A5062741293- Genetics, Bioinformatics, and Biomedical Research
- Genomics and Phylogenetic Studies
- Biomedical and Engineering Education
- Research Data Management Practices
- Scientific Computing and Data Management
- Neurobiology and Insect Physiology Research
- Neuroscience and Neural Engineering
- Ion channel regulation and function
- vaccines and immunoinformatics approaches
- Educational Tools and Methods
- Lipid Membrane Structure and Behavior
- Neuropeptides and Animal Physiology
- Environmental Toxicology and Ecotoxicology
- Phytase and its Applications
- Deception detection and forensic psychology
- Palliative Care and End-of-Life Issues
- Advanced Proteomics Techniques and Applications
- Open Education and E-Learning
- Electronic Health Records Systems
- Insect Resistance and Genetics
- Ubiquitin and proteasome pathways
- Gene expression and cancer classification
- Robotics and Automated Systems
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Invertebrate Immune Response Mechanisms
Instituto Gulbenkian de Ciência
2009-2020
University of Lisbon
2017-2018
European Bioinformatics Institute
2011-2014
Sainsbury Laboratory
2014
Norwich Research Park
2014
Netherlands Bioinformatics Centre
2013-2014
Centro de Investigación del Cáncer
2011-2013
SIB Swiss Institute of Bioinformatics
2008-2013
European Molecular Biology Laboratory
2013
Sapienza University of Rome
2013
Africa is not unique in its need for basic bioinformatics training individuals from a diverse range of academic backgrounds. However, particular logistical challenges Africa, most notably access to expertise and internet stability, must be addressed order meet this on the continent. H3ABioNet (www.h3abionet.org), Pan African Bioinformatics Network H3Africa, has therefore developed an innovative, free-of-charge "Introduction Bioinformatics" course, taking these into account as part...
The mountains of data thrusting from the new landscape modern high-throughput biology are irrevocably changing biomedical research and creating a near-insatiable demand for training in management manipulation mining analysis. Among life scientists, clinicians to environmental researchers, common theme is need not just use, gain familiarity with, bioinformatics tools resources but also understand their underlying fundamental theoretical practical concepts. Providing empower scientists handle...
1. A method of estimating absolute ionic permeability coefficients which does not depend on the use impermeant substitutes is reported. 2. The based a pump leak model Xenopus laevis oocyte membrane. procedure consists measuring, in same experiment, current and currents generated under voltage clamp by partial substitution one or two ions at time. For each experimental condition, measured are substituted Goldman-Hodgkin-Katz type equation with unknowns (the coefficients). set equations thus...
Abstract Summary: Rapid technological advances have led to an explosion of biomedical data in recent years. The pace change has inspired new collaborative approaches for sharing materials and resources help train life scientists both the use cutting-edge bioinformatics tools databases how analyse interpret large datasets. A prototype platform such training was recently created by Bioinformatics Training Network (BTN). Building on this work, we a centralized portal courses, including...
ABSTRACT When gassed with a CO2-containing mixture, under short-circuit conditions, the isolated outer mantle epithelium (OME) of Anodonta cygnea generated current which exhibited cyclic variations throughout year. The intracellular potential, had an average value –31 ±0·5 mV (N =65). potential was sensitive to changes in concentration potassium and chloride on haemolymph side preparation, but not shell side, insensitive sodium either side. preparation pure oxygen fell by 85 ± 1% = 8). A...
Summary The synthesis of di‐ myo ‐inositol phosphate (DIP), a common compatible solute in hyperthermophiles, involves the consecutive actions inositol‐1‐phosphate cytidylyltransferase (IPCT) and synthase (DIPPS). In most cases, both activities are present single gene product, but separate genes also found few organisms. Genes for IPCT DIPPS were genomes 33 organisms, all with thermophilic/hyperthermophilic lifestyles. Phylogeny IPCT/DIPPS revealed an incongruent topology 16S RNA phylogeny,...
The 2011 AGM workshop took place at the Instituto Gulbenkian de Ciência (IGC) in Oeiras, Portugal, from 23-25 May. goal of was to build on demonstrable progress made during previous year, particular by helping deliver some plans outlined 2010 AGM. It also an opportunity our commitment take EMBnet forward embracing new partners and activities. following pages summarise content, discussions conclusions.
