A5056253998- Inflammatory Bowel Disease
- Microscopic Colitis
- Acute Myocardial Infarction Research
- Eosinophilic Esophagitis
- Atrial Fibrillation Management and Outcomes
- Liver Diseases and Immunity
- Clostridium difficile and Clostridium perfringens research
- Acute Lymphoblastic Leukemia research
- Circadian rhythm and melatonin
- Clinical Nutrition and Gastroenterology
- Diverticular Disease and Complications
- Gastroesophageal reflux and treatments
- Neutropenia and Cancer Infections
- Obstructive Sleep Apnea Research
- Appendicitis Diagnosis and Management
- Vasculitis and related conditions
- Inflammatory Biomarkers in Disease Prognosis
- Medical Device Sterilization and Disinfection
- Health and Medical Studies
- Cancer Immunotherapy and Biomarkers
- Immunodeficiency and Autoimmune Disorders
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Hepatocellular Carcinoma Treatment and Prognosis
- Pregnancy and Medication Impact
Monash University
2020-2024
Western Health
2023-2024
The Alfred Hospital
2023-2024
Eastern Health
2019-2021
Box Hill Hospital
2019-2020
St Vincent's Hospital
2016-2017
The residual risk of colectomy after infliximab salvage in steroid-refractory acute severe ulcerative colitis (ASUC) is required to inform the need for subsequent maintenance biologic therapy. aim this study was determine dynamic response common serum biomarkers and assess their utility predicting colectomy.A retrospective single-center cohort conducted on all patients who received ASUC between January 1, 2010, July 31, 2019. Biomarkers were assessed admission days 1 3 post infliximab,...
Summary Background There are safety concerns regarding immunomodulators (thiopurines and methotrexate) for treatment of inflammatory bowel disease (IBD). Aim To compare the long‐term tolerability, persistence thiopurine methotrexate therapy in IBD. Methods A retrospective cohort study was performed at two hospitals between 1 January 2004 31 December 2016 patients commenced on thiopurines or Treatment discontinuation rates, intolerances activity were obtained from medical records. Results 782...
Aims To develop and validate a new scale for mucosal visualization of the upper gastrointestinal tract during esophagogastroduodenoscopy (EGD), Gastroscopy RAte Cleanliness Evaluation (GRACE), as quality standard tool through application standardized, reliable, validated scoring system.
While patients with inflammatory bowel disease are known to be at increased risk of venous thromboembolism, the arterial thrombosis is less well recognized. Here, we describe case a middle-aged female recent diagnosis Crohn's who presented her local emergency department acute abdominal pain. Subsequent investigations revealed thrombus in superior mesenteric artery resulting multi-organ infarction requiring major intra-abdominal surgery and extensive resection segments small large bowel.
Background Aminosalicylates are widely used in ulcerative colitis (UC) and often continued despite treatment escalation, perhaps given a lack of evidence or consensus guiding dose reduction cessation. The aim was to compare long-term outcomes patients who escalated either discontinued aminosalicylate therapy. Methods Consecutive diagnosed with UC ≥1 year prior escalation immunomodulator biologic therapy while concurrently taking aminosalicylates, were compared based on discontinuation versus...
Abstract Ischaemic heart disease is the leading cause of death worldwide. Age strongest risk factor, yet older patients are consistently underrepresented in clinical trials. With an ageing population, knowledge evidence base for treatment with acute coronary syndrome (ACS) crucial. As people age, their responses to medications change, and they may become more susceptible adverse effects cardiovascular medications. Management ACS be further complicated by presence comorbidities, polypharmacy...
drugs they prescribe would tend to vitiate the " rapport existing between doctor and patient ?Expecting trust or be possible in face of such callous indifference safety patients others seems utterly incomprehensible.Equally dangerous is habit some doctors not offering information on whether small large amounts alcohol can alter effectiveness any drug its safety.-I am, etc., London S.W. 1.
An 85-year-old man with Child-Pugh A cirrhosis secondary to non-alcoholic steatohepatitis presented casualty four days of painless haematochezia dark blood without haemodynamic compromise. This was in the setting receiving stereotactic body radiation therapy (SBRT) as treatment for his hepatocellular carcinoma (HCC). He found have haemorrhagic colitis which treated argon plasma coagulation (APC). Our case demonstrates importance considering induced a cause lower gastrointestinal bleeding...