A5005624489- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Plant Virus Research Studies
- Gut microbiota and health
- Plant Pathogens and Resistance
- Aquaculture disease management and microbiota
- Microbial Community Ecology and Physiology
- Biofuel production and bioconversion
- Viral gastroenteritis research and epidemiology
- Microbial Metabolic Engineering and Bioproduction
- Plant and Fungal Interactions Research
- Respiratory viral infections research
- Enzyme Production and Characterization
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Enzyme Catalysis and Immobilization
- RNA and protein synthesis mechanisms
- Genetics, Bioinformatics, and Biomedical Research
- Sperm and Testicular Function
- Diet and metabolism studies
- Microbial Metabolites in Food Biotechnology
- Clostridium difficile and Clostridium perfringens research
- Invertebrate Immune Response Mechanisms
- Animal Virus Infections Studies
- Coffee research and impacts
Universidad de Los Andes
2016-2025
Universidad de Los Andes
2016-2025
The University of Texas at Austin
2023-2024
Washington University in St. Louis
2015-2024
Hospital Universitario Virgen del Rocío
2022-2024
Universidad Rey Juan Carlos
2022
Universidad Francisco de Vitoria
2022
Camilo José Cela University
2022
Universidad de Granada
2000-2022
Center for Rheumatology
2022
Soil microbiota represent one of the ancient evolutionary origins antibiotic resistance and have been proposed as a reservoir genes available for exchange with clinical pathogens. Using high-throughput functional metagenomic approach in conjunction pipeline de novo assembly short-read sequence data from selections (termed PARFuMS), we provide evidence recent between environmental bacteria We describe multidrug-resistant soil containing cassettes against five classes antibiotics (β-lactams,...
The proportion of the human gut bacterial community that is recalcitrant to culture remains poorly defined. In this report, we combine high-throughput anaerobic culturing techniques with gnotobiotic animal husbandry and metagenomics show fecal microbiota consists largely taxa predicted functions are represented in its readily cultured members. When transplanted into mice, complete communities exhibit similar colonization dynamics, biogeographical distribution, responses dietary...
This paper presents standards and best practices for reporting genome sequences of uncultivated viruses. We present an extension the Minimum Information about any (x) Sequence (MIxS) standard virus genomes. Uncultivated Virus Genome (MIUViG) were developed within Genomic Standards Consortium framework include origin, quality, annotation, taxonomic classification, biogeographic distribution in silico host prediction. Community-wide adoption MIUViG standards, which complement a Single...
Significance A consortium of sequenced human gut bacteria was introduced into germ-free mice followed by a “staged” phage attack with virus-like particles purified from the fecal microbiota five healthy adult humans. Unique phages were identified attacking members in nonsimultaneous fashion. Some host bacterial species acquired resistance to through ecological or epigenetic mechanisms. Changes community structure observed after transient. Spontaneous induction prophages present seven taxa...
Significance Childhood malnutrition is a global health problem not attributable to food insecurity alone. Sequencing DNA viruses present in fecal microbiota serially sampled from 0- 3-y-old Malawian twin pairs, we identify age-discriminatory that define “program” of assembly phage and eukaryotic components the gut “virome” within across pairs where both cotwins manifest healthy growth. This program perturbed (delayed) members discordant one cotwin develops severe acute other appears by...
Computational thinking (CT) uses concepts that are essential to computing and information science solve problems, design evaluate complex systems, understand human reasoning behavior. This way of has important implications in computer sciences as well almost every other field. Therefore, we contend CT should be taught elementary schools included university’s educational curriculum. Several studies measure the impact teaching programming, analytical thinking, have been conducted. In this...
Abstract This article summarises the activities of Bacterial Viruses Subcommittee International Committee on Taxonomy for period March 2021−March 2022. We provide an overview new taxa proposed in 2021, approved by Executive Committee, and ratified vote Significant changes to taxonomy bacterial viruses were introduced: paraphyletic morphological families Podoviridae , Siphoviridae Myoviridae as well order Caudovirales abolished, a binomial system nomenclature species was established. In...