Programmatic access to data and tools through the web using so-called services has an important role play in bioinformatics. In this article, we discuss most popular approaches based on SOAP/WS-I REST describe our, a cross section of community, experiences with providing context biological sequence analysis. We briefly review main technological as well best practice hints that are useful for both users developers. Finally, syntactic semantic integration issues multiple discussed.
Demand for training life scientists in bioinformatics methods, tools and resources computational approaches is urgent growing. To meet this demand, new trainers must be prepared with effective teaching practices delivering short hands-on sessions-a specific type of education that not typically part professional preparation many countries. A Train-the-Trainer (TtT) programme was created by adapting existing models, using input from experienced experts bioinformatics, educational cognitive...
The transport of Na+, K+ and Cl- across the isolated epithelium eel intestine was studied using a combination four experimental strategies: short-circuiting, measurements intracellular potentials ion concentrations, application variety inhibitors measurement unidirectional fluxes with radioactive tracers. When short-circuited, system performs net Na+ towards blood side, stoichiometry approaching 2, much smaller lumen. is totally driven by sodium pump located in basolateral barrier main...
<ns3:p>One of the main goals ELIXIR-EXCELERATE project from European Union’s Horizon 2020 programme is to support a pan-European training increase bioinformatics capacity and competency across ELIXIR Nodes. To this end, Train-the-Trainer (TtT) has been developed by TtT subtask EXCELERATE’s Training Platform, try expose instructors aspects pedagogy evidence-based learning principles, help them better design, develop deliver high-quality in future. As first step towards such programme, an...
ELIXIR is a pan-European intergovernmental organisation for life science that aims to coordinate bioinformatics resources in single infrastructure across Europe; training central its strategy, which develop community spans all member states. In an evidence-based approach strengthening programmes Europe, the Training Platform, led by EXCELERATE Quality and Impact Assessment Subtask collaboration with Coordinators Group, has implemented assessment strategy measure quality impact of entire...
ABSTRACT Under short-circuit conditions the outer mantle epithelium of Anodonta cygnea is known to produce an acidification solution bathing shell side and alkalinization haemolymph side. At steady state, rates secretion acid base were numerically equal simultaneously measured current, expressed in same units. The secretion, showed close similarity reductions caused by anoxia, diamox, DIDS (from side), DNP iodoacetamide. current (Isc) was sensitive concentration CO2, bicarbonate or protons...
1. Membrane potential and conductances short‐circuit current were continuously measured with microelectrodes conventional electrophysiological techniques in a stripped preparation of frog skin epithelium. The effects the removal chloride or sodium ions concentration dilution serosal (inner) bathing solution studied. 2. Chloride‐ sodium‐free solutions produced cell depolarization about 30 mV parallel fall current. Mucosal membrane both decreased permeability mucosal barrier was calculated to...
O câncer de mama é uma doença que afeta principalmente as mulheres e segundo estatísticas esta vem aumentando com certa frequência nos países ocidentais, isto tem preocupado a comunidade científica. Esta está associada diversos fatores risco, sendo dieta um fator demonstrado relação promoção mama. Uma alimentação rica em substância funcional sido alvo atenção, pois os fitoestrógenos têm mostrado através estudos experimentais, propriedades benéficas à saúde, parece contribuir para redução do...
The Gulbenkian Training Programme in Bioinformatics has been offering hands-on training courses Oeiras, PT for more than a decade. This article is review of its functional organization and evolution. We aim to share our experience with people considering setting-up similar facilities elsewhere. More 1600 course attendees, so far, have attended courses. Their experiences helped us know how satisfy their requirements what feasible very limited resources.
In the last decade, bioinformatics has become an indispensable branch of modern science research, experiencing explosion in financial support, developed applications and data collection. The growth datasets that are emerging from research laboratories, industry, health sector, etc., increasingly raising levels demand computing power storage. Processing biological data, large scales these datasets, often requires use High Performance Computing (HPC) resources, especially when dealing with...
Abstract Summary: We present iAnn, an open source community-driven platform for dissemination of life science events, such as courses, conferences and workshops. iAnn allows automatic visualisation integration customised event reports. A central repository lies at the core platform: curators add submitted these are subsequently accessed via web services. Thus, once widget is incorporated into a website, it permanently shows timely relevant information if were native to remote site. At same...
EMBER was a European project aiming to develop bioinformatics teaching materials on the Web and CD-ROM help address recognised skills shortage in bioinformatics. The grew out of pilot work development an interactive web-based tutorial desire repackage that resource with professional multimedia publisher. We report here completion its current status: website is now accessible from http://www.ember.man.ac.uk