- Genetic diversity and population structure
- Archaeology and ancient environmental studies
- Genomics and Phylogenetic Studies
- Geology and Paleoclimatology Research
- Forensic and Genetic Research
- Yeasts and Rust Fungi Studies
- Plant Pathogens and Fungal Diseases
- Environmental DNA in Biodiversity Studies
- Atomic and Molecular Physics
- Wildlife Ecology and Conservation
- Advanced Chemical Physics Studies
- Horticultural and Viticultural Research
- Plant responses to water stress
- Genetic and phenotypic traits in livestock
- Pleistocene-Era Hominins and Archaeology
- Plant and Fungal Interactions Research
- Molecular Biology Techniques and Applications
- Botany and Plant Ecology Studies
- Forest Ecology and Biodiversity Studies
- Ancient and Medieval Archaeology Studies
- Tree-ring climate responses
- Radioactive Decay and Measurement Techniques
- Forensic Anthropology and Bioarchaeology Studies
- Paleopathology and ancient diseases
- Radiation Effects and Dosimetry
Centre d'Anthropobiologie et de Génomique de Toulouse
2023-2024
Université Toulouse III - Paul Sabatier
2018-2024
Centre National de la Recherche Scientifique
2018-2024
Laboratoire de Recherche en Sciences Végétales
2020-2024
Centre de Physiopathologie de Toulouse-Purpan
2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2023
AMIS - Laboratoire d'anthropologie moléculaire et imagerie de synthèse
2019-2020
Centre d'Études Scientifiques et Techniques d'Aquitaine
2011-2019
UMR BIOdiversity, GEnes & Communities
2011-2019
Université de Bordeaux
2011-2018
The horse is central to many Indigenous cultures across the American Southwest and Great Plains. However, when how horses were first integrated into lifeways remain contentious, with extant models derived largely from colonial records. We conducted an interdisciplinary study of assemblage historic archaeological remains, integrating genomic, isotopic, radiocarbon, paleopathological evidence. Archaeological modern North show strong Iberian genetic affinities, later influx British sources, but...
Abstract Horses revolutionized human history with fast mobility 1 . However, the timeline between their domestication and widespread integration as a means of transport remains contentious 2–4 Here we assemble collection 475 ancient horse genomes to assess period when these animals were first reshaped by agency in Eurasia. We find that reproductive control modern domestic lineage emerged around 2200 bce , through close-kin mating shortened generation times. Reproductive following severe...
Abstract Reconstructing the colonization and demographic dynamics that gave rise to extant forests is essential forecasts of forest responses environmental changes. Classical approaches map how population trees changed through space time largely rely on pollen distribution patterns, with only a limited number studies exploiting DNA molecules preserved in wooden tree archaeological subfossil remains. Here, we advance such analyses by applying high‐throughput ( HTS ) sequencing wood material...
How contemporary plant genomes originated and evolved is a fascinating question. One approach uses reference from extant species to reconstruct the sequence structure of their common ancestors over deep timescales. A second focuses on direct identification genomic changes at shorter timescale by sequencing ancient DNA preserved in subfossil remains. Merged within nascent field paleogenomics, these complementary approaches provide insights into evolutionary forces that shaped organization...
Abstract Multiplex PCR is a fast and cost‐effective technique allowing increased genotyping throughput of microsatellites. We developed two multiplexes for Quercus petraea Q. robur , 12‐plex EST‐SSRs (eSSRs) an 8‐plex genomic SSRs (gSSRs). studied the origin allele calling errors at human reader software levels. showed that robustness identification can be improved by binning on raw peak sizes prior to genetic data analysis. checked through simulation power these markers species delimitation...
This paper reports a high-resolution isotopic study of medieval horse mobility, revealing their origins and in-life mobility both regionally internationally. The animals were found in an unusual cemetery site within the City Westminster, London, England. Enamel strontium, oxygen, carbon isotope analysis 15 individuals provides information about likely place birth, diet, during first approximately 5 years life. Results show that at least seven horses originated outside Britain relatively cold...
Abstract Key message Mining genome-wide DNA sequences enabled the discovery of near-diagnostic markers for species assignment in four European white oaks ( Quercus petraea (Matt.) Liebl., pubescens Willd., pyrenaica and robur L.) despite their low interspecific differentiation. Near-diagnostic are almost fully fixed one absent three others. As a result, only handful needed identification, making this genetic assay very promising operational taxonomic procedure research forestry. Context...
Abstract European beech ( Fagus sylvatica L.) is one of the economically most important broadleaved tree species in Europe and has become a model for studying climate change effects on forests. Multiplex PCR microsatellites fast cost‐effective technique allowing high‐throughput genotyping. Here we present procedure used to develop two multiplex kits (8‐plexes) beech. We paid particular attention quality control throughout all steps development (null allele detection, error rate measurements,...
