A5101974995- Effects of Radiation Exposure
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Oral health in cancer treatment
- Colorectal and Anal Carcinomas
- Lung Cancer Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Gut microbiota and health
- Pediatric Hepatobiliary Diseases and Treatments
- Health and Wellbeing Research
- Gallbladder and Bile Duct Disorders
- Microbial infections and disease research
- Colorectal Cancer Surgical Treatments
- Head and Neck Cancer Studies
- Nutrition, Health and Food Behavior
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Myxozoan Parasites in Aquatic Species
- Renal cell carcinoma treatment
- Esophageal and GI Pathology
- Management of metastatic bone disease
National Cancer Center
2016-2025
Proton (Malaysia)
2024
National University College
2022-2023
New Generation University College
2022-2023
Seoul National University
2006-2023
Seoul National University Hospital
2022-2023
Jeonju University
2017-2018
Beckman Research Institute
2014
Breast Cancer Research Foundation
2014
Brigham and Women's Hospital
2014
To study the elastic properties of medial gastrocnemius (GCM) in children with spastic cerebral palsy.The protocol was approved by Research Ethics Committee hospital, and informed consent obtained from each child's parent. Fifteen palsy (group 1) 13 without neurologic musculoskeletal disabilities 2) were included. Because group 1 included three hemiplegia, total number legs examined 27. Children 2 had both examined, for a 26 studied. The modified Ashworth scale score ankle assessed physical...
Abstract Background In electric field-based cancer treatment, the intensity of field applied to tumor depends on position electrode array, directly affecting efficacy treatment. The present study evaluated effects changing array treatment for pancreatic cancer. Methods A 3D model was created based computed tomography images 13 patients. An placed surface at various positions, and calculated each. Six plans were each patient by rotating ± 15⁰, 30⁰ in axial plane, 10⁰ sagittal plane relative...
Our long-term objective is to create smart room technologies that are aware of the users presence and their behavior can become an active, but not intrusive, part interaction. In this work, we present a multimodal approach for estimating tracking location identity participants including active speaker. design contains three user-monitoring systems: four CCD cameras, omnidirectional camera 16 channel microphone array. The various sensory modalities processed both individually jointly it shown...
Clathrin-dependent endocytosis is an essential cellular process shared by all cell types. Despite this, precisely how regulated in a cell-type-specific manner and this key pathway functions physiologically or pathophysiologically remain largely unknown. PICALM, which encodes the clathrin adaptor protein was originally identified as component of CALM/AF10 leukemia oncogene. Here we show, employing series conditional Picalm knockout mice, that PICALM critically regulates transferrin uptake...
We performed dosimetric comparisons between proton beam therapy and intensity modulated radiotherapy (IMRT) of intracranial germ cell tumors (ICGCTs) arising in various locations the brain.IMRT, passively scattered (PSPT), spot scanning (SSPT) plans were for four different target volumes: whole ventricle (WV), pineal gland (PG), suprasellar (SS), basal ganglia (BG). Five consecutive clinical cases selected from patients treated 2011 2014 each volume. Total 20 17 included analyses with three...
(1) In this study, we developed a deep learning (DL) model that can be used to predict late bladder toxicity. (2) We collected data obtained from 281 uterine cervical cancer patients who underwent definitive radiation therapy. The DL was trained using 16 features, including patient, tumor, treatment, and dose parameters, its performance compared with of multivariable logistic regression the following metrics: accuracy, prediction, recall, F1-score, area under receiver operating...
We performed a prospective phase II study to compare acute toxicity among five different hypofractionated schedules using proton therapy. This was an exploratory analysis investigate the secondary end-point of biochemical failure-free survival (BCFFS) patients with long-term follow-up. Eighty-two T1-3bN0M0 prostate cancer who had not received androgen-deprivation therapy were randomized one arms: Arm 1, 60 cobalt gray equivalent (CGE)/20 fractions/5 weeks; 2, 54 CGE/15 3, 47 CGE/10 4, 35...
Abstract Objective To assess prognostic factors of patients with operable oral cavity squamous cell carcinoma (OSCC), focusing on the associations smoking/alcohol exposure and age. Materials Methods A total 247 OSCC who received curative surgery ± adjuvant radiotherapy were analyzed. The patient subgroups divided according to pretreatment exposure. Individuals aged 45 years or less classified as younger patients. Results median follow‐up was 52.2 months. 5‐year locoregional progression‐free...
