A5049487214- Health, Medicine and Society
- Musculoskeletal pain and rehabilitation
- Workplace Health and Well-being
- Healthcare Systems and Practices
- Healthcare professionals’ stress and burnout
- Sleep and Work-Related Fatigue
- Occupational Health and Safety Research
- Aging, Elder Care, and Social Issues
- COVID-19 and Mental Health
- Employment and Welfare Studies
- Social Policies and Family
- Occupational exposure and asthma
- Health, psychology, and well-being
- Injury Epidemiology and Prevention
- Air Quality and Health Impacts
- Phytoestrogen effects and research
- Contact Dermatitis and Allergies
- Trauma and Emergency Care Studies
- Occupational and environmental lung diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Vaccine Coverage and Hesitancy
- Sleep and related disorders
- Epigenetics and DNA Methylation
- Influenza Virus Research Studies
- Occupational Health and Performance
Université Claude Bernard Lyon 1
2014-2024
Centre Hospitalier Universitaire de Saint-Étienne
2015-2024
Institute Cancer De La Loire Lucien Neuwirth
2014-2024
Université Gustave Eiffel
2021-2024
Université Jean Monnet
2013-2024
Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement
2015-2024
Fondazione Edmund Mach
2024
Université de Lyon
2012-2023
Institut Français
2018
Centre for Advanced Study
2018
HERG K+channels, besides contributing to regulate cardiac and neuronal excitability, are preferentially expressed in tumour cell lines of different histogenesis, where their role the development maintenance neoplastic phenotype is under study. We show here that both herg gene protein with high frequency primary human endometrial cancers, as compared normal hyperplastic endometrium. RT-PCR immunohistochemistry, using specific anti-HERG antibodies developed our laboratory, were applied tissue...
Background A strong association between workplace bullying and subsequent anxiety depression, indicated by empirical research, suggests that is an aetiological factor for mental health problems.
Objectives To investigate the risk of renal cell carcinoma (RCC) in Central and Eastern Europe relation to exposure known suspected carcinogenic metals. Methods During 1999–2003, authors conducted a hospital-based study Czech Republic, Poland, Romania Russia, including 1097 cases RCC 1476 controls. Occupational arsenic, cadmium, chromium(III), chromium(VI), lead nickel was assessed by teams local industrial hygiene experts, based on detailed occupational questionnaires. Results The ORs for...
This study investigated the relation between working conditions, in terms of physical and psychological demand, upper-limb neck musculoskeletal disorders (ULNMD) female staff direct contact with elderly nursing homes. A cross-sectional survey was conducted 105 homes France. Data on nursing-home conditions were collected by questionnaire from occupational physicians self-administered staff. Psychosocial demand at work assessed Siegrist's ULNMD Nordic questionnaire. 2,328 employees included:...
This study aimed to evaluate the association between intention leave work, and working conditions health status among female care-staff in nursing homes. A multicenter cross-sectional included 105 homes for elderly. We used validated questionnaires assess occupational, psychosocial medical data a transverse study. Univariate analysis on chi² test was performed with stratification according job (nurse, assistant), variables found be significant each dimension were multivariate models. 1428...
Abstract Breast and ovarian cancers increased in the last decades. Except rare cases with a genetic predisposition high penetrance, these pathologies are viewed as polygenic disease. In this concept, association studies look for variations such polymorphisms low penetrance genes, i.e . genes interaction environmental factors. DNA repair systems that protect genome from deleterious endogenous exogenous damages have been shown to significantly reduced. particular, enzymes of nucleotide...
Although the rate of breast cancer differs between women in Asian and Western countries, molecular genetics/genomics basis this epidemiological observation remains elusive. Moreover, intake phytoestrogens is associated with a lower incidence cancer. Genistein daidzein are primary soy isoflavones chemical structure similar to estrogens. Conceivably, actions on gene expression signatures might mediate their postulated effects pathogenesis. The present study evaluated transcriptional...
The biomonitoring of nanoparticles in patients’ broncho-alveolar lavages (BAL) could allow getting insights into the role inhaled biopersistent etiology/development some respiratory diseases. Our objective was to investigate relationship between BAL, interstitial lung diseases and occupational exposure these particles released unintentionally. We analyzed data from a cohort 100 patients suffering (NanoPI clinical trial, ClinicalTrials.gov Identifier: NCT02549248) observed that most showed...
Aim To evaluate knowledge and perception of hepatitis B, including prevention, among Moroccan health care workers (HCWs) to estimate seroprevalence B vaccine coverage (VC). Methods Four hundred twenty HCWs were randomly selected stratified by site: 120 in Rabat, 140 Taza 160 Témara–Skhirat. The study included an anonymous questionnaire about its prevention a serological survey. Oral statements registers used analyse the VC HCWs. Serological testing analysed according occupational exposure....
The COVID-19 pandemic led to a change in work organization with the development of telework. purpose this study was assess prevalence anxiety and depressive symptoms teleworking staff university hospital center France during first lockdown, identify personal, medical occupational factors associated disorder.A cross-sectional observational conducted 474 working from home lockdown. sociodemographic, information (anxiety disorders measured on Hospital Anxiety Depression (HAD) scale) collected...
The purpose of this study was to assess the prevalence psychological distress in medical students during COVID-19 health crisis and identify factors associated with distress. A cross-sectional observational presented 1814 (from first sixth year) a French university hospital center. Sociodemographic, occupational information (psychological measured on GHQ12 scale) were collected via an online anonymous self-administered questionnaire. Variables investigated using univariate analysis...
Introduction: The COVID-19 pandemic implied a period of lockdown for the general population, increasing risk to develop some physical or mental disorders. In fibromyalgia patients, these disorders are part large clinical picture syndrome. Fibromyalgia management is especially based on regular practice activity. Lockdown imposed break in rhythms, requiring restructuring scheduling. Thus, present study aimed investigate experiences patients during using qualitative analysis. Method: 19 (52 ± 9...
Objectives The present study sought to quantify the impaired mental well-being and psychosocial stress experienced by nursing home staff determine relationship between assessed on 12-item General Health Questionnaire (GHQ-12) exposure Siegrist's effort/reward overcommitment model. Methods A transverse was conducted in France 2471 female employees 105 homes for elderly. Personal occupational data were collected questionnaire 668 housekeepers, 1454 assistants 349 nurses. Results 36.8% of...
Abstract Background Influenza is an important cause of viral hospital-acquired infection involving patients, healthcare workers (HCW), and visitors. The frequency asymptomatic influenza among HCW with possible subsequent transmission poorly described. objective to determine the cumulative incidence asymptomatic, paucisymptomatic, symptomatic HCW. Method A multicenter prospective cohort study was done in 5 French university hospitals, including 289 during 2016–2017 season. had 3 physical...
Background: Nursing homes were particularly affected by the COVID-19 pandemic. The purpose of this study was to evaluate qualitatively and quantitatively with use a self-reported questionnaire as tool for screening mental disorders in nursing home staff. Methods: A multicenter epidemiological conducted 12 France 1117 staff eligible. Socio-demographic, occupational, medical data collected anonymous using validated scales assess anxiety/depressive symptoms (HAD scale) post-traumatic stress...