified source system system. It will significantly impact technological pathway for low-carbon transformation. This paper...
It is debated whether cortical responses matching the time scales of phrases and sentences mediate mental construction syntactic chunks or are simply caused by semantic properties words. Here, we investigate to what extent delta-band neural speech can be explained relatedness between To dissociate contribution from sentential structures, participants listened sentence sequences paired-word in which semantically related words repeated at 1 Hz. Semantic 2 types was quantified using a word2vec...