To evaluate the efficacy of proton beam therapy (PBT) as an initial treatment in treatment-naïve hepatocellular carcinoma (HCC) patients and to assess prognostic significance albumin-bilirubin (ALBI) grade, 46 HCC treated with PBT were analyzed. The ALBI grade distribution was 1 11 (23.9%) patients, 2 34 (73.9%) 3 (2.2%) patient. median duration follow-up 56.5 months (95% confidence interval [CI], 48.2–64.7). Among disease progression observed 23 (50%) patients: local (6.5%) patients;...
An error resilient three-dimensional (3-D) mesh coding system is proposed in this paper. The encoder uses a shape adaptive data partitioning scheme to alleviate the effect of propagation. input surface coarsely divided into smooth and detailed regions, each region further partitions similar sizes. Then, those are progressively compressed their joint boundaries using boundary edge collapse rule. At decoder, rule facilitates seamless assembly partitions. When no available for partition due...
Abstract Background To compare the short-term tumor response and long-term clinical outcome of two preoperative chemoradiotherapy (CRT) regimens for locally advanced rectal cancer. Methods This study included 231 patients scheduled CRT using chemotherapeutic protocols from April 2003–August 2006. Pelvic radiotherapy (50.4 Gy) was delivered concurrently with capecitabine ( n = 148) or capecitabine/irinotecan 83). Surgery performed 4–8 weeks after completion. Tumor responses to were assessed...
Scrub typhus is the most common febrile disease in Korea during autumn. Jeju Island largest island South and has a distinctive oceanic climate. This study aimed to identify epidemiologic characteristics of scrub on Island.From January 2011 December 2016, 446 patients were diagnosed with Island. The patients' personal data environmental factors that might be related investigated retrospectively analyzed.The median age was 58-years-old (range, 8 91) 43% them worked agricultural, forestry or...
We compared treatment outcomes and toxicities of photon radiotherapy versus proton beam therapy (PBT) evaluated radiation field effects for T1-3 squamous cell carcinoma the thoracic esophagus (EC) without lymph node metastasis. Medical records 77 patients with T1-3N0M0 EC treated between 2011 2019 were retrospectively analyzed. Among these patients, 61 (79.2%) individuals had T1 EC. The initial clinical target volume encompassed whole or supraclavicular and/or abdominal nodes (extended-field...
This study aimed to investigate the current status of postoperative management uterine endometrial cancer (EC) in Korea.A mail survey was administered members Korean Gynecologic Oncology Group and Radiation Group. A total 38 gynecologic surgeons (GYNs) 31 radiation oncologists (RO) 43 institutions responded. The questionnaire consisted general questions for clinical decision case questions. GYN RO responses were compared using chi-square statistics.The 2 expert groups had similar based on...
Purpose To evaluate the clinical outcome of high-dose-rate (HDR) interstitial brachytherapy (IBT) in patients with oral cavity cancer. Materials and Methods Sixteen cancer treated HDR remote-control afterloading using 192Ir between 2001 2013 were analyzed retrospectively. Brachytherapy was administered 11 as primary treatment five salvage for recurrence after initial surgery. In 12 patients, external beam radiotherapy (50-55 Gy/25 fractions) combined IBT 21 Gy/7 fractions. addition, sole...
Objective: The effectiveness of adjuvant treatments for resected gallbladder carcinoma (GBC) has remained unclear due to lack randomized controlled trials; thus, the aim present study was evaluate role treatments, including chemoradiotherapy (CRT) and/or chemotherapy (CTx), in patients with GBC. Methods: A total 733 GBC who received curative-intent surgical resection were identified a multi-institutional database. Of patients, 372 (50.8%) did not receive treatment, whereas 215 (29.3%) and...
Background: No studies evaluating the clinical outcomes of radiotherapy (RT) for hepatocellular carcinoma (HCC) in caudate lobe have been available to date. The purpose this study was evaluate effectiveness and safety RT HCC lobe. Material Methods: Seventy patients with treated from a multi-institutional database were included study. median equivalent dose 2 Gy (EQD2) 80.0 10 (range, 31.3–99.3), freedom local progression (FFLP), progression-free survival (PFS), overall (OS) rates evaluated....