A5082242349- Genetics, Bioinformatics, and Biomedical Research
- Research Data Management Practices
- Scientific Computing and Data Management
- Advanced Proteomics Techniques and Applications
- Genomics and Phylogenetic Studies
- Bioinformatics and Genomic Networks
- Metabolomics and Mass Spectrometry Studies
- Biomedical Text Mining and Ontologies
- Biomedical and Engineering Education
- Cancer Genomics and Diagnostics
- Cell Image Analysis Techniques
- HIV Research and Treatment
- Explainable Artificial Intelligence (XAI)
- Plant Pathogens and Fungal Diseases
- Urinary Tract Infections Management
- Data Quality and Management
- Plant-Microbe Interactions and Immunity
- Chromosomal and Genetic Variations
- Monoclonal and Polyclonal Antibodies Research
- Cardiac tumors and thrombi
- Essential Oils and Antimicrobial Activity
- Health Sciences Research and Education
- Cancer Immunotherapy and Biomarkers
- Genomic variations and chromosomal abnormalities
- Mycorrhizal Fungi and Plant Interactions
Genopole (France)
2022-2024
OLS
2022
Institut Français de Bioinformatique
2018-2021
Université Paris-Saclay
2018-2021
Centre National de la Recherche Scientifique
2002-2021
Genoscope
2020
Hospital Arnau de Vilanova
2018
Genome Research Foundation
2011
National University of Quilmes
2011
Centre Hospitalier de Versailles
2009
Fungi are of primary ecological, biotechnological and economic importance. Many fundamental biological processes that shared by animals fungi studied in due to their experimental tractability. pathogens or mutualists model systems analyse effector genes mechanisms diversification. In this study, we report the genome sequence phytopathogenic ascomycete Leptosphaeria maculans characterize its repertoire protein effectors. The L. has an unusual bipartite structure with alternating distinct...
The FAIR Guiding Principles, published in 2016, aim to improve the findability, accessibility, interoperability and reusability of digital research objects for both humans machines.Until now principles have been mostly applied data.The ideas behind these are, however, also directly relevant software.Hence there is a distinct need explore how can be software.In this work, we summarize current status debate around software, as basis development community-agreed software future.We discuss what...
As a part of the ELIXIR-EXCELERATE efforts in capacity building, we present here 10 steps to facilitate researchers getting started genome assembly and annotation. The guidelines given are broadly applicable, intended be stable over time, cover all aspects from start finish general annotation project. Intrinsic properties genomes discussed, as is importance using high quality DNA. Different sequencing technologies generally applicable workflows for also detailed. We structural functional...
<ns4:p>Software Containers are changing the way scientists and researchers develop, deploy exchange scientific software. They allow labs of all sizes to easily install bioinformatics software, maintain multiple versions same software combine tools into powerful analysis pipelines. However, containers packages should be produced under certain rules standards in order reusable, compatible easy integrate pipelines workflows. Here, we presented a set recommendations developed by BioContainers...
Biology is generating more data than ever. As a result, there an ever increasing number of publicly available databases that analyse, integrate and summarize the data, providing invaluable resource for biological community. this trend continues, pressing need to organize, catalogue rate these resources, so information they contain can be most effectively exploited. MetaBase (MB) (http://MetaDatabase.Org) community-curated database containing 2000 commonly used databases. Each entry...
Software Containers are changing the way scientists and researchers develop, deploy exchange scientific software. They allow labs of all sizes to easily install bioinformatics software, maintain multiple versions same software combine tools into powerful analysis pipelines. However, containers packages should be produced under certain rules standards in order reusable, compatible easy integrate pipelines workflows. Here, we presented a set recommendations developed by BioContainers Community...
Protein phosphatase types 1 (PP1) and 2A (PP2A) represent two major families of serine/threonine protein phosphatases that have been implicated in the regulation many cellular processes, including cell growth apoptosis mammalian cells. PP1 PP2A proteins are composed oligomeric complexes comprising a catalytic structure (PP1c or PP2AC) containing enzymatic activity at least one more interacting subunit. The binding different subunits to generates broad variety holoenzymes. We showed here...
Metabolomics, the youngest of major omics technologies, is supported by an active community researchers and infrastructure developers across Europe. To coordinate focus efforts around building for metabolomics within Europe, a workshop on "Future in ELIXIR" was organised at Frankfurt Airport Germany. This one-day strategic involved representatives ELIXIR Nodes, members PhenoMeNal consortium developing e-infrastructure that supports workflow-based analysis pipelines, experts from...
Abstract The secreted proteins (secretome) of fungi play a key role in interactions pathogenic and symbiotic with plants. Using the plant fungus Leptosphaeria maculans symbiont Laccaria bicolor grown culture, we have established proteomic protocol for extraction, concentration resolution fungal secretome. As no data were available on mycelium tissues from both L . , mycelial studied; they also helped verifying purity secretome samples. quality protein extracts was initially assessed by 1‐DE...
<ns4:p>In this white paper, we describe the founding of a new ELIXIR Community - Systems Biology and its proposed future contributions to both broader community systems biologists in Europe worldwide. The believes that infrastructure aspects biology databases, (modelling) tools standards development, as well training access cloud are not only appropriate components infrastructure, but will prove key ELIXIR’s support advanced biological applications personalised medicine. By way series...
ELIXIR is a pan-European intergovernmental organisation for life science that aims to coordinate bioinformatics resources in single infrastructure across Europe; training central its strategy, which develop community spans all member states. In an evidence-based approach strengthening programmes Europe, the Training Platform, led by EXCELERATE Quality and Impact Assessment Subtask collaboration with Coordinators Group, has implemented assessment strategy measure quality impact of entire...
OPINION article Front. Educ., 27 July 2021Sec.STEM Education https://doi.org/10.3389/feduc.2021.710971
<ns4:p>Metabolomics, the youngest of major omics technologies, is supported by an active community researchers and infrastructure developers across Europe. To coordinate focus efforts around building for metabolomics within Europe, a workshop on “Future in ELIXIR” was organised at Frankfurt Airport Germany. This one-day strategic involved representatives ELIXIR Nodes, members PhenoMeNal consortium developing e-infrastructure that supports workflow-based analysis pipelines, experts from...
Human cytomegalovirus (HCMV)-specific antibody responses in HIV-1 infected individuals either with or without HCMV end-organ disease were examined to determine the whether development of was associated a particular deficit response. Anti-whole HCMV, anti-glycoprotein B (gB), and neutralizing levels higher than healthy immunocompetent subjects, particularly patients AIDS HCMV-associated disease. Irrespective location spread disease, who had received anti-HCMV therapy prior sampling exhibited...
In this white paper, we describe the founding of a new ELIXIR Community - Systems Biology and its proposed future contributions to both broader community systems biologists in Europe worldwide. The believes that infrastructure aspects biology databases, (modelling) tools standards development, as well training access cloud are not only appropriate components infrastructure, but will prove key ELIXIR's support advanced biological applications personalised medicine. By way series meetings,...
<ns4:p>Copy number variations (CNVs) are major causative contributors both in the genesis of genetic diseases and human neoplasias. While “High-Throughput” sequencing technologies increasingly becoming primary choice for genomic screening analysis, their ability to efficiently detect CNVs is still heterogeneous remains be developed. The aim this white paper provide a guiding framework future contributions ELIXIR’s recently established <ns4:italic>h</ns4:italic><ns4:italic>uman CNV Community,...