A5004442871- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Stress Responses and Cortisol
- Mental Health Research Topics
- Hypothalamic control of reproductive hormones
- Neuroendocrine regulation and behavior
- Behavioral Health and Interventions
- Neural and Behavioral Psychology Studies
- Advanced Neuroimaging Techniques and Applications
- Death Anxiety and Social Exclusion
- Advanced MRI Techniques and Applications
- Digital Mental Health Interventions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Advanced Causal Inference Techniques
- Personality Traits and Psychology
- Psychological Well-being and Life Satisfaction
- Cognitive Abilities and Testing
- Cultural Differences and Values
- Decision-Making and Behavioral Economics
- Attachment and Relationship Dynamics
- Neural dynamics and brain function
- Resilience and Mental Health
- Economic and Environmental Valuation
- Health, Environment, Cognitive Aging
- Biomedical and Engineering Education
Harvard University
2019-2025
Harvard University Press
2019-2025
Center for Pain and the Brain
2021-2022
University of Oregon
2015-2022
University of Sussex
2021
Brighton and Sussex Medical School
2021
University of Lausanne
2019
University of North Carolina at Chapel Hill
2019
Massachusetts Institute of Technology
2017
University of Cambridge
2017
Over the past decade extensive research has examined segregation of human brain into large-scale functional networks. The resulting network maps, i.e. parcellations, are now commonly used for a priori identification However, use these particularly in developmental and clinical samples, hinges on four fundamental assumptions: (1) various parcellations equally able to recover networks interest; (2) adult-derived well represent children's brains; (3) properties, such as within-network...
Adolescence is characterized by the maturation of cortical microstructure and connectivity supporting complex cognition behavior. Axonal myelination influences brain during development enhancing neural signaling speed inhibiting plasticity. However, maturational timing human adolescence remains poorly understood. Here, we take advantage recent advances in high-resolution T1w/T2w mapping methods, including principled correction B1+ transmit field effects, using data from Human Connectome...
Abstract Childhood socioeconomic status (SES) is related to disparities in the development of both language and executive functioning (EF) skills. Emerging evidence suggests that may precede provide necessary scaffolding for EF early childhood. The present preregistered study investigates how these skills co‐develop longitudinally childhood whether explains relationship between SES development. A socioeconomically diverse sample 305 children completed repeated assessments (sentence...
The human brain is remarkably plastic. changes dramatically across development, with ongoing functional development continuing well into the third decade of life and substantial occurring again in older age. Dynamic function are thought to underlie innumerable cognition, emotion, behavior that occur development. also response experience, which raises important questions about how environment influences developing brain. Longitudinal magnetic resonance imaging (fMRI) studies an essential...
Exposure to stressful life events is strongly associated with internalizing psychopathology, and identifying factors that reduce vulnerability stress-related problems critical for development of early interventions. Drawing on research from affective science, we tested whether high emotion differentiation—the ability specifically identify one’s feelings—buffers adolescents developing symptoms when exposed stress. Thirty completed a laboratory measure differentiation before an intensive...
Longitudinal data are becoming increasingly available in developmental neuroimaging. To maximize the promise of this wealth information on how biology, behavior, and cognition change over time, there is a need to incorporate broad rigorous training longitudinal methods into repertoire neuroscientists. Fortunately, these models have an incredibly rich tradition broader sciences that we can draw from. Here, provide primer models, written beginner-friendly (and slightly irreverent) manner, with...
Recent work demonstrating low test-retest reliability of neural activation during fMRI tasks raises questions about the utility task-based for study individual variation in brain function. Two possible sources instability BOLD signal over time are noise or measurement error instrument, and meaningful across within-individuals construct itself—brain elicited tasks. Examining contribution these two unreliability task-evoked activity has far-reaching implications cognitive neuroscience. If...
Few online interventions targeting anxiety and depression in university students are designed for universal delivery, none group-level delivery. This randomized controlled trial (NCT No. 04361045) examined the effectiveness of such a prevention program.