Disruption of species interactions is a key issue in climate change biology. Interactions involving forest trees may be particularly vulnerable due to evolutionary rate limitations imposed by long generation times. One mitigation strategy for such impacts Climate matching - the augmentation local native tree populations input from nonlocal currently experiencing predicted future climates. This controversial because potential cascading on locally adapted animal communities. We explored these...
Age profiling of archaeological bone assemblages can inform on past animal management practices, but is limited by the fragmentary nature fossil record and lack universal skeletal markers for age. DNA methylation clocks offer new, albeit challenging, alternatives estimating age-at-death ancient individuals. Here, we take advantage availability a clock based 31,836 CpG sites dental age in horses to assess predictions 84 remains. We evaluate our approach using whole-genome sequencing data...
The g factors of the first ${2}^{+}$ states and $B(E2)$ values ${(2}_{1}^{+}\ensuremath{\rightarrow}{0}_{1}^{+})$ transitions have been determined with high precision for all stable doubly even Zn isotopes employing combined technique projectile Coulomb excitation in inverse kinematics transient magnetic fields. In addition, this systematic study was supplemented by a measurement radioactive ${}^{62}\mathrm{Zn}$ ${(T}_{1/2}=9.2 h)$ formed an $\ensuremath{\alpha}$-transfer reaction...
Abstract We have designed two highly polymorphic microsatellite multiplexes for Larix decidua Mill (European larch), a coniferous tree species with fragmented distribution across Europe. The combine microsatellites previously the sister L. kaempferi and newly identified obtained by pyrosequencing of an enriched library subsequent marker candidate selection. As we wanted to target markers, only motifs high number repeats (≥12) were selected. An important proportion candidates presented...
In contrast to biological invasions, translocations of individuals within a species range are understudied, due difficulties in systematically detecting them. This results limited knowledge about the corresponding processes and uncertainties regarding status extant populations. European larch, forest tree whose fragmented native distribution is restricted Alps other Central mountains, has been massively planted for at least 300 years. Here we focus on genetic characterization having taken...
Abstract Whole genome characterizations of crop plants based on ancient DNA have provided unique keys for a better understanding the evolutionary origins modern cultivars, pace and mode selection underlying their adaptation to new environments production phenotypes interest. Although forests are among most biologically rich ecosystems earth represent fundamental resource human societies, no sequences been generated trees. This contrasts with generation multiple reference genomes important...
Abstract Pollen data are well established for quantitative climate reconstructions over long timescales, including the Holocene and older interglacials. However, anthropogenically induced environmental change in central Europe was strong during last 4 ka, challenging of this time period. Here we present based on pollen analyses evaluate them with peat humification record stable carbon isotopes Sphagnum plant material ( δ 13 C cellulose ). All were carried out same 7.5 m long, largely...
The northern coast of the Médoc between Soulac-sur-Mer and Montalivet-les-Bains has a rich archaeological heritage that is being directly impacted by coastal erosion. A series clay-peat palaeosols formed in ancient estuarine marshes holds evidence intensive occupation from Mesolithic until end Roman period. Within this framework, our research focused on two key sites La Lède du Gurp (Grayan-et-l'Hôpital) L'Amélie (Soulac-sur-Mer), where an interdisciplinary approach based comparison...
The field of ancient genomics has undergone a true revolution during the last decade. Input material, time requirements and processing costs have first limited number specimens amenable to genome sequencing. However, discovery that archaeological material such as petrosal bones can show increased DNA preservation rates, combined with advances in sequencing technologies, molecular methods for recovery degraded fragments bioinformatics, vastly expanded range samples compatible genome-wide...
Abstract Key message Appropriate silvicultural practices combined with the use of resistant Central European provenances can reduce prevalence larch canker caused by Lachnellula willkommii (R. Hartig) Dennis, a major disease affecting plantations in France. However, cascading translocations have resulted frequent admixture ( Larix decidua Mill.) and subsequent certification errors regarding origin plant material. Our study highlights urgent need to improve process seed orchards. Context The...
The ultra-short DNA molecules still preserved in archaeological remains can provide invaluable genetic information about past individuals, species and communities within the half to one-million-year time range. sequence data are, however, generally affected by post-mortem damage include specific patterns of nucleotide mis-incorporations, which help authentication. Recent work ancient mammals has shown that such also assess levels methylation CpG contexts. Despite pioneering barley sorghum,...
The g factor of the first ${2}^{+}$ state ${}^{54}\mathrm{Cr}$ was remeasured employing combined technique projectile Coulomb excitation in inverse kinematics and transient magnetic fields. value obtained, $g=+0.840(56),$ is significantly larger than previous data. new agrees better with a truncated large-scale shell model calculation. present result discussed context recently determined factors states ${}^{50}\mathrm{Cr}$ ${}^{52}\mathrm{Cr}$ as well $B(E2)$ values from lifetime measurements.