A5001504891- Antibiotic Resistance in Bacteria
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial biofilms and quorum sensing
- Reproductive Biology and Fertility
- Bat Biology and Ecology Studies
- Bacterial Identification and Susceptibility Testing
- Network Packet Processing and Optimization
- Algorithms and Data Compression
- Plant Pathogenic Bacteria Studies
- Species Distribution and Climate Change
- Cardiac Ischemia and Reperfusion
- Genomics and Chromatin Dynamics
- RNA Interference and Gene Delivery
- Antibiotic Use and Resistance
- Smart Grid Security and Resilience
- Transgenic Plants and Applications
- Analytical Chemistry and Sensors
- Plant-Microbe Interactions and Immunity
- Leptospirosis research and findings
- Pluripotent Stem Cells Research
- Electrochemical Analysis and Applications
- Infections and bacterial resistance
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
National Taiwan University of Science and Technology
2024
Biodiversity Research Center, Academia Sinica
2019-2024
National Cheng Kung University
2016-2018
National Taiwan Normal University
2018
National Taiwan University
2009-2017
Chang Gung University
2017
National Tsing Hua University
2012-2016
Czech Academy of Sciences, Institute of Biotechnology
2015
National Taiwan University Hospital
2011
This study investigated the correlation between antibiotic consumption and antimicrobial resistance in Gram-negative bacteria causing healthcare-associated infections at a university hospital Taiwan from 2000 to 2009.Disc susceptibility data of Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens, Proteus spp., Pseudomonas aeruginosa, Acinetobacter Stenotrophomonas maltophilia other non-fermentative bacilli were evaluated. Data on annual patient-days (defined...
Abstract Studies on the halotolerance of bacteria are attractive to fermentation industry. However, a lack sufficient genomic information has precluded an investigation Halomonas beimenensis . Here, we describe molecular mechanisms saline adaptation in H. based high-throughput omics and Tn5 transposon mutagenesis. The genome is 4.05 Mbp contains 3,807 genes, which were sequenced using short long reads obtained via deep sequencing. Sixteen mutants with loss identified. Orthologs mutated such...
Abstract Rhodopseudomonas palustris strains PS3 and YSC3 are purple non-sulfur phototrophic bacteria isolated from Taiwanese paddy soils. has beneficial effects on plant growth enhances the uptake efficiency of applied fertilizer nutrients. In contrast, no significant effect growth. The genomic structures similar; each contains one circular chromosome that is 5,269,926 or 5,371,816 bp in size, with 4,799 4,907 protein-coding genes, respectively. this study, a large class genes involved...
Carbapenem-resistance in Acinetobacter baumannii has gradually become a global challenge. To identify the genes involved carbapenem resistance A. baumannii, transcriptomic responses of completely sequenced strain ATCC 17978 selected with 0.5 mg/L (IPM-2 m) and 2 (IPM-8 imipenem were investigated using RNA-sequencing to differences gene expression patterns. A total 88 68 differentially expressed response IPM-2 m IPM-8 selection, respectively. Among genes, 50 highly m, 30 38 common both...
Trimming low quality bases from sequencing reads is considered as routine procedure for genome assembly; however, we know little about its pros and cons. Here, used empirical data to examine how read trimming affects assembled computational time a widespread East Asian passerine, the rufous-capped babbler (Cyanoderma ruficeps Blyth). We found that scaffolds raw were always longer than those trimmed ones, whereas times former sometimes much latter. Nevertheless, assembly completeness showed...
Specialization in narrow ecological niches may not only help species to survive competitive or unique environments but also contribute their extermination over evolutionary time. Although the "evolutionary dead end" hypothesis has long been debated, empirical evidence from with detailed information on niche specialization and history remains rare. Here we use a group of four closely related Cnemaspis gecko that depend highly granite boulder caves Mekong Delta investigate potential impact...
Acinetobacter baumannii has emerged recently as a major cause of health care-associated infections due to the extent its antimicrobial resistance and propensity large nosocomial outbreaks. Here we report genome sequence TYTH-1 isolated in Taiwan during 2008.
Nuclear transfer (NT) is a technique used to investigate the development and reprogramming potential of single cell. DNA methyltransferase-3-like, which has been characterized as repressive transcriptional regulator, expressed in naturally fertilized egg morula/blastocyst at pre-implantation stages. In this study, we demonstrate that use Dnmt3l-knockout (Dnmt3l-KO) donor cells combination with Trichostatin A treatment improved developmental efficiency quality cloned embryos. Compared WT...
This study aims to investigate the effects of nitrogen flow rate (0–2.5 sccm) on structure and properties TiZrN films. Nanocrystalline thin films were deposited Si (001) substrates by unbalanced magnetron sputtering. The major phase, texture, N/(Ti + Zr) ratio, thickness, hardness, residual stress, resistivity content played an important role in phase transition. With increasing rate, changed from mixed TiZr phases a single phase. X-ray diffraction results indicated that (111) was preferred...
Domesticated species are valuable models to examine phenotypic evolution, and knowledge on domestication history is critical for understanding the trajectories of evolutionary changes. Sequentially Markov Coalescent often used infer history. However, practices may obscure signal left by population history, affecting demographic inference. Here we assembled genomes a recently domesticated species-the society finch-and its parent white-rumped munia-to We applied genomic analyses two finch...
Abstract Many transcribed RNAs are non-coding RNAs, including microRNAs (miRNAs), which bind to complementary sequences on messenger regulate the translation efficacy. Therefore, identifying miRNAs expressed in cells/organisms aids understanding genetic control cells/organisms. In this report, we determined binding of oligonucleotides a receptor-modified silicon nanowire field-effect transistor (SiNW-FET) by monitoring changes conductance SiNW-FET. We first modified SiNW-FET with DNA probe...
Organisms often acquire physiological and morphological modifications to conquer ecological challenges when colonizing new environments which lead their adaptive evolution. However, deciphering the genomic mechanism of adaptation is difficult because are too complex for straightforward interpretation. Thus, we examined a widespread songbird-the rufous-capped babbler (Cyanoderma ruficeps)-to relatively simple system: distinct across elevational gradients on mountainous island Taiwan. We...
This study employed genomewide analysis to investigate potential resistance mechanisms in Acinetobacter baumannii following imipenem exposure. Imipenem-selected mutants were generated from the imipenem-susceptible strain ATCC 17978 by multistep selection resistance. Antibiotic susceptibilities examined, and selected originated confirmed pulsed-field gel electrophoresis. The genomic sequence of a resistant mutant was analyzed using next-generation sequencing platform, genetic recombination...
The presence of feathers is a vital characteristic among birds, yet most modern birds had no feather on their feet. discoveries the hind limbs basal and dinosaurs have sparked an interest in evolutionary origin genetic mechanism feathered However, majority studies investigating genes associated with this trait focused domestic populations. Understanding underpinned feathered-foot development wild still its infancy. Here, we assembled chromosome-level genome Asian house martin (Delichon...
Nest building is a vital behavior exhibited during breeding in birds, and possibly induced by environmental social cues. Although such behavioral plasticity has been hypothesized to be controlled adult neuronal plasticity, empirical evidence, especially at the neurogenomic level, remains limited. Here, we aim uncover gene regulatory networks that govern avian nest construction examine whether they are associated with circuit rewiring. We designed an experiment dissect this complex into...