Multivariate machine learning techniques are a promising set of tools for identifying complex brain-behavior associations. However, failure to replicate results from these methods across samples has hampered their clinical relevance. Here we aimed delineate dimensions brain functional connectivity that associated with child psychiatric symptoms in two large and independent cohorts: the Adolescent Brain Cognitive Development (ABCD) Study Generation R (total n = 6935). Using sparse canonical...
Early pubertal timing has consistently been associated with internalizing psychopathology in adolescent girls. Here, we aimed to examine whether the association between and mental health outcomes varies by measurement of psychopathology, differs adrenarcheal gonadarcheal processes, is stronger concurrently or prospectively. We assessed 174 female adolescents (age 10.0-13.0 at Time 1) twice, an 18-month interval. Participants provided self-reported assessments depression/anxiety symptoms...
Puberty is associated with hormone level changes that influence white matter development. It remains unclear how pubertal stage and hormones uniquely relate to microstructure Further, it if tracts develop along a hierarchical sensorimotor-association (S-A) axis, similar other aspects of brain We used the Human Connectome Project in Development cross-sectional sample 1,131 youth (aged 5-21 years) investigate unique contributions sex, age, stage, DHEA, testosterone, estradiol, progesterone...
Research in developmental psychology suggests that self-concept formation and mentalizing capacities, along with their neural foundations, show significant change during adolescence. Perspective-taking tendencies are also believed to increase adolescence, supporting the refinement of prosocial behavior demands increasingly complex social relationships. To explore development of, relationship between, these processes early adolescent girls (N = 172) completed a measure perspective-taking...
Objective. Low socioeconomic status (SES) during childhood is associated with higher levels of youth psychopathology. However, limited longitudinal work has examined the role both household and neighborhood SES in shaping mental health trajectories over time using large population-based data. The goal present study was to characterize associations between changes problems early adolescence.Methods. We investigated independent joint income-to-needs ratio, parent educational attainment,...
Abstract Background Low socioeconomic status (SES) during childhood is associated with higher levels of youth psychopathology. However, limited longitudinal work has examined the role both household and neighborhood SES in shaping mental health trajectories over time using population‐based data. The goal present study was to characterize associations between changes problems early adolescence. Methods We investigated independent joint income‐to‐needs ratio, parent educational attainment,...
Objective Late-life depression (LLD) is a common and debilitating condition among older adults. Cognitive behavioral therapy (CBT) has strong empirical support for the treatment of in all ages, including LLD. In teaching patients to identify, monitor, challenge negative patterns their thinking, CBT LLD relies heavily on cognitive processes and, particular, executive functioning, such as planning, sequencing, organizing, selectively inhibiting information. It may be that effectiveness lies...
Background Adolescence is characterized by substantial changes in sleep behavior, heightened exposure to stressful life events (SLEs), and elevated risk for internalizing problems like anxiety depression. Although SLEs are consistently associated with the onset of psychopathology, mechanisms underlying this relationship remain poorly understood, especially at within‐person level. Here, we leverage a high‐frequency longitudinal design examine as potential mechanism linking increases...
Early adolescence is marked by puberty, and also a time of flux in self-perception. However, there limited research on the neural correlates self-evaluation relation to pubertal development. The current study examined relationships between activation during social traits maturation (age development) community sample female adolescents. Participants (N = 143; age M 11.65, range 10.0–13.0) completed functional MRI task which they judged self-descriptiveness adjectives for prosocial, antisocial...
Pubertal processes are associated with structural brain development, but studies have produced inconsistent findings that may relate to different measurements of puberty. Measuring both hormones and physical characteristics is important for capturing variation in neurobiological development. The current study explored associations between cortical thickness latent factors from multi-method pubertal data 174 early adolescent girls aged 10-13 years the Transitions Adolescent Girls (TAG) Study....
The longitudinal study of typical neurodevelopment is key for understanding deviations due to specific factors, such as psychopathology. However, research utilizing repeated measurements remains scarce. Resting-state functional magnetic resonance imaging (MRI) studies have traditionally examined connectivity ‘static’ during the measurement period. In contrast, dynamic approaches offer a more comprehensive representation by allowing different configurations (time varying connectivity)...