A universal taxonomy of viruses is essential for a comprehensive view the virus world and communicating complicated evolutionary relationships among viruses. However, there are major differences in conceptualisation approaches to classification nomenclature virologists, clinicians, agronomists, other interested parties. Here, we provide recommendations guide construction coherent taxonomy, based on expert scientific consensus. Firstly, assignments should be congruent with best attainable...
Abstract This article reports changes to virus taxonomy and taxon nomenclature that were approved ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2024. The entire ICTV membership was invited vote 203 taxonomic proposals had been Executive (EC) July 2023 at 55th EC meeting Jena, Germany, or second November 2023. All online vote. Taxonomic additions include one new phylum ( Ambiviricota ), class, nine orders, three suborders, 51 families, 18 subfamilies, 820...
ABSTRACT We have discovered a novel polyomavirus present in multiple human stool samples. The virus was initially identified by shotgun pyrosequencing of DNA purified from virus-like particles isolated sample collected healthy child Malawi. subsequently sequenced the virus' 4,927-bp genome, which has been provisionally named MW (MWPyV). genomic features characteristic family Polyomaviridae but is highly divergent other members this family. It predicted to encode large T antigen and small...
In Brief Study Design. Human and bovine cadaver study in which biochemical measurements magnetic resonance (MR) imaging of intervertebral discs were correlated. Objective. To measure the correlations between T2 relaxation time with water proteoglycan (PG) content discs. Summary Background Data. Measuring times may provide an accurate noninvasive method detecting changes disc biochemistry due to aging or degeneration. Previous studies validate use T1 tissue have used MR relaxometers, lower...
Acute hepatopancreatic necrosis disease (AHPND) has extended rapidly, causing alarming shrimp mortalities. Initially, the only known causative agent was Vibrio parahaemolyticus carrying a plasmid coding for mortal toxins PirVP. Recently, it been found that and hence disease, could be transferred among members of Harveyi clade. The current study performs genomic characterization an isolate capable developing AHPND in shrimp. Mortality studies molecular histopathological analyses showed...
The Andean bear is an endemic species of the tropical Andes who has almost exclusively plant-based diet. Since herbivorous mammals do not carry enzymes for fiber degradation, establishment symbiosis with cellulolytic microorganisms in their gastrointestinal (GI) tract necessary to help them fulfill nutritional needs. Furthermore, as described other mammals, a stable, diverse and balanced gut microbial composition indicator healthy status host; under disturbances this balance can be lost,...
Abstract Background Acute hepatopancreatic necrosis disease (AHPND) is an important shrimp bacterial caused by some Vibrio species. The severity of the impact this on aquaculture worldwide has made it necessary to develop alternatives prophylactic antibiotics use, such as application probiotics. To assess potential use probiotics in order limit detrimental effects AHNPD, we evaluated effect ILI strain, a sp. bacterium and efficient probiotic, using metabarcoding ( 16S rRNA gene)...
Phages and prophages are one of the principal modulators microbial populations. However, much their diversity is still poorly understood. Here, we extracted 33,624 from 13,713 complete prokaryotic genomes to explore prophage relationships with host. Our results reveal that were present in 75% studied. In addition, Enterobacterales significantly enriched prophages. We also found pathogens a significant reservoir Finally, determined relatedness range genomic hosts delimited by evolutionary...
Bacteriophages, viruses specific to bacteria, coexist with their bacterial hosts limited diversity fluctuations in the guts of healthy individuals where they replicate mostly via lysogenic replication. This favors 'piggy-back-the-winner' over 'kill-the-winner' dynamics which are driven by lytic bacteriophage Revisiting deep-viral sequencing data a individual sampled 2.4 years, we explore how these occur. Prophages found assembled metagenomes were also extra-cellularly, as induced phage...
Publication interests should not limit access to public data