A5043887907- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Cancer-related molecular mechanisms research
- CAR-T cell therapy research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Magnesium Oxide Properties and Applications
- Salmonella and Campylobacter epidemiology
- Circular RNAs in diseases
- Advanced ceramic materials synthesis
- Fuel Cells and Related Materials
- Bacteriophages and microbial interactions
- MicroRNA in disease regulation
- Hormonal and reproductive studies
- Corneal Surgery and Treatments
- Enterobacteriaceae and Cronobacter Research
- Metal-Organic Frameworks: Synthesis and Applications
- Concrete and Cement Materials Research
- Viral Infectious Diseases and Gene Expression in Insects
- Sexual function and dysfunction studies
- Immunotherapy and Immune Responses
- Reproductive Health and Technologies
- Silicon Carbide Semiconductor Technologies
- Algorithms and Data Compression
Second Affiliated Hospital of Zhejiang University
2010-2024
Zhejiang University
2011-2024
Yangzhou University
2010-2024
Guangdong Medical College
2021-2024
Guangzhou Medical University
2024
Second Affiliated Hospital of Guangzhou Medical University
2024
Jinhua Academy of Agricultural Sciences
2024
Peking University
2017-2023
Peking University Third Hospital
2017-2023
Shenzhen University
2023
The function of a new long non-coding RNA linc00673 remains unclear. While identified as an oncogenic player in non-small cell lung cancer (NSCLC), was found to be anti-oncogenic pancreatic ductal adenocarcinoma (PDAC). However whether regulated malignancy and epithelial mesenchymal transition (EMT) has not been characterized. Cell proliferation assessed using CCK-8 EdU assays, migration invasion were scratch assays transwell assays. Epithelial examined western blot, qRT-PCR...
The varicella-zoster virus (VZV) vaccine strain may reactivate to cause herpes zoster. Limited data suggest that the risk of zoster in vaccinated children could be lower than with naturally acquired varicella. We examine incidence trends, and epidemiologic clinical features disease among adolescents by vaccination status.Population-based active surveillance was conducted <20 years old residents Antelope Valley, California, from 2000 through 2006. Structured telephone interviews collected...
B7-H3 is an attractive target for immunotherapy because of its high expression across multiple solid tumors, including prostate cancer, and restricted in normal tissues. Among various types tumor immunotherapy, chimeric antigen receptor T (CAR-T) cell therapy has shown remarkable success hematological tumors. However, the potency CAR-T tumors still limited. Here, we examined cancer tissues cells developed a second-generation CAR that specifically targets CD28 as costimulatory to explore...
The lack of diagnostic markers limits the window effectiveness for rheumatoid arthritis (RA) therapies. Here, we isolated exosomes serum samples from four distinct groups RA patients, according to disease activity and with/without medication. Then, total RNA was extracted whole-transcriptome sequencing. Focusing on lncRNA sequencing, gene ontology (GO) kyoto encyclopedia genes genomes (KEGG) pathway enrichment analyses were performed. We found that number upregulated lncRNAs significantly...
Previous studies suggest that air pollution has a negative effect on semen quality. However, most are cross-sectional and the results controversial. This study investigated associations between pollutants (PM2.5, PM10, SO2, NO2, CO, O3) quality among sperm donation candidates, especially when was artificially controlled in Beijing, China. We analyzed 8945 samples human bank of Peking University Third Hospital (Beijing, China) from October 2015 to May 2018. Air data during entire period (0–90...
Abstract IκBα is a critical protein that inhibits NF-κB nuclear translocation and impairs NF-κB–mediated signaling. The abundance of determines the activation restoration inflammatory response. However, posttranslational regulation remains to be fully understood. In this study, we identified ubiquitin-specific protease 39 (USP39) as negative regulator in response by stabilizing basal IκBα. expression USP39 macrophages was reduced under LPS-induced inflammation. Knockdown or knockout...
Studies have shown that rapid eye movement (REM) sleep behavior disorder (RBD) is a subtype of Parkinson's disease (PD) characterized by severe cognitive impairment and progression. However, reliable biological markers are lacking presently. Neurofilament light chain (NFL) glial fibrillary acidic protein (GFAP) been widely studied as biomarkers cognition impairment. This study aimed to find for the RBD PD investigating possible relationship between serum NFL, GFAP levels, subtype. A total...
Male infertility is considered a common health problem, and non-obstructive azoospermia with unclear pathogenesis one of the most challenging tasks for clinicians. The objective this study was to investigate differential serum metabolic pattern in azoospermic men determine potential biomarkers related spermatogenic dysfunction. Serum samples from patients (n = 22) healthy controls 31) were examined using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)....
We isolated eight tigecycline-resistant
Balancing heritage protection and tourism development is currently the major challenge in traditional Chinese villages, while construction of service facilities has substantial effects on both villages. Based theoretical framework living concept, which includes three aspects (villagers, architectures, culture), this paper proposes an indicator system for evaluating The contains dimensions, eight first-level indicators, 19 second-level indicators. An empirical study five villages Zhejiang...
This study aimed to investigate the prevalence and characterization of tet(X4) in Escherichia coli isolates from a pig farm Shanghai, China, elucidate dissemination mechanism this swine farm. Forty-nine (80.33%) E. strains were isolated 61 samples screened for presence tet(X). Among them, six (12.24%) positive exhibited resistance tigecycline (MIC ≥ 16 mg/L). They further sequenced by Illumina Hiseq. Six tet(X4)-positive belonged ST761 with identical genes, profiles, plasmid replicons,...
A molybdovanadosilicic acid H5SiMo11VO40·8H2O was synthesized and investigated in this work. The structure features hydration degree of were characterized by IR, UV, XRD TG-DTA. Its proton conductivity studied electrochemical impedance spectroscopy (EIS). EIS measurements demonstrated that showed excellent conduction performance with reaching 5.70 × 10-3 S cm-1 at 26 °C 70% relative humidity. So, it is a new solid high conductor. enhances the increase temperature, exhibits Arrhenius...
Abstract Background mcr-1- positive Escherichia coli has emerged as a significant threat to human health, veterinary and food safety in recent years. After the prohibition of colistin feed additive animal husbandry China, noticeable reduction both resistance prevalence mcr-1 was observed E. from animals humans. Objectives To assess gene characterize its genetic context strains derived fecal meat samples food-producing China. Methods A total 1,353 836 were collected between 2019 2020 isolates...