A5100330625- MicroRNA in disease regulation
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Cancer-related molecular mechanisms research
- Vitamin D Research Studies
- Galectins and Cancer Biology
- Circular RNAs in diseases
- Peptidase Inhibition and Analysis
- Infectious Diseases and Tuberculosis
- Cancer Research and Treatments
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Bone and Dental Protein Studies
- Pregnancy and preeclampsia studies
- Virus-based gene therapy research
- Moyamoya disease diagnosis and treatment
- NF-κB Signaling Pathways
- Liver Diseases and Immunity
- dental development and anomalies
- Cytokine Signaling Pathways and Interactions
- Connective tissue disorders research
- Retinal and Macular Surgery
- Retinopathy of Prematurity Studies
- Intraocular Surgery and Lenses
- Nanoparticle-Based Drug Delivery
Sichuan University
2010-2023
West China Hospital of Sichuan University
2010-2023
Chongqing Medical University
2021
Second Affiliated Hospital of Chongqing Medical University
2021
Dalian Medical University
2021
Affiliated Hospital of Zunyi Medical College
2017
The aim of the present study was to investigate role microRNA (miRNA or miR)-140 in C3H10T1/2 mesenchymal stem cells (MSCs). Cluster analysis used evaluate miRNA expression profile. level miRNA‑140 validated by reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR). TargetScan and microRNA.org databases were predict target miRNAs cartilage‑associated genes. Binding sites between miR‑140 gene predicted bioinformatics software. A dual‑luciferase reporter assay performed...
The present study aimed to investigate the mechanisms underlying microRNA (miRNA)‑mediated regulation of chondrogenic differentiation. Mouse embryo‑derived stem cells C3H10T1/2 were cultured and differentiation was induced using transforming growth factor‑β3 (TGF‑β3). In addition, miRNA expression profiles detected via array analysis, quantitative polymerase chain reaction performed verify differentially expressed miRNAs. Furthermore, bioinformatics software used predict putative targets...
Abstract Besides its well‐known benefits on human health, calcitriol, the hormonally active form of vitamin D 3 , has been being evaluated in clinical trials as an anticancer agent. However, currently available results are contradictory and not fundamentally deciphered. To best our knowledge, hypercalcemia caused by high‐dose calcitriol administration low bioavailability limit investigations translations. Here, we show that one‐step self‐assembly amphiphilic cholesterol‐based conjugates...
Abstract By investigating the expression profiles of miR‐19a and metalloproteinases ( MMP13) in human fibroblast‐like synoviocytes‐rheumatoid arthritis (HFLS‐RA) HFL cells lines, this study intends to confirm directly target connection between them reveal effect suppressing MMP13 on HLFS‐RA migration, invasion apoptosis. After screening abnormal expressed messenger RNAs microRNAs synovial tissues patients with RA, underlying pathway was determined by Kyoto Encyclopedia Genes Genomes (KEGG)...
In the article by Davidson et al in July 2013 issue of Arthritis & Rheumatism (pages 1747–1752), name sixth author was omitted. The is Marina Donskoi, BS (University Queensland Diamantina Institute and Princess Alexandra Hospital, Brisbane, Queensland, Australia). We regret errors.
Objective To observe the safety and efficacy of posterior vitreous detachment (PVD) induced by combined intravetreal injection lysine-plasminogen reteplase in rabbits. Methods Fifteen healthy New Zealand rabbits were divided into three groups with five each. Take right eyes as experimental eyes, while left control. The received 1250 μg/ml at 0. 1 ml dose 104U,3×104 U, 105U 0.05 recpectively, control injected intravetreally 15 balanced salt solution. conjunctiva, anterior chamber, lens, body,...